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Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials

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Abstract

Adenocarcinomas of the lower oesophagus and gastro-oesophageal junction are a complex clinico-pathological setting. Multimodality therapy is considered mandatory in most disease presentations. Nevertheless, the most appropriate treatment package has yet to be established. We herein summarize the evidence derived from randomized phase III trials on pre-operative treatments in this oncological scenario.

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Authors and Affiliations

  1. Department of Oncology, Radiation Oncology, University of Turin, Via Genova 3, 10126, Turin, Italy

    Pierfrancesco Franco, Francesca Arcadipane, Elisabetta Trino, Stefania Martini, Giuseppe Carlo Iorio & Umberto Ricardi

  2. Department of Surgical Sciences, General Surgery 2U and Liver Transplantation Center, University of Turin, Turin, Italy

    Paolo Strignano & Renato Romagnoli

  3. Department of Oncology, Medical Oncology 1, AOU Citta’ della Salute e della Scienza, Turin, Italy

    Rosella Spadi

  4. Department of Oncology, Medical Oncology 1, University of Turin, Turin, Italy

    Maria Antonietta Satolli

  5. Department of Oncology, Medical Oncology 2, AOU Citta’ della Salute e della Scienza, Turin, Italy

    Mario Airoldi

  6. Department of Surgical Sciences, General Surgery 1U, University of Turin, Turin, Italy

    Michele Camandona

Authors
  1. Pierfrancesco Franco
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  2. Francesca Arcadipane
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  3. Paolo Strignano
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  5. Elisabetta Trino
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  6. Stefania Martini
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  7. Giuseppe Carlo Iorio
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  8. Maria Antonietta Satolli
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  9. Mario Airoldi
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  10. Renato Romagnoli
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  11. Michele Camandona
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  12. Umberto Ricardi
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Correspondence to Pierfrancesco Franco.

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Franco, P., Arcadipane, F., Strignano, P. et al. Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials. Med Oncol 34, 40 (2017). https://doi.org/10.1007/s12032-017-0898-1

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  • DOI: https://doi.org/10.1007/s12032-017-0898-1

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