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Hormone replacement therapy for menopausal women

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Comprehensive Therapy

Abstract

Hormone replacement therapy is postmenopausal women offers important benefits for preventing chronic disabling diseases, including prevention of osteoporosis and decreased risk of colon cancer. Although such therapy also carries various possible increased risks, most women will benefit from this therapy.

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References

  1. Kuiper GGJM, Carlson B, Grandian K, et al. Comparison of ligand binding specificity and transcript distribution of estrogen receptors α and β. Endocrinology. 1977;138:863–870.

    Article  Google Scholar 

  2. Cooper J, Thompson JM, Poller L. Effects of natural oestrogen replacement therapy on menopausal symptoms and blood clotting. BMJ. 1975;4:139–143.

    Article  Google Scholar 

  3. Kronenberg G. Hot flushes. In: Lobo RA, ed. Treatment of the Postmenopausal Woman. New York: Raven Press Publishers; 1994:97–117.

    Google Scholar 

  4. Cardozo L, Bachman G, McClish D, et al. Meta-analysis of estrogen therapy in management of urogenital atrophy in postmenopausal women: second report on the Hormone and Urogenital Therapy Committee. Obstet Gynecol.. 1998;92:722–727.

    Article  PubMed  CAS  Google Scholar 

  5. Writing Group for the PEPI trial. Effects of hormone therapy on bone mineral density. JAMA. 1996;276:1389–1396.

    Article  Google Scholar 

  6. Gallagher JC. Estrogen: prevention and treatment of osteoporosis. In: Marcus et al, eds. Osteoporosis. San Diego, Calif: Academic Press; 1995:1191–1208.

    Google Scholar 

  7. Writing Group for the PEPI trial. Effect of estrogen or estrogen/progestin regimens on breast change: risk factors in postmenopausal women. JAMA. 1995;273:199–208.

    Article  Google Scholar 

  8. Daly E, Vessey MP, Hawkins MM, et al. Risk of venous thromboembolism in users of hormone replacement therapy. Lancet. 1996;348:977–980.

    Article  PubMed  CAS  Google Scholar 

  9. Devar M, Barrett-Conner E, Renvall M, et al. Estrogen replacement therapy and the risk of venous thrombosis. Am J Med. 1992;92:275–282.

    Article  Google Scholar 

  10. Grady D. Postmenopausal hormone therapy increases risk of deep vein thrombosis and pulmonary embolism. Am J Med. 1998;105:41–43.

    Article  PubMed  CAS  Google Scholar 

  11. Yaffe K, Sawaya G, Lieberburg I. et al. Estrogen therapy in postmenopausal women: effect on cognitive function and dementia. JAMA. 1998;279:688–695.

    Article  PubMed  CAS  Google Scholar 

  12. Nanda K, Bastia LA, Hasselblad V, et al. Hormone replacement therapy and the risk of colorectal cancer: a meta-analysis. Obstet Gynecol. 1999;93:880–888.

    Article  PubMed  CAS  Google Scholar 

  13. Grodstein F, Newcomb PA, Stampfer MJ. Postmenopausal hormone therapy and the risk of colorectal cancer: a review and meta-analysis. Am J Med. 1999;106;574–582.

    Article  PubMed  CAS  Google Scholar 

  14. Birkenfeld L, Yamini M, Kase NH, et al. Menopause-related oral alveolar bone resorption: a review of relatively unexplored consequence of estrogen deficiency. Menopause. 1999;6:129–133.

    Article  PubMed  CAS  Google Scholar 

  15. Pearson, I, et al. Cancer incidence and mortality in women receiving estrogen and estrogen-progestin replacement therapy: long-term follow-up of a Swedish cohort. Int J Cancer. 1996;67:327–332.

    Article  Google Scholar 

  16. Collaborative Group on Hormone Factors in Breast Cancer. Breast cancer and hormone replacement therapy: collaborative re-analysis of data from 51 epidemiologic studies of 51,705 women with breast cancer and 108,411 women without breast cancer. Lancet. 1997;350:1047–1059.

    Article  Google Scholar 

  17. Gapstur S, Morrow M, Sellers TA. Hormone replacement therapy and risk of breast cancer with a favorable histology: result of Iowa Women's Health Study. JAMA. 1999;281:2091–2097.

    Article  PubMed  CAS  Google Scholar 

  18. Spencer CP, Morris EP, Rymer JM. Selective estrogen receptor modulators: women's panacea for the next millennium. Am J Obstet Gynecol. 1999;180:763–770.

    Article  PubMed  CAS  Google Scholar 

  19. Fisher B, Constantino JP, Wickerham L, et al. Tamoxifen for the prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. Nat Cancer Inst. 1998;90:1371–1388.

    Article  CAS  Google Scholar 

  20. Cummings SR, Ecket C, Krueger K, et al. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the More randomized trial. JAMA. 1999;281:2189–2197.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Div. of Reproductive Endocrinology, Wayne State University. Hutzel Hospital, 4707 St. Antoine Blv., 48201, Detroit, MI

    Kamran S. Moghissi MD

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  1. Kamran S. Moghissi MD
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Moghissi, K.S. Hormone replacement therapy for menopausal women. Compr Ther 26, 197–202 (2000). https://doi.org/10.1007/s12019-000-0009-6

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  • DOI: https://doi.org/10.1007/s12019-000-0009-6

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