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Sulfamic acid as energy efficient catalyst for synthesis of flurophores, 1-H-spiro [isoindoline-1,2′-quinazoline]-3,4′(3′H)-diones

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Abstract

An energy efficient synthesis of 1-H-spiro[isoindoline-1,2 ′-quinazoline]-3,4 ′(3 ′ H)-diones has been expediently accomplished by a reaction of isatin(s) / cyclic ketone and anthranilamide in ethanol at ambient temprature. Excellent yields of the products in short time duration, operational simplicity, and simple work-up procedure are the attractive features of the present protocol. Synthesized 1-H-spiro[isoindoline-1,2 ′-quinazoline]-3,4 ′(3 ′ H)-diones were found to be fluorescent with absorption in UV region (302, 362 nm) and emission in visible region (413-436 nm) with Stokes shift of 44-72 nm.

Synthesis of 1-H-spiro [isoindoline-1,2’-quinazoline]-3,4’(3’H)-diones

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Acknowledgements

Authors DMP and MMM are thankful to UGC, New Delhi for financial assistance [F. No.42-394/2013 (SR)] and teacher fellowship under FDP [F.No-36-50/11WRO 30/12/2012], respectively.

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Authors and Affiliations

  1. Department of Chemistry, Shivaji University, Kolhapur, 416 004, India

    MANSING M MANE & DATTAPRASAD M PORE

Authors
  1. MANSING M MANE
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  2. DATTAPRASAD M PORE
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Correspondence to DATTAPRASAD M PORE.

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Supplementary Information (SI)

Experimental details, procedures and spectral data viz., IR, 1H, 13C NMR and Mass spectra of synthesized compounds are provided as supplementary file. Supplementary information is available at www.ias.ac.in/chemsci.

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MANE, M.M., PORE, D.M. Sulfamic acid as energy efficient catalyst for synthesis of flurophores, 1-H-spiro [isoindoline-1,2′-quinazoline]-3,4′(3′H)-diones. J Chem Sci 128, 657–662 (2016). https://doi.org/10.1007/s12039-016-1047-7

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  • DOI: https://doi.org/10.1007/s12039-016-1047-7

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