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Simultaneous Determination of Cd, Pb, Cu, Zn, and Se in Human Blood of Jordanian Smokers by ICP-OES

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An Erratum to this article was published on 20 October 2009

Abstract

A total of 73 blood samples (56 from smokers and 17 from nonsmokers) were collected to determine the concentrations of selected heavy metal in the whole blood of smokers and nonsmokers living in and around the city of Amman, Jordan. Analysis of heavy metals in the whole blood samples of various groups took in consideration the number of cigarettes smoked per day. The analysis of blood samples was carried out using inductively coupled plasma optical emission spectrometry. This study aimed to evaluate the blood metal levels in smokers and nonsmokers and to assess the influence of smoking cigarettes on blood metal levels. The results were compared with those from a control group. The results indicated that the average concentrations of cadmium (Cd), lead (Pb), copper (Cu), zinc (Zn), and selenium (Se) were 0.0313, 0.344, 2.328, 3.214, and 0.332 mg/L, respectively. Statistical analysis of results indicated that these average concentrations were significantly higher compared with the average concentrations in nonsmokers (P < 0.05). Moreover, the correlations between blood metal and other blood metal levels in smokers, the correlations between blood metal and other blood metal levels in nonsmokers, and the correlations between blood metal concentration in smokers and its concentration in nonsmokers were calculated. The standard reference material (blood serum National Institute of Standards and Technology 1598) and the quality control were used to validate the reliability of the method used for the estimation of heavy metals in blood samples. Results revealed that there was an agreement between the certified values and the measured values.

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Acknowledgment

The authors would like to thank Jordan University of Science and Technology for financial assistance, and for the Committee of Research on the Human, in particular Professor Dr. Hukum Al-Hadeedi, and we express our appreciation to the department of chemistry at Yarmouk University for cooperation to analyze the samples using ICP-OES. Many thanks are due to Al-Qodus Medical Laboratory, Amman, for cooperation and assistance during the collection of blood samples.

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Authors and Affiliations

  1. Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan

    Adnan Massadeh

  2. Department of Applied Chemistry, Faculty of Science, Jordan University of Science and Technology, Irbid, Jordan

    Ahmed Gharibeh & Khaled Omari

  3. Department of Chemistry, Faculty of Science, Yarmouk University, Irbid, Jordan

    Idrees Al-Momani & Ahmed Alomari

  4. Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan

    Hiatham Tumah

  5. Department of Pediatrics, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan

    Wail Hayajneh

Authors
  1. Adnan Massadeh
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  2. Ahmed Gharibeh
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  3. Khaled Omari
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  4. Idrees Al-Momani
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  5. Ahmed Alomari
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  6. Hiatham Tumah
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  7. Wail Hayajneh
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Corresponding author

Correspondence to Adnan Massadeh.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1007/s12011-009-8543-2

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Massadeh, A., Gharibeh, A., Omari, K. et al. Simultaneous Determination of Cd, Pb, Cu, Zn, and Se in Human Blood of Jordanian Smokers by ICP-OES. Biol Trace Elem Res 133, 1–11 (2010). https://doi.org/10.1007/s12011-009-8405-y

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  • DOI: https://doi.org/10.1007/s12011-009-8405-y

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