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Relationship Between Myocardial Bridging and Coronary Arteriosclerosis

  • Translational Biomedical Research
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Abstract

The objective of the study was to explore the prevalence and characteristics of myocardial bridging in patients who underwent coronary angiography and to also evaluate the correlation between bridged coronary segments and atherosclerosis. For this purpose, clinical materials of 1,500 patients who had received coronary angiography were retrospectively analyzed. The location and length of the myocardial bridge were recorded as well as the extent and location of coronary artery stenosis was described. Segments proximal and distal to the bridging were evaluated for coronary arteriosclerosis as were the remaining coronary segments. We found that myocardial bridging was present in 179 (11.9 %) patients. Bridges were frequently (84.9 %) localized in the mid-distal segment of the left anterior descending (LAD) artery. Myocardial bridging was not considered a significant risk factor for coronary atherosclerosis (odds ratio 0.58) compared with traditional cardiovascular risk factors. The incidence of coronary arteriosclerosis in the distal segments was significantly less affected than the proximal segments (P < 0.01). It was, therefore, concluded that myocardial bridging frequently localized in the mid-distal segment of the LAD artery. The presence of myocardial bridging promotes proximal atherosclerosis but it is not an additional risk factor for coronary atherosclerosis.

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Acknowledgments

The authors wish to thank the collaborators for their hard work in recruiting and following-up patients for clinical trials, and Jinggen Ouyang for his valuable help regarding the manuscript preparation.

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Authors and Affiliations

  1. Department of Cardiology, Aviation General Hospital, An Ding Men Wai Bei Yuan Road 3, Beijing, 100012, China

    Jian Ling Sun & Chong Yu Wang

  2. The Second Department of Spine Surgery, The Sixth Affiliated Hospital of Xinjiang Medical University, Wu Lu Mu Qi Wu Xing Nan Road 39, Wulumuqi, 830002, China

    Wei Min Huang

  3. Electrophysiology Group, Department of Cardiology, People’s Hospital, Peking University, Beijing, China

    Wei Min Huang & Ji Hong Guo

  4. Department of Geriatric Cardiology, The Chinese People’s Liberation Army General Hospital, Beijing, China

    Xiao Ying Li

  5. Department of Cardiology, Beijing Jian Gong Hospital, Beijing, China

    Xian Lin Ma

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  1. Jian Ling Sun
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  2. Wei Min Huang
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  3. Ji Hong Guo
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  4. Xiao Ying Li
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  5. Xian Lin Ma
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  6. Chong Yu Wang
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Correspondence to Jian Ling Sun or Wei Min Huang.

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Sun, J.L., Huang, W.M., Guo, J.H. et al. Relationship Between Myocardial Bridging and Coronary Arteriosclerosis. Cell Biochem Biophys 65, 485–489 (2013). https://doi.org/10.1007/s12013-012-9438-y

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  • DOI: https://doi.org/10.1007/s12013-012-9438-y

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