Abstract
Bacterial resistance to antibiotics poses a serious challenge to the prospect of chemotherapy. Rational use of antibiotics is most desirable but it cannot provide a permanent solution to the problem. In this article the biochemical and genetic basis of antibiotic resistance in bacteria is discussed with examples. The non-clinical aspects of antibiotic-resistance are also dealt with in brief.
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Saswati Sengupta is a reserach associate at the Indian Institute of Chemical Technology (CSIR). Her areas of interest are therapeutic proteins and intellectual property rights.
Madhab K Chattopadhyay is a scientist at the Centre for Cellular and Molecular Biology (CSIR). His areas of interest are stress adaptation of bacteria and antibiotic resistance in microorganisms.
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Sengupta, S., Chattopadhyay, M.K. Antibiotic resistance of bacteria: A global challenge. Reson 17, 177–191 (2012). https://doi.org/10.1007/s12045-012-0017-8
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DOI: https://doi.org/10.1007/s12045-012-0017-8