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Neurologist Versus Machine: Is the Pupillometer Better than the Naked Eye in Detecting Pupillary Reactivity

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Abstract

Background

A 62-year-old man with severe traumatic brain injury developed postsurgical anisocoria in which there was a discrepancy between pupillometer and manual testing.

Methods

Case report.

Results

The patient’s larger pupil was read as unreactive by the pupillometer but constricted 1 mm over 7–9 s of continuous light stimulation.

Conclusions

While pupillometry assessment is a valuable adjunct to the manual pupillary assessment, this case demonstrates that nonreactive pupils read on the pupillometer should be confirmed with the manual examination because it can miss very slowly reacting pupils.

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References

  1. Walters BC et al. Early indicators of prognosis in severe traumatic brain injury. Brain Trauma Foundation Guidelines 2000; 186–198.

  2. Wijdicks EFM, Hijdra A, Young GB, Bassetti CL, Wiebe S. Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2006;67:203–10.

    Article  PubMed  CAS  Google Scholar 

  3. Fugate JE, Wijdicks EFM, Mandrekar J, et al. Predictors of neurologic outcome in hypothermia after cardiac arrest. Ann Neurol. 2010;68:907–14.

    Article  PubMed  Google Scholar 

  4. Bushnell CD, Phillips-Bute BG, Laskowitz DT, Lynch JR, Chilukuri V, Borel CO. Survival and outcome after endotracheal intubation for acute stroke. Neurology. 1999;52:1374–81.

    Article  PubMed  CAS  Google Scholar 

  5. Wijdicks EFM, Bamlet WR, Maramattom BV, Manno EM, McClelland RL. Validation of a new coma scale: the FOUR score. Ann Neurol. 2005;58:585–93.

    Article  PubMed  Google Scholar 

  6. Wijdicks EFM, Varelas PN, Gronseth FS, et al. Evidence-based guideline update: determining brain death in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2010;74:1911–8.

    Article  PubMed  Google Scholar 

  7. Clark A, Clarke TNS, Gregson B, Hooker PNA, Chambers IR. Variability in pupil size estimation. Emerg Med J. 2006;23:440–1.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  8. Wilson S, Amling JK, Floyd SD, McNair ND. Determining interrater reliability of nurses’ assessment of pupil size. J Neurosci Nurs. 1988;20:189–92.

    Article  PubMed  CAS  Google Scholar 

  9. Van Den Berge JH, Schouten HJA, Boomstra S, Van Drunen Little S, Braakman R. Interobserver agreement in assessment of ocular signs in coma. J Neurol Neurosurg Psychiatry. 1979;42:1163–8.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Litvan I, Saposnik G, Maurino J, Gonzalez L, Saizar R, Sica REP, Bartko JJ. Pupillary diameter assessment: need for a graded scale. Neurology. 2000;54:530.

    Article  PubMed  CAS  Google Scholar 

  11. Larson MD, Muhiudeen I. Pupillometric analysis of the ‘Absent Light Reflex’. Arch Neurol. 1995;52:369–72.

    Article  PubMed  CAS  Google Scholar 

  12. Meeker M, Du R, Bacchetti P, Privitera CM, Larson MD, Holland MC, Manley G. Pupil examination: validity and clinical utility of an automated pupillometer. J Neurosci Nurs. 2005;37(1):34–40.

    Article  PubMed  Google Scholar 

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Conflict of interest

Christopher Kramer, Sara Hocker, Alejandro Rabinstein, and Eelco Wijdicks declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Christopher L. Kramer.

Additional information

All aspects of this study were conducted at the Mayo Clinic Rochester, MN without any financial support.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Video: Pupillary reactivity assessment using the pupillometer and with manual testing. No reactivity is noted with pupillometer testing, however, slow reactivity was seen with a sustained light stimulus upon manual testing. Video specifications: Author: Christopher Kramer, M.D. Videographer: Elaine Flom, Sally Podein. Length: 23 s. Size: 43.3 MB (MP4 44364 kb)

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Kramer, C.L., Rabinstein, A.A., Wijdicks, E.F.M. et al. Neurologist Versus Machine: Is the Pupillometer Better than the Naked Eye in Detecting Pupillary Reactivity. Neurocrit Care 21, 309–311 (2014). https://doi.org/10.1007/s12028-014-9988-5

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  • DOI: https://doi.org/10.1007/s12028-014-9988-5

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