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Primary Squamous Cell Carcinoma of the Stomach: a Case Report

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Abstract

Background

Pure squamous cell carcinoma of the stomach is an extremely rare finding with a worldwide incidence of 0.04 – 0.07% (2).

Methods

We present the case of a 78-year-old female who presented with a right hip fracture and was found to have worsening post-prandial vomiting and weight loss.

Results

Esophagogastroscopy showed a 1.5 cm tumor located along the lesser curvature of the stomach. Endoscopic biopsy specimens of the tumor demonstrated primary squamous cell carcinoma. A workup for an extragastric squamous cell primary source was negative.

Conclusions

The origin of pure squamous cell carcinoma of the stomach has not been well elucidated and thus several plausible theories have been proposed. In the presented case, the patient had a long standing history of gastric erosions and the tumor was adjacent to significant inflammatory mucosa. Therefore, it may be considered that the tumor arises from squamous metaplasia secondary to chronic mucosal damage.

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Acknowledgement

The authors would like to thank Dr. Margaret Yungbluth (Department of Pathology, St. Francis Hospital, Evanston IL) for her help in pathologic analysis.

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Authors and Affiliations

  1. Department of Gastroenterology, St. Francis Hospital, 355 Ridge Ave, Evanston, IL, 60202, USA

    Harsh Gupta

  2. Department of Radiology, Loyola University, 2160 First Ave, Maywood, IL, 60153, USA

    Krishna Amuluru

Authors
  1. Krishna Amuluru
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  2. Harsh Gupta
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Corresponding author

Correspondence to Krishna Amuluru.

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Amuluru, K., Gupta, H. Primary Squamous Cell Carcinoma of the Stomach: a Case Report. J Gastrointest Canc 41, 24–26 (2010). https://doi.org/10.1007/s12029-009-9097-4

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  • DOI: https://doi.org/10.1007/s12029-009-9097-4

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