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References
Barrangou R, Frenaux C, Deveau H, Richards M, Boyaval P, et al. 2007 CRISPR provides acquired resistance against viruses in prokaryotes. Science 315 1709–1712
Bhaya D, Davison M and Barrangou R 2011 CRISP-Cas systems in bacteria and archaea: versatile small RNAs for adaptive defense and regulation. Annu. Rev. Genet. 45 273–297
Brouns SJJ, Jore MM, Lundgren M, Westra ER, Slijkhuis RJH, et al. 2008 Small CRISPR RNAs guide antiviral defense in prokaryotes. Science 321 960–964
Carroll D 2008 Progress and prospects: zinc-finger nucleases as gene therapy agents. Gene Ther. 15 1463–1468
Charpentier E and Doudna JA 2013 Rewriting a genome. Nature 495 50–51
Cho SW, Kim S, Kim JM and Kim J-S 2013 Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat. Biotechnol. 31 230–232
Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, et al. 2010 Targeting DNA double-strand breaks with TAL effector nucleases. Genetics 186 757–761
Cong L, Rann FA, Cox D, Lin S, Barretto R, et al. 2013 Multiplex genome engineering using CRISPR/cas systems. Science 339 819–823
Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, et al. 2011 CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature 471 602–607
Deveau H, Garneau JE and Moineau S 2010 CRISPR/cas system and its role in phage-bacteria interactions. Annu. Rev. Microbiol. 64 475–493
Doudna JA and Charpentier E 2014 The new frontier of genome engineering with CRISPR-Cas9. Science 346 1077
Garneau JE, Dupuis M-E, Villion M, Romero DA, Barrangou R, et al. 2010 The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature 468 67–71
Gasiunas G, Barrangou R, Horvath P and Siksnys V 2012 Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc. Natl. Acad. Sci. USA 109 E2579–E2586
Gottesman S 2011 Dicing defence in bacteria. Nature. 471 588–589
Hale CR, Zhao P, Olson S, Duff MO, Graveley BR, et al. 2009 RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex. Cell 139 945–956
Horvath P and Barrangou R 2010 CRISPR/Cas, the immune system of bacteria and archaea. Science 327 167–170
Hwang WY, Fu Y, Reyon D, Maeder ML, Tsai SQ, et al. 2013 Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat. Biotechnol. 31 227–229
Jacquier A and Dujon B 1985 An intron-encoded protein is active in a gene conversion process that spreads an intron into a mitochondrial gene. Cell 41 383–394
Jiang W, Bikard D, Cox D, Zhang F and Marraffini LA 2013 RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat. Biotechnol. 31 233–239
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA and Charpentier E 2012 A programmable Dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337 816–821
Makarova KS, Grishin NV, Shabalina SA, Wolf YI and Koonin EV 2006 A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action. Biol. Direct. 1 7
Makarova KS, Haft DH, Barrangou R, Brouns SJJ, Charpentier E, et al. 2011 Evolution and classification of the CRISPR-Cas systems. Nat. Rev. Microbiol. 9 467–477
Mali P, Yang L, Esvelt KM, Aach J, Guelt M, et al. 2013 RNA-guided human genome engineering via Cas9. Science. 339 823–826
Marraffini LA and Sontheimer EJ 2008 CRISPR interference limits horizontal gene transfer in Staphylococci by targeting DNA. Science 322 1843–1845
Marraffini LA and Sontheimer EJ 2010 CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea. Nat. Rev. Genet. 11 181–190
Miller JC, Tan S, Qiao G, Barlow KA, Wang J, et al. 2011 A TALE nuclease architecture for efficient genome editing. Nat. Biotechnol. 29 143–148
Morange M 2015 CRISPR-Cas: the discovery of an immune system in prokaryotes. J. Biosci. 40 1–3
Pennisi E 2013 The CRISPR craze. Science 341 833–836
Perez EE, Wang J, Miller JC, Jouvenot Y, Kim KA, et al. 2008 Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat. Biotechnol. 26 808–816
Sapranauskas R, Gasiunas G, Fremaux C, Barrangou R, Horvath P and Siksnys V 2011 The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli. Nucleic Acids Res. 39 9275–9282
Urnov FD, Rebar EJ, Holmes MC, Zhang HS and Gregory PD 2010 Genome editing with engineered zinc finger nucleases. Nat. Rev. Genet. 11 636–646
Van der Oost J, Jore MM, Westra ER, Lundgren M and Brouns SJJ 2009 CRISPR-based adaptive and heritable immunity in prokaryotes. Trends Biochem. Sci. 34 401–407
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, et al. 2013 One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153 910–918
Waters LS and Storz G 2009 Regulatory RNAs in bacteria. Cell 136 615–628
Wiedenheft B, Sternberg SH and Doudna JA RNA-guided genetic silencing systems in bacteria and archaea. Nature 482 331–338
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I am indebted to David Marsh for his critical reading of the manuscript, and to Stuart Newman for his very helpful remarks.
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Morange, M. What history tells us XXXIX. CRISPR-Cas: From a prokaryotic immune system to a universal genome editing tool. J Biosci 40, 829–832 (2015). https://doi.org/10.1007/s12038-015-9575-8
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DOI: https://doi.org/10.1007/s12038-015-9575-8