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Intraoperative Frozen Biopsy of Central Lymph Node in the Management of Papillary Thyroid Microcarcinoma

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

The purpose of this study was to evaluate the usefulness and accuracy of intraoperative frozen section examination in the diagnosis of metastatic central lymph nodes in comparison to the final histopathological findings. A retrospective review was performed to evaluate patients with a preoperative diagnosis of papillary thyroid microcarcinoma (PTMC) and a plan to perform thyroid lobectomy at our Hospital from September 2011 to September 2013. Sixteen patients were identified. Intraoperative frozen section examination diagnosed ten patients as negative malignant cells of the central lymph node and the remaining six patients as metastatic central lymph node. The final histopathological results corresponded with intraoperative frozen section examination. Intraoperative frozen section examination had a sensitivity, specificity and accuracy of 100 % for diagnosing metastatic central lymph nodes of PTMC. Intraoperative frozen section examination of central lymph nodes is a useful and accurate adjunct for determining the operation method in PTMC.

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Authors and Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, 160 Ilsimri, Hwasun, Jeonnam, 519-809, South Korea

    Dong Hoon Lee, Tae Mi Yoon, Joon Kyoo Lee & Sang Chul Lim

  2. Department of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun, Jeonnam, South Korea

    Hee Kyung Kim & Ho Cheol Kang

Authors
  1. Dong Hoon Lee
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  2. Tae Mi Yoon
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  3. Hee Kyung Kim
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  4. Joon Kyoo Lee
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  5. Ho Cheol Kang
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  6. Sang Chul Lim
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Correspondence to Joon Kyoo Lee.

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All authors declares that we have no conflict of interest and funding.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Lee, D.H., Yoon, T.M., Kim, H.K. et al. Intraoperative Frozen Biopsy of Central Lymph Node in the Management of Papillary Thyroid Microcarcinoma. Indian J Otolaryngol Head Neck Surg 68, 56–59 (2016). https://doi.org/10.1007/s12070-015-0900-1

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  • DOI: https://doi.org/10.1007/s12070-015-0900-1

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