Skip to main content

Advertisement

SpringerLink
Log in

The use of a glucose spray device to control progression towards hypoglycaemia

  • Research Letter
  • Published:
Endocrine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. P.E. Cryer, L. Axelrod, A.B. Grossman, S.R. Heller, V.M. Montori, E.R. Seaquist, F.J. Service, Evaluation and management of adult hypoglycemic disorders: an endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 94(3), 709–728 (2009)

    Article  PubMed  CAS  Google Scholar 

  2. American Diabetes Association, Standards of medical care in diabetes—2011. Diabetes Care 34, S11–S61 (2011)

    Article  Google Scholar 

  3. B.M. Frier, Hypoglycaemia, ed. by G.J. Biessels, J.A. Luchsinger JA. Diabetes and the Brain, part 3, Chap 6 (Humana Press, New York, 2010)

  4. A. Flint, A. Raben, J.E. Blundell, A. Astrup, Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int. J. Obes. Relat. Metab. Disord. 24, 38–48 (2000)

    Article  PubMed  CAS  Google Scholar 

  5. R. Chlup, J. Zapletalova, K. Peterson, I. Poljakova, E. Lenhartova, A. Tancred, R. Perera, J. Smital, Impact of buccal glucose spray, liquid sugars and dextrose tablets on the evolution of plasma glucose concentration in healthy persons. Biomed. Pap. Med. Fac. Univ. Palacky Olomouc. Czech Repub. 153(3), 205–209 (2009)

    PubMed  CAS  Google Scholar 

  6. H. Zhang, J. Zhang, J.B. Streisand, Oral mucosal drug delivery: clinical pharmacokinetics and therapeutic applications. Clin. Pharmacokinet. 41(9), 661–680 (2002)

    Article  PubMed  CAS  Google Scholar 

  7. R.R. Gunning, A.J. Garber, Bioactivity of instant glucose. Failure of absorption through oral mucosa. JAMA 240(15), 1611–1612 (1978)

    Article  PubMed  CAS  Google Scholar 

  8. T. Kimura, H. Yamano, A. Tanaka, T. Matsamura, M. Ueda, K. Ogawara, K. Higaki, Transport of d-glucose across cultured stratified cell layer of human mucosal cells. J. Pharm. Pharmacol. 54(2), 213–219 (2002)

    Article  PubMed  CAS  Google Scholar 

  9. Y. Oyama, H. Yamano, A. Ohkuma, K. Ogawara, K. Higaki, T. Kimura, Carrier-mediated transport systems for glucose in mucosal cells of the human oral cavity. J. Pharm. Sci. 88(8), 830–834 (1999)

    Article  PubMed  CAS  Google Scholar 

  10. R. Ganeshalingam, M. O’Connor, Evidence behind the WHO guidelines: hospital care for children: what is the efficacy of sublingual, oral and intravenous glucose in the treatment of hypoglycaemia? J. Trop. Pediatr. 55(5), 287–289 (2009)

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

This study was supported by an educational grant to the University Campus Bio-Medico by Generex Biotechnology Corporation which also provided glucose rapid spray devices this study for the trial. The sponsor had no role in the study design, data collection, data analysis or interpretation.

Author information

Authors and Affiliations

  1. Department of Endocrinology and Diabetes, University Campus Bio-Medico, Via Álvaro del Portillo, 21, 00128, Rome, Italy

    Yeganeh Manon Khazrai, Fabio Cacciapaglia, Andrea Palermo & Paolo Pozzilli

  2. Centre of Diabetes, Bart’s and The London School of Medicine and Dentistry, Queen Mary’s University of London, London, UK

    Paolo Pozzilli

Authors
  1. Yeganeh Manon Khazrai
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Fabio Cacciapaglia
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Andrea Palermo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Paolo Pozzilli
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Andrea Palermo.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Khazrai, Y.M., Cacciapaglia, F., Palermo, A. et al. The use of a glucose spray device to control progression towards hypoglycaemia. Endocrine 42, 442–444 (2012). https://doi.org/10.1007/s12020-012-9620-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12020-012-9620-4

Keywords

Search

Navigation