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Studies on Edema Pathema in Hequ Horse in the Qinghai-Tibet Plateau

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Abstract

As a consequence of contracted and fenced grassland, the incidence of edema pathema in the Hequ horse is rising. The main pathological symptoms are edema, emaciation, anemia, heterophilia, inappetence, and dyskinesia. To study the cause of edema disease in Hequ horse, the Hequ horse farm with a high incidence was chosen as the experimental pasture, and the Azi husbandry experimental station without edema disorder was the control pasture. The research methods in this paper are included: (1) The mineral contents in soil, forage, blood, and liver were analyzed. (2) Routine parameters and biochemical values in blood were also measured. (3) Conduct a prevention trial and a treatment experiment. The results showed that Se contents in soil and forage was much significantly lower than that in the control group (P < 0.01), and there was no significant difference in other elements. Se contents in blood and liver in affected animals were very significantly lower than those of the control group (P < 0.01). Hb, HCT, MCV, and MCH were greatly significantly lower than those in the control group (P < 0.01). Activities of GSH-Px in blood were very significantly lower than those of the control group (P < 0.01). Before the onset season of the disorder in the affected area, Na2SeO3 was used to conduct a prevention trial on 1576 Hequ horses. A dose of 0.03 mg Na2SeO3 was given orally per kilogram of body weight, once every 15 days and twice continuously. There was no edema illness that year. In the treatment experiment, 235 horses were administered Na2SeO3 orally at 0.04 mg per kilogram of body weight, once every 3 days for 4 consecutive times, and 198 horses were cured, with a cure rate of 84.26%. Therefore, it is possible that Hequ horse edema pathema is caused by Se deficiency in soil and forage.

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Funding

This work was supported by the national natural science foundation of China (41671041) and the project of national key research and development program of China in 13th five-year plan (2016YFC0502601).

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Authors and Affiliations

  1. School of Materials and Architectural Engineering, Guizhou Normal University, Guiyang, 550025, China

    Kui Zhao

  2. School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China

    Kui Zhao & Xiaoyun Shen

  3. State Engineering Technology Institute for Karst Desertification Control, Guizhou Normal University, Guiyang, 550025, China

    Yongkuan Chi & Xiaoyun Shen

  4. World Bank Poverty Alleviation Project Office in Guizhou, Guiyang, 550004, Southwest China, China

    Xiaoyun Shen

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  1. Kui Zhao
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  2. Yongkuan Chi
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Correspondence to Xiaoyun Shen.

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The authors declare that they have no conflict of interest.

Ethical Approval

The Hequ horse used in these studies were cared as per outlined in the Guide for the Care and Use of Animals in Agricultural Research and Teaching Consortium (Federation of Animals Science Societies. 2010). Sample collections in animals were approved by the Southwest University of Science and Technology in China, Institutional Animal Care and Use Committee (Project A00593).

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Zhao, K., Chi, Y. & Shen, X. Studies on Edema Pathema in Hequ Horse in the Qinghai-Tibet Plateau. Biol Trace Elem Res 198, 142–148 (2020). https://doi.org/10.1007/s12011-020-02043-9

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  • DOI: https://doi.org/10.1007/s12011-020-02043-9

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