References
Adhikari P, Bacchawat-Sikder K, Thomas C J, Ravishankar R, Jeyaprakash A A, Sharma V, Vijayan M and Surolia A 2001 Mutational analysis at N41 in peanut agglutinin (PNA): A residue critical for binding of the tumor-associated Thomsen-Friedenreich antigen; J. Biol. Chem. 276 40734–40739
Banerjee R, Das K, Ravishankar R, Suguna K, Surolia A and Vijayan M 1996 Conformation, protein-carbohydrate interactions and a novel subunit association in the refined structure of peanut lectin-lactose complex; J. Mol. Biol. 259 281–296
Banerjee R, Mande S C, Ganesh V, Das K, Dhanaraj V, Mahanta S K, Suguna K, Surolia A and Vijayan M 1994 Crystal structure of peanut lectin, a protein with an unusual quaternary structure; Proc. Natl. Acad. Sci. USA 91, 227–231
Chandra N R, Prabu M M, Suguna K and Vijayan M 2001 Structural similarity and functional diversity in proteins containing the legume lectin fold; Protein Eng. 14 857–866
Chandra N R, Ramachandraiah G, Bachhawat K, Dam T K, Surolia A and Vijayan M 1999 Crystal structure of a dimeric mannose specific agglutinin from garlic: Quaternary association and carbohydrate specificity; J. Mol. Biol. 285 1157–1168
Jeyaprakash A A, Jayashree G, Mahanta S K, Swaminathan C P, Sekar K, Surolia A and Vijayan M 2005 Structural basis for the energetics of jacalin-sugar interactions: Promiscuity versus specificity; J. Mol. Biol. 347 181–188
Jeyaprakash A A, Srivastav A, Surolia A and Vijayan M 2004 Structural basis for the carbohydrate specificities of artocarpin. Variation in the length of a loop as a strategy for generating ligand specificity; J. Mol. Biol. 338 757–770
Kulkarni K A, Srivastav A, Mitra N, Sharon N, Surolia A, Vijayan M and Suguna K 2004 Effect of glycosylation on the structure of Erythrina corallodendron lectin; PROTEINS: Struct. Funct. Bioinformat. 56 821–827
Lis H and Sharon N 1998 Lectins: carbohydrate-specific proteins that mediate cellular recognition; Chem. Rev. 98 637–674
Manoj N, Srinivas V R, Surolia A and Suguna K 2000 Carbohydrate specificity and salt bridge mediated conformational change in acidic winged bean agglutinin; J. Mol. Biol. 302 1129–1137
Natchiar K S, Jeyaprakash A A, Ramya T N C, Thomas C J, Suguna K, Surolia A and Vijayan M 2004 Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure; Acta Crystlogr. D60 211–219
Natchiar K S, Srinivas O, Mitra N, Sagarika Dev, Jayaraman N, Surolia A and Vijayan M 2006a Multivalency in lectins. A crystallographic, modelling and light scattering study involving peanut lectin and a bivalent ligand; Curr. Sci. 90 1230–1237
Natchiar K S, Srinivas O, Mitra N, Surolia A, Jayaraman N and Vijayan M 2006b Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin; Acta Crystalogr. D62 1413–1421
Natchiar K S, Suguna K, Surolia A and Vijayan M 2007 Peanut agglutinin, a lectin with an unusual quaternary structure and interesting ligand binding properties; Cryst. Rev. 13 1–26
Prabu M M, Sankaranarayanan R, Puri K D, Sharma V, Surolia A, Vijayan M and Suguna K 1998 Carbohydrate specificity and quaternary association in basic winged bean lectin; J. Mol. Biol. 276 787–796
Prabu M M, Suguna K and Vijayan M 1999 Variability in quaternary association of proteins with the same tertiary fold. A case study and rationalisation involving legume lectins; Proteins: Struct. Funct. Genet. 35 58–69
Pratap J V, Bradbrook G M, Reddy G B, Surolia A, Raffery J, Helliwell J R and Vijayan M 2001 The combination of molecular dynamics with crystallography for elucidating protein-ligand interactions. A case study involving peanut lectin complexes with T-antigen and lactose; Acta Crystalogr D57 1584–1594
Pratap J V, Jeyaprakash A A, Geetha Rani P, Sekar K, Surolia A and Vijayan M 2002 Crystal structure of artocarpin, a Moraceae lectin with mannose specificity, and its complex with methyl-α-D-mannose. Implications to the generation of carbohydrate specificity; J. Mol. Biol. 317 237–247
Ramachandraiah G, Chandra N R, Surolia A and Vijayan M 2003 Computational analysis of multivalency of Lectins: Structures of garlic lectin-oligosachharide complexes and their aggregates; Glycobiology 13 765–775
Ravishankar R, Ravindran M, Suguna K, Surolia A and Vijayan M 1997 Crystal structure of the peanut lectin-T-antigen complex. Carbohydrate specificity generated by water bridges; Curr. Sci. 72 855–861
Ravishankar R, Suguna K, Surolia A and Vijayan M 1999 The crystal structures of the complexes of peanut lectin with methyl-β-Galactose and N-acetylactosamine and a comparative study of carbohydrate binding in Gal/GalNac specific legume lectins; Acta Crystalogy D55 1375–1382
Salunke D M, Islam Khan M, Surolia A and Vijayan M 1982 Crystallization and preliminary X-ray studies of the anti-T lectin from peanut (Arachis hypogaea); J. Mol. Biol. 154 177–178
Sankaranarayanan R, Sekar K, Banerjee R, Sharma V, Surolia A and Vijayan M 1996 A novel mode of carbohydrate recognition in jacalin, a Moraceae plant lectin with a β prism fold; Nat. Struct. Biol. 3 596–603
Singh D D, Saikrishnan K, Prashant Kumar, Sekar K, Surolia A and Vijayan M 2005 Unusual sugar specificity of banana lectin from Musa paradisiaca and its probable evolutionary origin. Crystallographic and modelling studies; Glycobiology 15 1025–1032
Vijayan M and Chandra N R 1999 Lectins; Curr. Opin. Struct. Biol. 9 707–714
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Vijayan, M. Peanut lectin crystallography and macromolecular structural studies in India. J. Biosci. 32 (Suppl 2), 1059–1066 (2007). https://doi.org/10.1007/s12038-007-0108-y
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12038-007-0108-y