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Less Travelled Roads in Clinical Immunology and Allergy: Drug Reactions and the Environmental Influence

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Abstract

Allergy and clinical immunology are examples of areas of knowledge in which working hypotheses are dominant over mechanistic understanding. As such, sometimes scientific efforts follow major streams and overlook some epidemiologically prevalent conditions that thus become underestimated by the research community. For this reason, we welcome the present issue of Clinical Reviews in Allergy and Immunology that is dedicated to uncommon themes in clinical immunology and allergy. First, comprehensive discussions are provided for allergy phenomena of large potential impact in clinical practice such as reactions to cephalosporins or aspirin-induced asthma and in everyday life such as allergies to food additives or legumes. Further, the issue addresses other uncommon themes such as urticaria and angioedema, cercarial dermatitis, or late-onset inflammation to soft tissue fillers. Last, there will be discussion on transversal issues such as olfactory defects in autoimmunity, interleukin 1 beta pathway, and the search for new serological markers in chronic inflammation. As a result, we are convinced that this issue will be of help to clinicians involved in internal medicine as well as to allergists and clinical immunologists. More importantly, we are convinced that these discussions will be of interest also to basic scientists for the numerous translational implications.

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Authors and Affiliations

  1. University of Milan, Milan, Italy

    Carlo Selmi & Pier Luigi Meroni

  2. Division of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, via A. Manzoni 56, 20089, Rozzano, Milan, Italy

    Carlo Selmi & Chiara Crotti

  3. Research Laboratory of Immuno-Rheumatology, Istituto Auxologico Italiano, Milan, Italy

    Pier Luigi Meroni

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Correspondence to Carlo Selmi.

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Selmi, C., Crotti, C. & Meroni, P.L. Less Travelled Roads in Clinical Immunology and Allergy: Drug Reactions and the Environmental Influence. Clinic Rev Allerg Immunol 45, 1–5 (2013). https://doi.org/10.1007/s12016-013-8381-z

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