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Synthesis of novel spiro-β-lactams

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Abstract

A new synthetic approach for spiro-β-lactams by cyclization of cis-3-allyl-3-benzylthio-β-lactams is presented. The reaction involves step-wise electrophilic addition-dealkylation sequence giving stereospecific synthesis of C-3-spiro-β-lactams.

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Authors and Affiliations

  1. Department of Chemistry and Centre of Advanced studies in chemistry, Panjab University, Chandigarh, 160 014, India

    Renu Arora, P. Venugopalan & S. S. Bari

Authors
  1. Renu Arora
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  2. P. Venugopalan
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  3. S. S. Bari
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Corresponding author

Correspondence to S. S. Bari.

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Arora, R., Venugopalan, P. & Bari, S.S. Synthesis of novel spiro-β-lactams. J Chem Sci 122, 125–135 (2010). https://doi.org/10.1007/s12039-010-0013-z

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  • DOI: https://doi.org/10.1007/s12039-010-0013-z

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