Abstract
There are four body composition phenotypes widely used to describe older adults: normal, sarcopenic, obese, and sarcopenic obese. In this paper, we will discuss how DXA can be used to quantify body composition and how DXA can identify patients with sarcopenia and sarcopenic obesity.
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Kelly TL, Slovik DM, Neer RM. Calibration and standardization of bone mineral densitometers. J Bone Miner Res. 1989;4:663–9.
Laskey M, Phil D. Dual-energy X-ray absorptiometry and body composition. Nutrition. 1996;12:45–51.
Kelly TL, Berger N, Richardson TL. DXA body composition: theory and practice. Appl Radiat Isot. 1998;49:511–3.
Pietrobelli A, Formica C, Wang Z, Heymsfield SB. Dual-energy X-ray absorptiometry body composition model: review of physical concepts. Am J Physiol. 1996;271:E941–51.
Blake GM, Fogelman I. Technical principles of dual energy X-ray absorptiometry. Semin Nucl Med. 1997;27:210–28.
Sheng HP, Huggins RA. A review of body composition studies with emphasis on total body water and fat. Am J Clin Nutr. 1979;32:630–47.
Powers C, Fan B, Borrud L, Shepherd J. Evaluation of whole body and subregional DXA precision. J Clin Densitom. 2011;14:166.
Bischoff-Ferrari H, Orav J, Kanis J, Rizzoli R, Schlögl M, Staehelin H, Willett W, Dawson-Hughes B. Comparative performance of current definitions of sarcopenia against the prospective incidence of falls among community-dwelling seniors age 65 and older. Population. 2015;9:14.
Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, Garry PJ, Lindeman RD. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998;147:755–63.
Delmonico MJ, Harris TB, Lee JS, Visser M, Nevitt M, Kritchevsky SB, Tylavsky FA, Newman AB. Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women. J Am Geriatr Soc. 2007;55:769–74.
Delmonico MJ, Harris TB, Visser M, Park SW, Conroy MB, Velasquez-Mieyer P, Boudreau R, Manini TM, Nevitt M, Newman AB. Longitudinal study of muscle strength, quality, and adipose tissue infiltration. Am J Clin Nutr. 2009;90:1579–85.
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people. Age Age. 2010;39:412–23.
Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, van Kan GA, Andrieu S, Bauer J, Breuille D. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011;12:249–56.
Muscaritoli M, Anker S, Argiles J, Aversa Z, Bauer J, Biolo G, Boirie Y, Bosaeus I, Cederholm T, Costelli P. Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG)“cachexia-anorexia in chronic wasting diseases” and “nutrition in geriatrics”. Clin Nutr. 2010;29:154–9.
Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR, Harris TB, Ferrucci L, Guralnik JM, Fragala MS, Kenny AM. The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol Ser A Biol Sci Med Sci. 2014;69:547–58.
Prado CM, Siervo M, Mire E, Heymsfield SB, Stephan BC, Broyles S, Smith SR, Wells JC, Katzmarzyk PT. A population-based approach to define body-composition phenotypes. Am J Clin Nutr. 2014;99:1369–77.
Genant HK, Grampp S, Gluer CC, Faulkner KG, Jergas M, Engelke K, Hagiwara S, Van Kuijk C. Universal standardization for dual x-ray absorptiometry: patient and phantom cross-calibration results. J Bone Miner Res. 1994;9:1503–14.
Lu Y, Fuerst T, Hui S, Genant HK. Standardization of bone mineral density at femoral neck, trochanter and Ward’s triangle. Osteoporos Int. 2001;12:438–44.
Shepherd JA, Cheng XG, Lu Y, Njeh C, Toschke J, Engelke K, Grigorian M, Genant HK. Universal standardization of forearm bone densitometry. J Bone Miner Res. 2002;17:734–45.
Shepherd JA, Fan B, Lu Y, Wu XP, Wacker WK, Ergun DL, Levine MA. A multinational study to develop universal standardization of whole-body bone density and composition using GE Healthcare Lunar and Hologic DXA systems. J Bone Miner Res. 2012;27:2208–16.
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John Shepherd has received research grants from Amgen, Hologic, GE Healthcare, Merck.
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Shepherd, J. Evaluation of Sarcopenia by DXA. Clinic Rev Bone Miner Metab 14, 45–49 (2016). https://doi.org/10.1007/s12018-016-9206-4
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DOI: https://doi.org/10.1007/s12018-016-9206-4