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Promising New Sources for Pluripotent Stem Cells

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Abstract

Recent findings have placed stem cell research at the forefront of biomedical sciences. Basic research on embryonic stem cells (ESCs) has contributed to our knowledge about the developmental potential and plasticity of stem cells. Furthermore, it has raised hope to use these cells as potential source for regenerative medicine and tissue replacement after injury or disease. Unfortunately, ESCs can also form tumors and they are ethically controversial because they originate from human embryos. This review summarizes findings and therapeutic applications of ESCs and their alternatives: adult stem cells and iPS cells.

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Acknowledgments

This work was supported by the Novus Sanguis research consortium (449-MC1-2006B). We are grateful to Nico Forraz for his support and scientific guidance as well as Aaron Gardner for providing the cord figure.

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Authors and Affiliations

  1. Ludwig Boltzmann Institute for Cancer Research, Währingerstrasse 13A, Vienna, Austria

    Christian Leeb, Richard Moriggl & Lukas Kenner

  2. Cell Therapy Research Institute CTI-LYON, Parc Technologique de Lyon-Saint Priest, 97 Allee Alexandre Borodine, Saint Priest, 69800, France

    Marcin Jurga & Colin McGuckin

  3. Institute of Clinical Pathology, Währinger Gürtel 18-20, Vienna, Austria

    Lukas Kenner

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  1. Christian Leeb
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  2. Marcin Jurga
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  3. Colin McGuckin
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Correspondence to Lukas Kenner.

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Leeb, C., Jurga, M., McGuckin, C. et al. Promising New Sources for Pluripotent Stem Cells. Stem Cell Rev and Rep 6, 15–26 (2010). https://doi.org/10.1007/s12015-009-9102-0

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