Abstract
Tumor lysis syndrome (TLS) is a potential emergent complication of oncologic treatment. TLS is commonly reported in hematological malignancies with rapid cell turnover rates, but is relatively rare in solid tumors. TLS is most frequently a result of cancer treatment in combination with a large tumor burden, but has occasionally been reported to occur spontaneously, especially in cases of advanced or metastatic disease. In this article, we describe the case of a patient with newly diagnosed metastatic melanoma that developed TLS two days after initiation of corticosteroids. In addition, we present a brief literature review of melanoma-associated TLS and review the etiology, diagnosis, and management of TLS.
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Meeks, M.W., Hammami, M.B., Robbins, K.J. et al. Tumor lysis syndrome and metastatic melanoma. Med Oncol 33, 134 (2016). https://doi.org/10.1007/s12032-016-0854-5
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DOI: https://doi.org/10.1007/s12032-016-0854-5