Skip to main content
Log in

One-pot synthesis of quinaldine derivatives by using microwave irradiation without any solvent — A green chemistry approach

  • Published:
Journal of Chemical Sciences Aims and scope Submit manuscript

Abstract

A convenient and efficient procedure for synthesis of quinaldine derivatives has been developed by a simple one-pot reaction of aniline derivatives and acetaldehyde on the surface of neutral alumina impregnated with hydrochloric acid under microwave irradiation without any solvent according to green chemistry.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Elguero J 1984 Comprehensive heterocyclic chemistry (ed.) A McKillop (Oxford: Pergamon Press) Vol. 5, p. 167

    Google Scholar 

  2. Penning T D, Talley J J, Bertenshaw S R, Carter J S, Colins P W, Graneton J M, Lee L F and Malecha J W 1997 J. Med. Chem. 40 1347

    Article  CAS  Google Scholar 

  3. Menozzi G, Mosti L, Fossa P, Maltioli F and Ghia M 1997 J. Heterocycl. Chem. 34 963

    Article  CAS  Google Scholar 

  4. Naik R D and Desai K R 1998 Orient. J. Chem. 14 161

    CAS  Google Scholar 

  5. Kidwai M and Negi N 1997 Monatsh. Chem. 128 85

    Article  CAS  Google Scholar 

  6. El-Sayed O A, El-Bieh F B, El-Aqeel S I, Al-Bassam B A and Hussein M E 2002 Bull. Chim. Farm. 141 461

    CAS  Google Scholar 

  7. Selvi S T, Nadaraj V, Mohan S, Sasi R and Hema M 2006 Bioorg. Ed. Chem. 14 3896

    Article  CAS  Google Scholar 

  8. Jashi A A, Narkhede S S and Viswanathan C L 2005 Bioorg. Med. Chem. Lett. 15 73

    Article  CAS  Google Scholar 

  9. Suresh T, Nandha Kumar R, Magesh S and Mohan P S 2003 Indian J. Chem. B42 2133

    Google Scholar 

  10. Suresh T, Nandha Kumar R, Magesh S and Mohan P S 2003 Indian J. Chem. B42 688

    Google Scholar 

  11. Skraup H 1880 Chem. Ber. 13 2086

    Google Scholar 

  12. Doebner O and Miller W 1883 Bericht. 16 2464

    Google Scholar 

  13. Friedlander P 1882 Chem. Ber. 15 2572

    Article  Google Scholar 

  14. Hall N 1994 Science 266 32

    Article  CAS  Google Scholar 

  15. Loupy A, Petit A, Hamelin J, Texier-Boullet F, Jacquault P and Mathe D 1998 Synthesis 2113

  16. Perreux L and Loupy A 2001 Tetrahedron 57 9199

    Article  CAS  Google Scholar 

  17. Lindstroem P, Tierney J, Wathey B and Westman J 2001 Tetrahedron 57 9225

    Article  Google Scholar 

  18. Varma R S 1999 Green Chem. 43

  19. Kim J K, Kwon P S, Kwon T W, Chung S K and Lee J W 1996 Synth. Commun. 26 535

    Article  CAS  Google Scholar 

  20. Kim S Y, Kwon P S, Kwon T W, Chung S K and Chang Y T 1997 Synth. Commun. 27 533

    Article  Google Scholar 

  21. Kwon P S, Kim Y S, Kang C J, Kwon T W, Chung S K and Chang Y T 1997 Synth. Commun. 27 4091

    Article  CAS  Google Scholar 

  22. Manske R H F 1942 Can. J. 20 133

    Google Scholar 

  23. Minkin V I 1961 Chem. Abs. 55 14457

    Google Scholar 

  24. Hamer F M 1921 J. Chem. Soc. 119 1432

    CAS  Google Scholar 

  25. Neumann M 1946 Org. Synth. 26 47

    Google Scholar 

  26. Buu-Hoi N P 1948 J. Chem. Soc. 106 110

    Google Scholar 

  27. Denmark S E and Venkatraman S 2006 J. Org. Chem. 71 1668

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Javad Safari.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Safari, J., Banitaba, S.H. & Samiei, S.S. One-pot synthesis of quinaldine derivatives by using microwave irradiation without any solvent — A green chemistry approach. J Chem Sci 121, 481–484 (2009). https://doi.org/10.1007/s12039-009-0057-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12039-009-0057-0

Keywords

Navigation