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Carbon Nanotubes-Based Label-Free Affinity Sensors for Environmental Monitoring

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Abstract

Nanostructures, such as nanowires, nanobelts, nanosprings, and nanotubes, are receiving growing interest as transducer elements of bio/chemical sensors as they provide high sensitivity, multiplexing, small size, and portability. Single-walled carbon nanotubes (SWNTs) are one such class of nanostructure materials that exhibit superior sensing behavior due to its large-surface carbon atoms that are highly responsive to surface adsorption events. Further, their compatibility with modern microfabrication technologies and facile functionalization with molecular recognition elements make them promising candidates for bio/chemical sensors applications. Here, we review recent results on nanosensors based on SWNTs modified with biological receptors such as aptamers, antibodies, and binding proteins, to develop highly sensitive, selective, rapid, and cost-effective label-free chemiresistor/field-effect transistor nanobiosensors for applications in environmental monitoring.

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Authors and Affiliations

  1. Department of Chemical and Environmental Engineering, University of California Riverside, Riverside, CA, 92521, USA

    Tapan Sarkar, Yingning Gao & Ashok Mulchandani

Authors
  1. Tapan Sarkar
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  2. Yingning Gao
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  3. Ashok Mulchandani
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Correspondence to Ashok Mulchandani.

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Sarkar, T., Gao, Y. & Mulchandani, A. Carbon Nanotubes-Based Label-Free Affinity Sensors for Environmental Monitoring. Appl Biochem Biotechnol 170, 1011–1025 (2013). https://doi.org/10.1007/s12010-013-0233-z

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  • DOI: https://doi.org/10.1007/s12010-013-0233-z

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