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Iodine-125 Seed Implantation in the Treatment of Sacrococcygeal Chordoma: A Case Report

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Abstract

The objective of this was to summarize the efficacy and safety of iodine-125 seed implantation in the treatment of sacrococcygeal chordoma. CT-guided implantation of radioactive iodine-125 seed was applied in treating a patient with sacrococcygeal chordoma. The incidence of complications was recorded and the results were evaluated and analyzed, to compare the postoperative complications and recurrence rate of sacrococcygeal chordoma. The patient was followed up to 15 months after operation. The minimum peripheral dose was 180 Gy, and 8 months after the implantation, the tumor mass was reduced significantly. There was no serious complications detected during the follow-up period. Radioactive iodine-125 seed implantation can improve the target volume dose, with the high doses of radioactive iodine-125 seed, the tumor, which was refractory and insensitive to chemotherapy and radiotherapy, can be effectively controlled and complications are less than surgical treatment. However, the long-term efficacy of this treatment needs further follow-up.

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Authors and Affiliations

  1. Cancer Center, Institute of Surgical Research, Daping Hospital, Third Military Medical University, Chongqing, 400042, China

    Rong-hui Ni, Ge Wang, Zhi-min Zhang & Jun-gang Ma

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  1. Rong-hui Ni
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  2. Ge Wang
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  3. Zhi-min Zhang
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  4. Jun-gang Ma
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Correspondence to Ge Wang.

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Ni, Rh., Wang, G., Zhang, Zm. et al. Iodine-125 Seed Implantation in the Treatment of Sacrococcygeal Chordoma: A Case Report. Cell Biochem Biophys 64, 107–113 (2012). https://doi.org/10.1007/s12013-012-9378-6

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  • DOI: https://doi.org/10.1007/s12013-012-9378-6

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