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Significance of Trace Element Profile of Blood of Persons with Multiple Caries versus Sound Teeth

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Abstract

In order to determine any possible relation between chemical composition of a person’s blood to formation of dental caries, whole blood was analyzed for 35 inorganic elements (Si, Al, Fe, Ca, Mg, K, Mn, Ti, P, Li, Be, B, V, Cr, Co, Ni, Cu, Zn, As, Sr, Y, Nb, Mo, Ag, Cd, Sn, Sb, Ba, La, Ce, W, Pb, Bi, Zr, and F) in the 15 people having sound teeth as well as an equal number of those having multiple caries. The results showed the absence of 13 elements (Si, Al, Mn, Ti, Be, Co, As, Y, Cd, Ba, La, Ce, and Zr) in the blood of both groups. Of the remaining 22 elements, the results of only seven elements (Fe, P, B, V, Sr, Sn, and F) were significantly different between the two groups. The most remarkable finding of this study was significantly decreased amount of phosphorus, strontium, and fluorine and perhaps increased boron in the blood of persons with caries.

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References

  1. Curzon ME, Losee FL (1978) Dental caries and trace element composition of whole human enamel: Western United States. J Am Dent Assoc 96:819–822

    CAS  PubMed  Google Scholar 

  2. Verbic V, Stuper J (1980) Dental caries and the concentration of aluminium and strontium in enamel. Caries Res 14:141–147

    Article  Google Scholar 

  3. Murray JJ, Rugg-Gunn AJ, Jenkins GN (1999) Fluorides in caries prevention, 3rd edn. Butterworth-Heinemann, Oxford, pp 262–294

    Google Scholar 

  4. Riyat M, Sharma DC (2009a) Analysis of 35 inorganic elements in teeth in relation to caries formation. Biol Trace Elem Res 129:126–129

    Article  CAS  PubMed  Google Scholar 

  5. Thiers RE (1957) Contamination in trace element analysis and its control. In: Glick D (ed) Methods of biochemical analysis, vol. V. Interscience, New York, pp 273–335

    Chapter  Google Scholar 

  6. Gierat-Kucharzewska B, Karasinski A (2006) Influence of chosen elements on the dynamics of cariogenic process. Biol Trace Elem Res 111:53–62

    Article  CAS  PubMed  Google Scholar 

  7. WHO (1996) Trace elements in human nutrition and health. World Health Organization, Geneva, pp 175–179

    Google Scholar 

  8. Nielsen FH (1991) Nutritional requirements for boron, silicon, vanadium, nickel and arsenic: current knowledge and speculation. FASEB J 5:2661–2667

    CAS  PubMed  Google Scholar 

  9. WHO (1993) Boron. In: Guidelines for drinking water-quality—vol. 1: recommendations. World Health Organization, Geneva, pp 43–44

  10. Nielsen FH, Schuler TR (1992) Studies of the interaction between boron and calcium and its modification by magnesium and potassium in rats: effects on growth, blood variables and bone mineral composition. Biol Trace Elem Res 35:225–237

    Article  CAS  PubMed  Google Scholar 

  11. Gopalan C, Rama Sastri BV, Balasubramanian SC (1993) Nutritive value of Indian foods. National Institute of Nutrition, Hyderabad, pp 47–58

    Google Scholar 

  12. Moe SM (2008) Disorders involving calcium, phosphorus and magnesium. Prim Care 35:215–230

    PubMed  Google Scholar 

  13. Schroeder HA, Tipton IH, Nason AP (1972) Trace metals in man: strontium and barium. J Chron Dis 25:491–517

    Article  CAS  PubMed  Google Scholar 

  14. Block JH, Roche EB, Soine TO, Wilson CO (1986) Inorganic medicinal and pharmaceutical chemistry. Lea & Febiger, Philadelphia, p 56

    Google Scholar 

  15. Riyat M, Sharma DC (2009b) An experimental study on the effect of strontium pre-treatment on calcium release from carious and non-carious teeth. Biol Trace Elem Res doi:10.1007/s12011-009-8435-5

  16. Anonymous (1983) Strontium and dental caries. Nutr Rev 41:342–344

    Google Scholar 

  17. Curzon MEJ, Losee FL (1977) Strontium content of enamel and caries. Caries Res 11:321–326

    Article  CAS  PubMed  Google Scholar 

  18. Anonymous (2005) Strontium: the first bone builder. Adv Orthomol Res 3:1–11

    Google Scholar 

  19. Pi M, Quarles LD (2004) A novel cation-sensing mechanism in osteoblasts is a molecular target for strontium. J Bone Miner Res 19:862–869

    Article  CAS  PubMed  Google Scholar 

  20. Guyton AC, Hall JE (2006) Textbook of medical physiology, 11th edn. Saunders, Philadelphia, pp 981–983 and 992–994

  21. Sharma DC, Riyat M (2008) Biochemistry for dental students. B.I. Publications, New Delhi, pp 3–9 and 106–108

  22. Johnson AR, Armstrong WD, Singer L (1966) Strontium incorporation into dental enamel. Science 153:1396–1397

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

The authors wish to thank SGT Dental College management for the research grant and Geological Survey of India, Faridabad, and R & D Center, Sunbeam Auto Limited, Gurgaon, for help in the analysis of samples.

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Authors and Affiliations

  1. Department of Biochemistry, S. G. T. Dental College, Hospital & Research Institute, Budhera, Gurgaon, 123505, Haryana, India

    Manminder Riyat & Dinesh Chandra Sharma

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  1. Manminder Riyat
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  2. Dinesh Chandra Sharma
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Correspondence to Dinesh Chandra Sharma.

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Riyat, M., Sharma, D.C. Significance of Trace Element Profile of Blood of Persons with Multiple Caries versus Sound Teeth. Biol Trace Elem Res 134, 174–179 (2010). https://doi.org/10.1007/s12011-009-8470-2

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  • DOI: https://doi.org/10.1007/s12011-009-8470-2

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