Skip to main content

Advertisement

Log in

Sialolipoma of Minor Salivary Glands: Presentation of Five Cases and Review of the Literature with an Epidemiological Analyze

  • Original Article
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Sialolipoma is rare benign neoplasm arise from salivary glands (majors and minors) characterized by neoplastic adipose tissue with scattered non-neoplastic salivary gland acinus. To date 60 cases (including 5 cases reported in the present paper) have been reported in scientific literature. This article presents 5 new cases of sialolipoma affecting minor salivary glands (MiSG) and additionally reviews and analyzes the previously published cases to assess possible demographical differences between sialolipoma from minor and from major salivary glands. Case reports: 5 cases (3 females; 2 males; age means 63.8 years), of sialolipoma from MiSG, are reported. 2 of them were located in buccal mucosa, 1 in upper lip mucosa, 1 in floor of the mouth and 1 in retromolar area. All tumors were composed by neoplastic adipocytes cells interlaced with normal salivary gland acinus cover it by a fibrous tissue capsule. Analyzes of literature showed that MiSG sialolipoma is most frequent in females over 60 years old, therefore and in conclusion this article assess different demographical profile of sialolipoma in respect to their topography.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Nagao T, Sugano I, Ishida Y et al (2001) Sialolipoma: a report of seven cases of a new variant of salivary gland lipoma. Histopathology 38:30–36

    Article  CAS  PubMed  Google Scholar 

  2. Bansal B, Ramavat AS, Gupta S et al (2007) Congenital sialolipoma of parotid gland: a report of rare and recently described entity with review of literature. Pediatr Dev Pathol 10:244–246

    Article  PubMed  Google Scholar 

  3. Maiorano E, Capodiferro S, Fanelli B, Calabrese L, Napoli A, Favia G (2008) Hamartomatous angiolipoma of the parotid gland. (Sialoangiolipoma). Head Neck Pathol 2:36–40

    Article  PubMed Central  PubMed  Google Scholar 

  4. Hornigold R, Morgan PR, Pearce A, Gleeson MJ (2005) Congenital sialolipoma of the parotid gland first reported case and review of the literature. Int J Pediatr Otorhinolaryngol 69:429–434

    Article  CAS  PubMed  Google Scholar 

  5. Kadivar M, Shahzadi SZ, Javadi M (2007) Sialolipoma of the parotid gland with diffuse sebaceous differentiation in a female child. Pediatr Dev Pathol 10:138–141

    Article  PubMed  Google Scholar 

  6. Doğan S, Can IH, Unlü I, Süngü N, Gönültaş MA, Samim EE (2009) Sialolipoma of the parotid gland. J Craniofac Surg 20:847–848

    Article  PubMed  Google Scholar 

  7. Fritzsche FR, Bode PK, Stinn B, Huber GF, Noske A (2009) Sialolipoma of the parotid gland. Pathologe 30:478–480

    Article  CAS  PubMed  Google Scholar 

  8. Michaelidis IG, Stefanopoulos PK, Sambaziotis D, Zahos MA, Papadimitriou GA (2006) Sialolipoma of the parotid gland. J Craniomaxillofac Surg 34:43–46

    Article  PubMed  Google Scholar 

  9. Baker SE, Jensen JL, Correll RW (1981) Lipomas of the parotid gland. Oral Surg Oral Med Oral Pathol 52:167–171

    Article  CAS  PubMed  Google Scholar 

  10. Walts AE, Perzik SL (1976) Lipomatous lesions of the parotid area. Arch Otolaryngol 102:230–232

    Article  CAS  PubMed  Google Scholar 

  11. Yum DJ, Kang JH, Kim YJ, Kim SW (2008) Sialolipoma of the parotid gland. Korean J Otolaryngol-Head Neck Surg 51:371–375

    Google Scholar 

  12. Jang YW, Kim SG, Pai H, Park JW, Lee YC, Rotaru H (2009) Sialolipoma: case report and review of 27 cases. Oral Maxillofac Surg 13:109–113

    Article  PubMed  Google Scholar 

  13. Pusiol T, Franceschetti I, Scialpi M, Piscioli I (2009) Oncocytic sialolipoma of the submandibular gland with sebaceous differentiation: a new pathological entity. Indian J Pathol Microbiol 52:379–382

    Article  PubMed  Google Scholar 

  14. Parente P, Longobardi G, Bigotti G (2008) Hamartomatous sialolipoma of the submandibular gland: case report. Br J Oral Maxillofac Surg 46:599–600

    Article  PubMed  Google Scholar 

  15. Fregnani ER, Pires FR, Falzoni R, Lopes MA, Vargas PA (2003) Lipomas of the oral cavity: clinical findings, histological classification and proliferative activity of 46 cases. Int J Oral Maxillofac Surg 32:49–53

    Article  CAS  PubMed  Google Scholar 

  16. Ramer N, Lumerman HS, Ramer Y (2007) Sialolipoma: report of two cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:809–813

