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Salivary Cortisol in Obstructive Sleep Apnea: The Effect of CPAP

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References

  1. G. Carneiro, S.M. Togeiro, L.F. Hayashi, F.F. Ribeiro-Filho, A.B. Ribeiro, S. Tufik, M.T. Zanella, Effect of continuous positive airway pressure therapy on hypothalamic-pituitary-adrenal axis function and 24-h blood pressure profile in obese men with obstructive sleep apnea syndrome. Am. J. Physiol. Endocrinol. Metab. 295, E380–E384 (2008)

    Article  PubMed  CAS  Google Scholar 

  2. N. Meston, R.J.O. Davies, R. Mullins, C. Jenkinson, J.A. Wass, J.R. Stradling, Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnea. J. Int. Med. 254, 447–454 (2003)

    Article  CAS  Google Scholar 

  3. H. Raff, Utility of salivary cortisol measurements in Cushing’s syndrome and adrenal insufficiency. J. Clin. Endocrinol. Metab. 94, 3647–3655 (2009)

    Article  PubMed  CAS  Google Scholar 

  4. M.W. Johns, A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14, 540–549 (1991)

    PubMed  CAS  Google Scholar 

  5. H. Raff, P. Homar, D.P. Skoner, New enzyme immunoassay for salivary cortisol. Clin. Chem. 49, 203–204 (2003)

    Article  PubMed  CAS  Google Scholar 

  6. D.L. Steward, T.C. Huntley, B.T. Woodson, V. Surdulescu, Palate implants for obstructive sleep apnea: multi-institution, randomized, placebo-controlled study. Otolaryngol. Head Neck Surg. 139, 506–510 (2008)

    Article  PubMed  Google Scholar 

  7. L.M. Tomfohr, S. Ancoli-Israel, J.S. Loredo, J.E. Dimsdale, Effects of continuous positive airway pressure on fatigue and sleepiness in patients with obstructive sleep apnea: data from a randomized controlled trial. Sleep 34, 121–126 (2011)

    PubMed  Google Scholar 

  8. A.N. Vgontzas, S. Pejovic, E. Zoumakis, H.M. Lin, C.M. Bentley, E.O. Bixler, A. Sarrigiannidis, M. Basta, G.P. Chrousos, Hypothalamic-pituitary-adrenal axis activity in obese men with and without sleep apnea: Effects of continuous positive airway pressure therapy. J. Clin. Endocrinol. Metab. 92, 4199–4207 (2007)

    Article  PubMed  CAS  Google Scholar 

  9. A. Schmoller, F. Eberhardt, K. Jauch-Chara, U. Schweiger, P. Zabel, A. Peters, B. Schultes, K.M. Oltmanns, Continuous positive airway pressure therapy decreases evening cortisol concentrations in patients with severe obstructive sleep apnea. Metab. Clin. Exp. 58, 848–853 (2009)

    PubMed  CAS  Google Scholar 

  10. F. Dadoun, P. Darmon, V. Achard, S. Boullu-Ciocca, F. Philip-Joet, M.C. Alessi, M. Rey, M. Grino, A. Dutour, Effect of sleep apnea syndrome on the circadian profile of cortisol in obese men. Am. J. Physiol. Endocrinol. Metab. 293, E466–E474 (2007)

    Article  PubMed  CAS  Google Scholar 

  11. A.N. Vgontzas, E.O. Bixler, H.-M. Lin, P. Prolo, Vela.-Bueno.A. Mastorakos, A. Kales, G.P. Chrousos, Chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis: clinical implications. J. Clin. Endocrinol. Metab. 86, 2787–2794 (2001)

    Article  Google Scholar 

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Acknowledgments

Supported in part by grants from the ResMed Foundation and 1UL1RR031973 from the Clinical and Translational Science Award (CTSA) program of the National Center for Research Resources, National Institutes of Health. Mucinex samples provided by Adams Respiratory Therapeutics, Dallas, TX. The authors thank Peter Homar for performing the hormone assays and Lauren Markowski with assistance in preparation of the manuscript.

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Correspondence to Hershel Raff.

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Registered on clinicaltrials.gov−NCT01196117.

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Raff, H., Ettema, S.L., Eastwood, D.C. et al. Salivary Cortisol in Obstructive Sleep Apnea: The Effect of CPAP. Endocrine 40, 137–139 (2011). https://doi.org/10.1007/s12020-011-9474-1

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  • DOI: https://doi.org/10.1007/s12020-011-9474-1

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