Abstract
Angiosarcomas are a relatively rare histological subtype of sarcomas and represent <1% of all sarcomas. Prostate angiosarcoma is extremely rare and displays remarkable clinical and pathological heterogeneity. Despite the rarity, it usually presents with dysuria, hematuria, or pelvic pain and represents a treatment challenge. Only nine cases have been reported in the literature, and we report the 10th case of prostate angiosarcoma and the first case of prostate angiosarcoma with recurrent adenocarcinoma.
References
Schoen FJ, Mitchell NR. Blood vessels. In: Kumar V, Abbas AK, Fausto N, Aster JC, editors. Robbins and Cotran pathologic basis of disease. 8th ed. Philadelphia: W.B. Saunders Company; 2009. p. 487–527.
Smith DM, Manivel C, Kapps D, Uecker. Angiosarcoma of the prostate: report of 2 cases and review of the literature. J Urol. 1986;135:382–4.
Botesco M. Sarcome primitif de la prostate chez un enfant de deux ans et neuf mois. Bull Mem Soc Chir Bucarest. 1902;5:77.
Salleras J, Vilar G. Consideraciones a proposito de un sarcoma primitivo de la prostata en un sujeto de 32 anos prostatectomia perineal. Semana Med Buenos Aires. 1924;31:1275.
Chan KW. Angiosarcoma of the prostate. An immunohistochemical study of a case. Pathology. 1990;22:108–10.
Oliva Encina J, Gil Martinez P, Allepuz Losa C, Andrés Lázaro V, Rioja Sanz LA. Prostatic angiosarcoma: report of a new case. Actas Urol Esp. 2001;25(1):78–80.
Chandan VS, Wolsh L. Postirradiation angiosarcoma of the prostate. Arch Pathol Lab Med. 2003;127:876–8.
Lee HM, Song SY, Park JO, Kim BH. Primary immature teratoma of the prostate with angiosarcoma component: its unusual response to chemotherapy. Int J Urol. 2006;13:305–7.
Guo CC, Pisters LL, Troncoso P. Prostate cancer invading the rectum: a clinicopathological study of 18 cases. Pathology. 2009;41:539–43.
Cahan WG, Woodard HQ, Higinbotham NL, Stewart FW, Coley BL. Sarcoma arising in irradiated bone. Cancer. 1948;1:3–29.
Nanus DM, Kelsen D, Clark DG. Radiation-induced angiosarcoma. Cancer. 1987;60(4):777–9.
Navon JD, Rahimzadeh M, Wong AK, Carpenter PM, Ahlering TE. Angiosarcoma of the bladder after therapeutic irradiation for prostate cancer. J Urol. 1997;157(4):1359–60.
Koch M, Nielsen GP, Yoon SS. Malignant tumors of blood vessels: angiosarcomas, hemangioendotheliomas, and hemangioperictyomas. J Surg Oncol. 2008;97(4):321–9.
Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ. Angiosarcoma. Lancet Oncol. 2010;11(10):983–91.
Fury MG, Antonescu CR, Van Zee KJ, Brennan MF, Maki RG. A 14-year retrospective review of angiosarcoma: clinical characteristics, prognostic factors, and treatment outcomes with surgery and chemotherapy. Cancer J. 2005;11:241–7.
Fayette J, Martin E, Piperno-Neumann S, Le Cesne A, Robert C, Bonvalot S, et al. Angiosarcomas, a heterogeneous group of sarcomas with specific behavior depending on primary site: a retrospective study of 161 cases. Ann Oncol. 2007;18:2030–6.
Abraham JA, Hornicek FJ, Kaufman AM, Harmon DC, Springfield DS, Raskin KA, et al. Treatment and outcome of 82 patients with angiosarcoma. Ann Surg Oncol. 2007;14:1953–67.
Pawlik TM, Paulino AF, McGinn CJ, Baker LH, Cohen DS, Morris JS, et al. Cutaneous angiosarcoma of the scalp: a multidisciplinary approach. Cancer. 2003;98:1716–26.
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The authors would like to acknowledge Regina Landis and Sharon Davis-Devine for their assistance with manuscript preparation.
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Khaliq, W., Meyer, C.F., Uzoaru, I. et al. Prostate angiosarcoma: a case report and literature review. Med Oncol 29, 2901–2903 (2012). https://doi.org/10.1007/s12032-012-0188-x
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DOI: https://doi.org/10.1007/s12032-012-0188-x