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Is Lateral Pin Fixation for Displaced Supracondylar Fractures of the Humerus Better Than Crossed Pins in Children?

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Clinical Orthopaedics and Related Research®

Abstract

Background

Closed reduction and percutaneous pin fixation is considered standard management for displaced supracondylar fractures of the humerus in children. However, controversy exists regarding whether to use an isolated lateral entry or a crossed medial and lateral pinning technique.

Questions/purposes

We performed a meta-analysis of randomized controlled trials (RCTs) to compare (1) the risk of iatrogenic ulnar nerve injury caused by pin fixation, (2) the quality of fracture reduction in terms of the radiographic outcomes, and (3) function in terms of criteria of Flynn et al. and elbow ROM, and other surgical complications caused by pin fixation.

Methods

We searched PubMed, Embase, the Cochrane Library, and other unpublished studies without language restriction. Seven RCTs involving 521 patients were included. Two authors independently assessed the methodologic quality of the included studies with use of the Detsky score. The median Detsky quality score of the included trials was 15.7 points. Dichotomous variables were presented as risk ratios (RRs) or risk difference with 95% confidence intervals (CIs) and continuous data were measured as mean differences with 95% CI. Statistical heterogeneity between studies was formally tested with standard chi-square test and I2 statistic. For the primary objective, a funnel plot of the primary end point and Egger’s test were performed to detect publication bias.

Results

The pooled RR suggested that iatrogenic ulnar nerve injury was higher with the crossed pinning technique than with the lateral entry technique (RR, 0.30; 95% CI, 0.10–0.89). No publication bias was further detected. There were no statistical differences in radiographic outcomes, function, and other surgical complications. No significant heterogeneity was found in these pooled results.

Conclusions

We conclude that the crossed pinning fixation is more at risk for iatrogenic ulnar nerve injury than the lateral pinning technique. Therefore, we recommend the lateral pinning technique for supracondylar fractures of the humerus in children.

Level of Evidence

Level I, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

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Acknowledgments

We thank the professional staff of Tianjin Medical Information Center and Tianjin Medical Library for providing assistance. We also thank the patients and clinical researchers who were involved in the publications mentioned in our article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jia-Guo Zhao MD.

Additional information

Each author certifies that he or she, or a member of his or her immediate family, has no funding or commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.

All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research editors and board members are on file with the publication and can be viewed on request.

Clinical Orthopaedics and Related Research neither advocates nor endorses the use of any treatment, drug, or device. Readers are encouraged to always seek additional information, including FDA approval status, of any drug or device before clinical use.

This work was performed at Department of Orthopaedic Surgery, Tianjin Hospital, Tianjin, China.

Appendix 1. Detailed characteristics of included studies

Appendix 1. Detailed characteristics of included studies

Variable

Foead et al. [14]

Kocher et al. [28]

Tripuraneni et al. [54]

Vaidya [55]

Gaston et al. [16]

Anwar et al. [2]

Maity et al. [35]

Year

2004

2007

2009

2009

2010

2011

2012

Design type

RCT

RCT

Quasi-RCT

RCT

Quasi-RCT

RCT

RCT

Populations

 Number

  Lateral group

27

28

20

29

47

25

80

  Crossed group

28

24

20

31

57

25

80

 Age (years)

5.78

    

7.02

 

  Lateral group

 

6.1

4.3

5.8

5.7

 

6.12

  Crossed group

 

5.7

5.5

6.2

6.2

 

6.24

 Male: female

Unclear

 

Unclear

  

33:17

 

  Lateral group

 

10:18

 

21:8

22:25

 

51:29

  Crossed group

 

13:11

 

17:14

31:26

 

48:32

 Gartland type

II and III

III

II and III

III

III

II and III

II and III

 Inclusion criteria

Closed extension fracture; within 72 hours of injury

Closed extension fracture; within 48 hours of injury

No restriction for open, multiple and compound fracture (total 3 patients)

Closed fracture; within 96 hours of injury

Closed extension fracture; within 24 hours of injury

Closed fracture; within 72 hours of injury

Closed extension fracture; within 72 hours of injury

 Exclusion criteria

Multiple fracture; compound fracture; previous fracture

Multiple fracture; compound fracture; previous fracture; open reduction

Revision fixation cases

Multiple fracture; compound fracture; previous fracture; open reduction

Inadequate perioperative radiographs

Neurovascular complications; open reduction and internal fixation

Multiple fracture; compound fracture; previous fracture; open reduction

Interventions

  Lateral group

Closed reduction and two lateral pins

Closed reduction and two lateral pins

Closed reduction and two lateral pins; 8 patients with a third pin

Closed reduction and two or three lateral pins

Closed reduction and two lateral pins; 5 patients with a third pin; 3 open reductions

Closed reduction and two lateral pins

Closed reduction and two lateral pins

  Crossed group

Closed reduction and two crossed pins

Closed reduction and two crossed pins

Closed reduction and two crossed pins; 5 patients with a third pin; one open reduction

Closed reduction with one medial and one or two lateral pins

Closed reduction and two crossed pins; 8 patients with a third pin; 5 open reduction

Closed reduction and two crossed pins

Closed reduction and two crossed pins

Outcomes

 Radiographic outcomes

Change in carrying angle, Baumann angle, and medial epicondylar epiphyseal angle

Baumann, carrying and humerocapitellar angle; change in Baumann and Humerocapitellar angle; loss of reduction

Baumann angle, Humerotrochlear angle

Change in carrying angle, change in Baumann and Humerocapitellar angle; loss of reduction

Humerocapitellar angle; change in Baumann and Humerocapitellar angle; loss of reduction

Change in Baumann angle; loss of carrying angle; loss of metaphyseal diaphyseal angle

Baumann and carrying angle; change in Baumann angle; loss of carrying angle; loss of reduction

 Functional outcomes

Loss of extension and flexion

Range of motion; Flynn criteria; return to function

Range of motion

Range of motion; Flynn criteria; return to function

 

Flynn criteria; loss of extension and flexion

Range of motion; Flynn criteria

 Complications

Iatrogenic nerve injury; infection; vascular injury; compartment syndrome

Iatrogenic nerve injury; infection; reoperation

Iatrogenic nerve injury; infection

Iatrogenic nerve injury; infection; reoperation

Iatrogenic nerve injury; reoperation; compartment syndrome

Iatrogenic nerve injury; compartment syndrome

Iatrogenic nerve injury; infection

Followup

8.9 months

3 months

 

6 months

Unclear

6 months

3 months

  Lateral group

  

65.1 days

    

  Crossed group

  

54.6 days

    
  1. Quasi-RCTs were defined as those in which randomization is inadequately concealed (ie, patients are allocated according to known characteristics such as date of birth, hospital chart number, or day of presentation); RCT = randomized controlled trial.

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Zhao, JG., Wang, J. & Zhang, P. Is Lateral Pin Fixation for Displaced Supracondylar Fractures of the Humerus Better Than Crossed Pins in Children?. Clin Orthop Relat Res 471, 2942–2953 (2013). https://doi.org/10.1007/s11999-013-3025-4

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