Abstract
According to WHO, there will be epidemic of diabetes world over and India is going to be ‘A diabetes capital of the world’ by 2025. With the increasing incidence of diabetes, the associated complications are also bound to increase. Rhinocerebral mucormycosis is one of them.
Rhinocerebral Mucormycosis is an opportunistic, fulminating fungal infection, caused by Rhizopus species of order of mucorales, frequently seen in diabetic and immunocompromised patients. Mucormycosis has a very high mortality rate.
Early diagnosis and treatment with Amphotericin-B is the key to combat this disease successfully. We have seen 13 cases in last 3 years (2002–2005) in our area. This incidence is significant, as this type of cases were rarely seen before 2002, in this geographical area. We present an account of these cases; treatment strategies adopted, review of literature, and highlight ‘the role of ENT surgeon in diagnosis and management of this dreadful disease’.
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References
Suneetha Nityanandam, Moire Jacob, Ravindra Battu et.el (2003) Rhino-Orbito-Cerebral Mucormycosis. A retrospective Analysis of Clinical features and Treatment Outcomes. Indian Journal of Ophthalmology; 51: 231–236.
Seiff SR; Choo PH; Carter SR, (1999) Role of local amphotericin B therapy for sino-orbital fungal infections. Ophthalmic Plastic and Reconstructive Surgery, 15(1); 28–31
Jiang Rs, Hsucy. (1999) Endoscopic Sinus Surgery for Rhinocerebral Mucormycosis.. American Journal of Rhinology Mar-Apr 13(2): 105–109
WHO study group. Prevention of diabetes mellitus. Technical report 844. Geneva: WHO 1994
Artis and colleagues,(1982) Diabetes Dec; 31(12): 1109–1146
— Appl Environ Microbiol 1976 Sep;32(3):381–7)
Vaid N S, Athavale S A, Kale OS (2005), Mucormycosis: A retrospective study, Indian Journal of Otolaryngology and Head and Neck Surgery, 57-2: 136–138
Kristin E. Mondy, M.D., Bruce Haughey, M.D., Philip L. Custer, M.D., Franz J. Wippold II, M.D., David J. Ritchie, Pharm D., Linda M. Mundy, M.D (2002) Rhinocerebral Mucormycosis in the Era of Lipid-Based Amphotericin B: Case Report and Literature Review, Pharmacotherapy 22(4): 519–526,.
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This Paper was presented at MENTCON, 2005 Mumbai, and achieved best paper award in consultant category.
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Mane, R.S., Watve, J.K., Mohite, A.A. et al. Rhinocerebral mucormycosis: A deadly disease on the rise. Indian J Otolaryngol Head Neck S 59, 112–115 (2007). https://doi.org/10.1007/s12070-007-0034-1
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DOI: https://doi.org/10.1007/s12070-007-0034-1