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Green and solvent-free procedure for microwave-assisted synthesis of 2,4,6-triarylpyridines catalysed using MgAl2O4 nanocrystals

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Abstract

Design and development of a heterogeneous nanocatalyst for condensation reaction of acetophenone derivatives, aromatic aldehydes, and ammonium acetate to yield 2,4,6-triarylpyridines followed by microwave irradiation is described. Nanocrystalline MgAl2O4 as a novel heterogeneous recyclable catalyst shows high activity for the above reaction. In addition, the easily recoverable nanosized catalysts showed good reusability.

The design of a heterogeneous nanocatalyst for condensation reaction of acetophenone derivatives, aromatic aldehydes, and ammonium acetate to yield 2,4,6-triarylpyridines followed by microwave irradiation is described here. Nanocrystalline MgAl2O4 as a novel heterogeneous, recyclable catalyst shows high activity for the above reaction.

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Acknowledgement

The authors gratefully acknowledge the financial support from the Research Council of the University of Kashan (Grant No. 256722/17), Iran.

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Authors and Affiliations

  1. Laboratory of Organic Chemistry Research, Department of Chemistry, College of Chemistry, University of Kashan, Kashan, P.O. Box: 87317-51167, Kashan, Islamic Republic of Iran

    JAVAD SAFARI, SOHEILA GANDOMI-RAVANDI & MAHMOUD BORJIAN BORUJENI

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  1. JAVAD SAFARI
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  2. SOHEILA GANDOMI-RAVANDI
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  3. MAHMOUD BORJIAN BORUJENI
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Correspondence to JAVAD SAFARI.

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SAFARI, J., GANDOMI-RAVANDI, S. & BORUJENI, M.B. Green and solvent-free procedure for microwave-assisted synthesis of 2,4,6-triarylpyridines catalysed using MgAl2O4 nanocrystals. J Chem Sci 125, 1063–1070 (2013). https://doi.org/10.1007/s12039-013-0477-8

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  • DOI: https://doi.org/10.1007/s12039-013-0477-8

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