Abstract
Background
Closed reduction and percutaneous pin fixation is considered standard management for displaced supracondylar fractures of the humerus in children. However, controversy exists regarding whether to use an isolated lateral entry or a crossed medial and lateral pinning technique.
Questions/purposes
We performed a meta-analysis of randomized controlled trials (RCTs) to compare (1) the risk of iatrogenic ulnar nerve injury caused by pin fixation, (2) the quality of fracture reduction in terms of the radiographic outcomes, and (3) function in terms of criteria of Flynn et al. and elbow ROM, and other surgical complications caused by pin fixation.
Methods
We searched PubMed, Embase, the Cochrane Library, and other unpublished studies without language restriction. Seven RCTs involving 521 patients were included. Two authors independently assessed the methodologic quality of the included studies with use of the Detsky score. The median Detsky quality score of the included trials was 15.7 points. Dichotomous variables were presented as risk ratios (RRs) or risk difference with 95% confidence intervals (CIs) and continuous data were measured as mean differences with 95% CI. Statistical heterogeneity between studies was formally tested with standard chi-square test and I2 statistic. For the primary objective, a funnel plot of the primary end point and Egger’s test were performed to detect publication bias.
Results
The pooled RR suggested that iatrogenic ulnar nerve injury was higher with the crossed pinning technique than with the lateral entry technique (RR, 0.30; 95% CI, 0.10–0.89). No publication bias was further detected. There were no statistical differences in radiographic outcomes, function, and other surgical complications. No significant heterogeneity was found in these pooled results.
Conclusions
We conclude that the crossed pinning fixation is more at risk for iatrogenic ulnar nerve injury than the lateral pinning technique. Therefore, we recommend the lateral pinning technique for supracondylar fractures of the humerus in children.
Level of Evidence
Level I, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
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Acknowledgments
We thank the professional staff of Tianjin Medical Information Center and Tianjin Medical Library for providing assistance. We also thank the patients and clinical researchers who were involved in the publications mentioned in our article.
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Appendix 1. Detailed characteristics of included studies
Appendix 1. Detailed characteristics of included studies
Variable | Foead et al. [14] | Kocher et al. [28] | Tripuraneni et al. [54] | Vaidya [55] | Gaston et al. [16] | Anwar et al. [2] | Maity et al. [35] |
---|---|---|---|---|---|---|---|
Year | 2004 | 2007 | 2009 | 2009 | 2010 | 2011 | 2012 |
Design type | RCT | RCT | Quasi-RCT | RCT | Quasi-RCT | RCT | RCT |
Populations | |||||||
Number | |||||||
Lateral group | 27 | 28 | 20 | 29 | 47 | 25 | 80 |
Crossed group | 28 | 24 | 20 | 31 | 57 | 25 | 80 |
Age (years) | 5.78 | 7.02 | |||||
Lateral group | 6.1 | 4.3 | 5.8 | 5.7 | 6.12 | ||
Crossed group | 5.7 | 5.5 | 6.2 | 6.2 | 6.24 | ||
Male: female | Unclear | Unclear | 33:17 | ||||
Lateral group | 10:18 | 21:8 | 22:25 | 51:29 | |||
Crossed group | 13:11 | 17:14 | 31:26 | 48:32 | |||
Gartland type | II and III | III | II and III | III | III | II and III | II and III |
Inclusion criteria | Closed extension fracture; within 72 hours of injury | Closed extension fracture; within 48 hours of injury | No restriction for open, multiple and compound fracture (total 3 patients) | Closed fracture; within 96 hours of injury | Closed extension fracture; within 24 hours of injury | Closed fracture; within 72 hours of injury | Closed extension fracture; within 72 hours of injury |
Exclusion criteria | Multiple fracture; compound fracture; previous fracture | Multiple fracture; compound fracture; previous fracture; open reduction | Revision fixation cases | Multiple fracture; compound fracture; previous fracture; open reduction | Inadequate perioperative radiographs | Neurovascular complications; open reduction and internal fixation | Multiple fracture; compound fracture; previous fracture; open reduction |
Interventions | |||||||
Lateral group | Closed reduction and two lateral pins | Closed reduction and two lateral pins | Closed reduction and two lateral pins; 8 patients with a third pin | Closed reduction and two or three lateral pins | Closed reduction and two lateral pins; 5 patients with a third pin; 3 open reductions | Closed reduction and two lateral pins | Closed reduction and two lateral pins |
Crossed group | Closed reduction and two crossed pins | Closed reduction and two crossed pins | Closed reduction and two crossed pins; 5 patients with a third pin; one open reduction | Closed reduction with one medial and one or two lateral pins | Closed reduction and two crossed pins; 8 patients with a third pin; 5 open reduction | Closed reduction and two crossed pins | Closed reduction and two crossed pins |
Outcomes | |||||||
Radiographic outcomes | Change in carrying angle, Baumann angle, and medial epicondylar epiphyseal angle | Baumann, carrying and humerocapitellar angle; change in Baumann and Humerocapitellar angle; loss of reduction | Baumann angle, Humerotrochlear angle | Change in carrying angle, change in Baumann and Humerocapitellar angle; loss of reduction | Humerocapitellar angle; change in Baumann and Humerocapitellar angle; loss of reduction | Change in Baumann angle; loss of carrying angle; loss of metaphyseal diaphyseal angle | Baumann and carrying angle; change in Baumann angle; loss of carrying angle; loss of reduction |
Functional outcomes | Loss of extension and flexion | Range of motion; Flynn criteria; return to function | Range of motion | Range of motion; Flynn criteria; return to function | Flynn criteria; loss of extension and flexion | Range of motion; Flynn criteria | |
Complications | Iatrogenic nerve injury; infection; vascular injury; compartment syndrome | Iatrogenic nerve injury; infection; reoperation | Iatrogenic nerve injury; infection | Iatrogenic nerve injury; infection; reoperation | Iatrogenic nerve injury; reoperation; compartment syndrome | Iatrogenic nerve injury; compartment syndrome | Iatrogenic nerve injury; infection |
Followup | 8.9 months | 3 months | 6 months | Unclear | 6 months | 3 months | |
Lateral group | 65.1 days | ||||||
Crossed group | 54.6 days |
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Zhao, JG., Wang, J. & Zhang, P. Is Lateral Pin Fixation for Displaced Supracondylar Fractures of the Humerus Better Than Crossed Pins in Children?. Clin Orthop Relat Res 471, 2942–2953 (2013). https://doi.org/10.1007/s11999-013-3025-4
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DOI: https://doi.org/10.1007/s11999-013-3025-4