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The diagnosis and management of anaphylaxis

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Comprehensive Therapy

Abstract

Anaphylaxis is amongst the most frightening reactions that any physician will face. What often separates life and death is the acute management, including the proper use of epinephrine. In this review, the differential diagnosis and management plan are outlined.

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References

  1. Brown AF, McKinnon D, Chu K. Emergency department anaphylaxis: A review of 142 patients in a single year. J Allergy Clin Immunol. 2001;108:861–6.

    Article  PubMed  CAS  Google Scholar 

  2. Yocum MW, Butterfield JH, Klein JS, Volcheck GW, Schroeder DR, Silverstein MD. Epidemiology of anaphylaxis in Olmsted County: A population-based study. J Allergy Clin Immunol. 1999;104:452–6.

    Article  PubMed  CAS  Google Scholar 

  3. The diagnosis and management of anaphylaxis. Joint Task Force on Practice Parameters, American Academy of Allergy, Asthma and Immunology, American College of Allergy, Asthma and Immunology, and the Joint Council of Allergy, Asthma and Immunology. J Allergy Clin Immunol. 1998;101: S465–528.

    Google Scholar 

  4. Kemp SF, Lockey RF. Anaphylaxis: a review of causes and mechanisms. J Allergy Clin Immunol. 2002;110:341–8.

    Article  PubMed  CAS  Google Scholar 

  5. Project Team of the Resuscitation Council (UK). Consensus guidelines: emergency medical treatment of anaphylactic reactions. Resuscitation. 1999;41:93–9.

    Google Scholar 

  6. Anderson JA. The allergist responsibilities in anaphylaxis: documentation, prevention, and patient and public education. Immunol Allergy Clin N Am. 2001;21:827–831.

    Google Scholar 

  7. Kemp SF. Current concepts in pathophysiology, diagnosis, and management of anaphylaxis. Immunol Allergy Clin N Am. 2001;21:611–34.

    Google Scholar 

  8. Ellis AK, Day JH. Diagnosis and management of anaphylaxis. CMAJ. 2003;169:307–12.

    PubMed  Google Scholar 

  9. Sporik R, Hill DJ, Hosking CS. Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children. Clin Exp Allergy. 2000;30: 1540–6.

    Article  PubMed  CAS  Google Scholar 

  10. Yunginger JW, Ahlstedt S, Eggleston PA, et al. Quantitative IgE antibody assays in allergic diseases. J Allergy Clin Immunol. 2000;105:1077–84.

    Article  PubMed  CAS  Google Scholar 

  11. Clark AT, Ewan PW. Interpretation of tests for nut allergy in one thousand patients, in relation to allergy or tolerance. Clin Exp Allergy. 2003;33:1041–5.

    Article  PubMed  CAS  Google Scholar 

  12. Guidelines to minimize the risk from systemic reactions caused by immunotherapy with allergenic extracts. AAAI Board of Directors. American Academy of Allergy and Immunology. J Allergy Clin Immunol. 1994;93:811–2.

  13. Shimamoto SR, Bock SA. Update on the clinical features of food-induced anaphylaxis. Curr Opin Allergy Clin Immunol. 2002;2:211–6.

    Article  PubMed  Google Scholar 

  14. Horan RF, DuBuske LM, Sheffer AL. Exercise-induced anaphylaxis? Immunol Allergy Clin North Am. 2001;21:559–69.

    Article  Google Scholar 

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The authors have stated that they do not have a significant financial interest or other relationship with any product manufacturer or provider of services discussed in this article. The authors also do not discuss the use of off-label products, which includes unlabeled, unapproved. or investigative products or devices.

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Borchers, A.T., Naguwa, S.M., Keen, C.L. et al. The diagnosis and management of anaphylaxis. Compr Ther 30, 111–120 (2004). https://doi.org/10.1007/s12019-004-0006-2

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  • DOI: https://doi.org/10.1007/s12019-004-0006-2

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