    Article  PubMed  Google Scholar 

  17. Ponniah I, Lavanya N, SureshKumar P (2007) Island of salivary gland in adipose tissue: a report of three cases. J Oral Pathol Med 36:558–562

    Article  CAS  PubMed  Google Scholar 

  18. Sakai T, Iida S, Kishino M, Okura M, Kogo M (2006) Sialolipoma of the hard palate. J Oral Pathol Med 35:376–378

    Article  PubMed  Google Scholar 

  19. Okada H, Yokoyama M, Hara M, Akimoto Y, Kaneda T, Yamamoto H (2009) Sialolipoma of the palate: a rare case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:571–576

    Article  PubMed  Google Scholar 

  20. Lin YJ, Lin LM, Chen YK et al (2004) Sialolipoma of the floor of the mouth: a case report. Kaohsiung J Med Sci 20:410–414

    Article  PubMed  Google Scholar 

  21. Agaimy A, Ihrler S, Märkl B et al (2013) Lipomatous salivary gland tumors: a series of 31 cases spanning their morphologic spectrum with emphasis on sialolipoma and oncocytic lipoadenoma. Am J Surg Pathol 37:128–137

    Article  PubMed  Google Scholar 

  22. Kidambi T, Been MJ, Maddalozzo J (2012) Congenital sialolipoma of the parotid gland: presentation, diagnosis, and management. Am J Otolaryngol 33:279–281

    Article  PubMed  Google Scholar 

  23. Sato K, Gotoh C, Uchida H et al (2011) Sialolipoma of the submandibular gland in a child. J Pediatr Surg 46:408–410

    Article  PubMed  Google Scholar 

  24. Mitsimponas KT, Agaimy A, Schlittenbauer T, Nkenke E, Neukam FW (2012) Oncocytic lipoadenoma of the parotid gland: a report of a new case and review of the literature. Int J Clin Exp Pathol 5:1000–1006

    PubMed Central  PubMed  Google Scholar 

  25. Akrish S, Leiser Y, Shamira D, Peled M (2011) Sialolipoma of the salivary gland: two new cases, literature review, and histogenetic hypothesis. J Oral Maxillofac Surg 69:1380–1384

    Article  PubMed  Google Scholar 

  26. Qayyum S, Meacham R, Sebelik M, Zafar N (2013) Sialolipoma of the parotid gland: case report with literature review comparing major and minor salivary gland sialolipomas. J Oral Maxilofac Pathol 17:95–98

    Article  Google Scholar 

  27. Binmadi NO, Chaisuparat R, Levy BA, Nikitakis NG (2012) Sialolipoma of the lower lip: case report and literature review. Open Dent J 6:208–211

    Article  PubMed Central  PubMed  Google Scholar 

  28. de Moraes M, de Matos FR, de Carvalho CP, de Medeiros AM, de Souza LB (2010) Sialolipoma in minor salivary gland: case report and review of the literature. Head Neck Pathol 4:249–252

    Article  PubMed Central  PubMed  Google Scholar 

  29. Nonaka CF, Pereira KM, de Andrade Santos PP, de Almeida Freitas R, da Costa Miguel MC (2011) Sialolipoma of minor salivary glands. Ann Diagn Pathol 15:6–11

    Article  PubMed  Google Scholar 

  30. de Freitas MA, Freitas VS, de Lima AA, Pereira FB Jr, dos Santos JN (2009) Intraoral lipomas: a study of 26 cases in a Brazilian population. Quintessence Int 40:79–85

    PubMed  Google Scholar 

  31. Arai Y, Katsuyama N, Yokozawa S, Uchida M, Fujita H, Nonaka H (2002) A case of sialolipoma of the palate. Jpn J Oral Maxillofac Surg 48:172–174

    Article  Google Scholar 

  32. Manor E, Sion-Vardy N, Joshua BZ, Bodner L (2011) Oral lipoma: analysis of 58 new cases and review of the literature. Ann Diagn Pathol 15:257–261

    Article  PubMed  Google Scholar 

  33. Miranda Herrera O, Ruiz Rodríguez R, López Noriega JC (2013) Excisión quirúrgica de sialolipoma. Reporte de un caso clínico. Rev Odontol Mexicana 17:121–124

    Google Scholar 

  34. Khazaeni K (2013) Jafarian AH, Khajehahmadi S, Rahpeyma A, Asadi L (2013) Sialolipoma of salivary glands: two case reports and review of the literature. Dent Res J (Isfahan) 10:93–97

    Google Scholar 

Download references

Acknowledgments

This research received no specific grant from any funding agency in the public, commercial, or not for-profit sectors.

Conflict of interest

The authors declare that there is no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Luis Alberto Gaitán Cepeda.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Leyva Huerta, E., Quezada Rivera, D., Tenorio Rocha, F. et al. Sialolipoma of Minor Salivary Glands: Presentation of Five Cases and Review of the Literature with an Epidemiological Analyze. Indian J Otolaryngol Head Neck Surg 67 (Suppl 1), 105–109 (2015). https://doi.org/10.1007/s12070-014-0788-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-014-0788-1

Keywords

Navigation