Skip to main content

Advertisement

Log in

Successful treatment of chronic hiccup with baclofen in cancer patients

  • Case Report
  • Published:
Medical Oncology Aims and scope Submit manuscript

Abstract

Chronic hiccup is an infrequent but distressing symptom in patients with advanced cancer. A series of drugs (chlorpromazine, haloperidol, nifedipine, metoclopramide, baclofen) have been used to treat hiccup without definitive results. Some authors have suggested a possible role of baclofen in the treatment of chronic hiccup. We report three cases of chronic hiccup in patients with cancer successfully treated with baclofen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Marinella MA. Diagnosis and management of hiccups in the patient with advanced cancer. J Support Oncol. 2009;7(4):122–7, 130.

    Google Scholar 

  2. Takiguchi Y, Watanabe R, Nagao K, Kuriyama T. Hiccups as an adverse reaction to cancer chemotherapy. J Natl Cancer Inst. 2002;94(10):772.

    Article  PubMed  CAS  Google Scholar 

  3. Porzio G, Aielli F, Verna L, Aloisi P, Galletti B, Ficorella C. Gabapentin in the treatment of hiccups in patients with advanced cancer: a 5-year experience. Clin Neuropharmacol. 2010;33(4):179–80.

    Article  PubMed  CAS  Google Scholar 

  4. Tay SS, Yadav RR. Novel use of baclofen in cancer patients for the treatment of hiccups. Ann Acad Med Singap. 2010;39(2):154.

    PubMed  Google Scholar 

  5. Guelaud C, Similowski T, Bizec JL, Cabane J, Whitelaw WA, Derenne JP. Baclofen therapy for chronic hiccup. Eur Respir J. 1995;8(2):235–7.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sercan Aksoy.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Şeker, M.M., Aksoy, S., Özdemir, N.Y. et al. Successful treatment of chronic hiccup with baclofen in cancer patients. Med Oncol 29, 1369–1370 (2012). https://doi.org/10.1007/s12032-011-9910-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12032-011-9910-3

Keywords

Navigation