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Sequence and recombination analyses of the geminivirus replication initiator protein

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Abstract

The sequence motifs present in the replication initiator protein (Rep) of geminiviruses have been compared with those present in all known rolling circle replication initiators. The predicted secondary structures of Rep representing each group of organisms have been compared and found to be conserved. Regions of recombination in the Rep gene and the adjoining 5′ intergenic region (IR) of representative species of Geminiviridae have been identified using Recombination Detection Programs. The possible implications of such recombinations on the increasing host range of geminivirus infections are discussed.

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Abbreviations

RCR:

Rolling circle replication

RDP:

Recombination Detection Program

Rep:

replication initiator protein

TYLCV:

Tomato yellow leaf curl virus-Sardinia

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Authors and Affiliations

  1. Center for Excellence in Bioinformatics, Madurai Kamaraj University, Madurai, 625 021, India

    T Vadivukarasi

  2. Department of Plant Biotechnology, School of Biotechnology, Madurai Kamaraj University, Madurai, 625 021, India

    K R Girish & R Usha

Authors
  1. T Vadivukarasi
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  2. K R Girish
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  3. R Usha
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Correspondence to R Usha.

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Vadivukarasi, T., Girish, K.R. & Usha, R. Sequence and recombination analyses of the geminivirus replication initiator protein. J Biosci 32, 17–29 (2007). https://doi.org/10.1007/s12038-007-0003-6

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  • DOI: https://doi.org/10.1007/s12038-007-0003-6

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