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Fe(HSO 4 ) 3 : An efficient, heterogeneous and reusable catalyst for C-alkylation of β-dicarbonyl compounds

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Abstract

Fe(HSO4)3(FHS) was used as an efficient catalyst for the heterogeneous addition of a series of benzylic and allylic alcohols to various β-dicarbonyl compounds, which afforded moderate to excellent yields of C-alkylated products in 1,2-dichloroethane. In comparison with the previous methods, the present research surprisingly exhibited higher reaction yields without formation of any by-products which could be formed by self-condensation of alcohols. Moreover, the catalyst can be readily recovered and reused up to five times with almost maintained reactivity and yields.

Fe(HSO4)3 was applied as an efficient catalyst for addition of alcohols to β-dicarbonyl compounds, which afforded excellent yields of C-alkylated products. In comparison with the previous methods, the present method shown higher reaction yields without formation of any by-products. Moreover, the catalyst can be readily recovered and reused.

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Acknowledgements

The authors thank the Ferdowsi University of Mashhad Research Council (Grant no. p/3/24394) for partial financial support.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, 9177948974, Iran

    SAMANEH KHAFAJEH, BATOOL AKHLAGHINIA, SOODABEH REZAZADEH & HOSSEIN ESHGHI

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  1. SAMANEH KHAFAJEH
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  2. BATOOL AKHLAGHINIA
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  3. SOODABEH REZAZADEH
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  4. HOSSEIN ESHGHI
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Correspondence to BATOOL AKHLAGHINIA.

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KHAFAJEH, S., AKHLAGHINIA, B., REZAZADEH, S. et al. Fe(HSO 4 ) 3 : An efficient, heterogeneous and reusable catalyst for C-alkylation of β-dicarbonyl compounds. J Chem Sci 126, 1903–1912 (2014). https://doi.org/10.1007/s12039-014-0630-z

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  • DOI: https://doi.org/10.1007/s12039-014-0630-z

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