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Diethylamine functionalized polyethylene glycol as a novel and efficient catalyst for Knoevenagel condensation

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Abstract

The Knoevenagel condensation of aromatic aldehydes with active methylene is an efficient reaction for carbon–carbon double bond formation. A rapid, efficient, and ecofriendly protocol for the Knoevenagel condensation of active methylene compounds with aldehydes has been developed with diethylamine functionalized polyethylene glycol-600 (PEG-600) as catalyst with good to excellent yields at room temperature without solvent.

Diethylamine functionalized polyethylene glycol-600 (PEG-600) catalyses the Knoevenagel condensation of active methylene compounds with aldehydes with good to excellent yields at room temperature without a solvent.

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Authors and Affiliations

  1. College of Science, Huazhong Agricultural University, Wuhan, Hubei 430070, China

    WEN YE, HONG JIANG & XIAN-CAO YANG

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  1. WEN YE
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  2. HONG JIANG
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  3. XIAN-CAO YANG
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Correspondence to HONG JIANG.

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YE, W., JIANG, H. & YANG, XC. Diethylamine functionalized polyethylene glycol as a novel and efficient catalyst for Knoevenagel condensation. J Chem Sci 123, 331–334 (2011). https://doi.org/10.1007/s12039-011-0085-4

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  • DOI: https://doi.org/10.1007/s12039-011-0085-4

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