Skip to main content

Advertisement

SpringerLink
Log in

Circulating irisin levels are not correlated with BMI, age, and other biological parameters in obese and diabetic patients

  • Research Letter
  • Published:
Endocrine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. M.A. Febbraio, B.K. Pedersen, Contraction-induced myokine production and release: is skeletal muscle an endocrine organ? Exerc. Sport Sci. Rev. 33(3), 114–119 (2005)

    Article  PubMed  Google Scholar 

  2. F. Sanchis-Gomar, C. Perez-Quilis, Irisinemia: a novel concept to coin in clinical medicine? Ann. Nutr. Metab. 63(1–2), 60–61 (2013)

    Article  CAS  PubMed  Google Scholar 

  3. P. Bostrom, J. Wu, M.P. Jedrychowski, A. Korde, L. Ye, J.C. Lo, K.A. Rasbach, E.A. Bostrom, J.H. Choi, J.Z. Long, S. Kajimura, M.C. Zingaretti, B.F. Vind, H. Tu, S. Cinti, K. Hojlund, S.P. Gygi, B.M. Spiegelman, A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 481(7382), 463–468 (2012)

    Article  PubMed Central  PubMed  Google Scholar 

  4. F. Sanchis-Gomar, The skeletal muscle-metabolism axis in prostate-cancer therapy. N. Engl. J. Med. 367(23), 2257–2258 (2013). doi:10.1056/NEJMc1211955#SA1

    Google Scholar 

  5. F. Sanchis-Gomar, G. Lippi, S. Mayero, C. Perez-Quilis, J.L. Garcia-Gimenez, Irisin: a new potential hormonal target for the treatment of obesity and type 2 diabetes. J. Diabetes 4(3), 196 (2012)

    Article  CAS  PubMed  Google Scholar 

  6. F. Sanchis-Gomar, R. Alis, H. Pareja-Galeano, M. Romagnoli, C. Perez-Quilis, Inconsistency in circulating Irisin levels: what is really happening? Horm. Metab. Res. 46, 1–6 (2014)

    Google Scholar 

  7. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 37(Suppl 1), S81–S90 (2014)

    Google Scholar 

  8. J.Y. Huh, G. Panagiotou, V. Mougios, M. Brinkoetter, M.T. Vamvini, B.E. Schneider, C.S. Mantzoros, FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism 61(12), 1725–1738 (2012)

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  9. Y.K. Choi, M.K. Kim, K.H. Bae, H.A. Seo, J.Y. Jeong, W.K. Lee, J.G. Kim, I.K. Lee, K.G. Park, Serum irisin levels in new-onset type 2 diabetes. Diabetes Res. Clin. Pract. 100(1), 96–101 (2013)

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

This research was supported thanks to the Grant DEP2012-37494 conceded by the Spanish Ministry of Economy and Competitiveness, and it was also supported by the Grants PI13/1025, PI12/01984 and PI13/0073 from FIS and cofunded by the European Regional Development Fund of the European Union (FEDER) and ACOMP/2013/061 from the Regional Ministry of Education of Valencian Community. M Rocha is a recipient of Miguel Servet contract from FIS (CP10/00360). VM Víctor is a recipient of Regional Ministry of Health of Valencian Community and Carlos III Health Institute contract (CES10/030). H Pareja-Galeano is a recipient of FPU contract from the Ministry of Education, Culture and Sport (AP2009-4755).

Conflicts of interest

The authors state that there are no conflict of interest in the publication of this article.

Author information

Authors and Affiliations

  1. Department of Physiology, Faculty of Medicine, University of Valencia, Av. Blasco Ibañez, 15, 46010, Valencia, Spain

    Fabian Sanchis-Gomar, Helios Pareja-Galeano & Victor M. Victor

  2. Institute of Health Research INCLIVA, Valencia, Spain

    Fabian Sanchis-Gomar, Helios Pareja-Galeano, Victor M. Victor, Milagros Rocha & Antonio Hernández-Mijares

  3. University Research Institute “Dr. Viña Giner”, Molecular and Mitochondrial Medicine, Catholic University of Valencia “San Vicente Mártir”, Valencia, Spain

    Rafael Alis & Marco Romagnoli

  4. Service of Endocrinology, University Hospital Dr. Peset, Valencia, Spain

    Eva Sola, Victor M. Victor, Milagros Rocha & Antonio Hernández-Mijares

  5. Foundation for the Promotion of Healthcare and Biomedical Research in the Valencian Community (FISABIO), Valencia, Spain

    Victor M. Victor, Milagros Rocha & Antonio Hernández-Mijares

  6. Department of Medicine, Faculty of Medicine, University of Valencia, Valencia, Spain

    Antonio Hernández-Mijares

  7. Department of Physical Education and Sports, Catholic University of Valencia “San Vicente Mártir”, Valencia, Spain

    Marco Romagnoli

Authors
  1. Fabian Sanchis-Gomar
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Rafael Alis
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Helios Pareja-Galeano
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Eva Sola
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Victor M. Victor
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Milagros Rocha
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Antonio Hernández-Mijares
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Marco Romagnoli
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Fabian Sanchis-Gomar.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sanchis-Gomar, F., Alis, R., Pareja-Galeano, H. et al. Circulating irisin levels are not correlated with BMI, age, and other biological parameters in obese and diabetic patients. Endocrine 46, 674–677 (2014). https://doi.org/10.1007/s12020-014-0170-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12020-014-0170-9

Keywords

Search

Navigation