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Reversible Hypomagnesaemia-Induced Subacute Cerebellar Syndrome

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Abstract

Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe a case of severe hypomagnesaemia associated with intermittent downbeat nystagmus, cerebellar ataxia, generalised convulsions and a supraventricular tachycardia. On MRI imaging, a transient lesion of the cerebellar nodulus was observed, which has not, to our knowledge, been previously described in isolated hypomagnesaemia.

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Correspondence to Saam Sedehizadeh.

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Sedehizadeh, S., Keogh, M. & Wills, A.J. Reversible Hypomagnesaemia-Induced Subacute Cerebellar Syndrome. Biol Trace Elem Res 142, 127–129 (2011). https://doi.org/10.1007/s12011-010-8757-3

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