Skip to main content
Log in

Compartment Syndrome of the Lower Leg and Foot

  • Symposium: Recent Advances in Foot and Ankle Surgery
  • Published:
Clinical Orthopaedics and Related Research®

Abstract

Compartment syndrome of the lower leg or foot, a severe complication with a low incidence, is mostly caused by high-energy deceleration trauma. The diagnosis is based on clinical examination and intracompartmental pressure measurement. The most sensitive clinical symptom of compartment syndrome is severe pain. Clinical findings must be documented carefully. A fasciotomy should be performed when the difference between compartment pressure and diastolic blood pressure is less than 30 mm Hg or when clinical symptoms are obvious. Once the diagnosis is made, immediate fasciotomy of all compartments is required. Fasciotomy of the lower leg can be performed either by one lateral incision or by medial and lateral incisions. The compartment syndrome of the foot requires thorough examination of all compartments with special focus on the calcaneal compartment. Depending on the injury, clinical examination, and compartment pressure, fasciotomy is recommended via a dorsal and/or medial plantar approach. Surgical management does not eliminate the risk of developing nerve and muscle dysfunction. When left untreated, poor outcomes with contractures, toe deformities, paralysis, and sensory neuropathy can be expected. In severe cases, amputation may be necessary.

Level of Evidence: Level III. See Guidelines for Authors for a complete description of levels of evidence.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Al Dadah OQ, Darrah C, Cooper A, Donell ST, Patel AD. Continuous compartment pressure monitoring vs. clinical monitoring in tibial diaphyseal fractures. Injury. 2008;39:1204–1209.

    Article  CAS  PubMed  Google Scholar 

  2. Anglen J, Banovetz J. Compartment syndrome in the well leg resulting from fracture-table positioning. Clin Orthop Relat Res. 1994;239–242.

  3. Askins G, Finley R, Parenti J, Bush D, Brotman S. High-energy roller injuries to the upper extremity. J Trauma. 1986;26:1127–1131.

    Article  CAS  PubMed  Google Scholar 

  4. Batra S, McMurtrie A, Sinha AK, Griffin S. Recurrent compartment syndrome of foot following calcaneal fracture. Foot Ankle Surg. 2007;13:154–156.

    Article  Google Scholar 

  5. Benejam CE, Potaczek SG. Unusual presentation of Lisfranc fracture dislocation associated with high-velocity sledding injury: a case report and review of the literature. J Med Case Reports. 2008;2:266.

    Article  PubMed  Google Scholar 

  6. Bong MR, Polatsch DB, Jazrawi LM, Rokito AS. Chronic exertional compartment syndrome: diagnosis and management. Bull Hosp Jt Dis. 2005;62:77–84.

    PubMed  Google Scholar 

  7. Bonutti PM, Bell GR. Compartment syndrome of the foot. A case report. J Bone Joint Surg Am. 1986;68:1449–1451.

    CAS  PubMed  Google Scholar 

  8. Burton AC. On the physical equilibrium of small blood vessels. Am J Physiol. 1951;164:319–329.

    CAS  PubMed  Google Scholar 

  9. Busch T, Sirbu H, Zenker D, Dalichau H. Vascular complications related to intraaortic balloon counterpulsation: An analysis of ten years experience. Thorac Cardiovasc Surg. 1997;45:55–59.

    Article  CAS  PubMed  Google Scholar 

  10. Cara JA, Narvaez A, Bertrand ML, Guerado E. Acute atraumatic compartment syndrome in the leg. Int Orthop. 1999;23:61–62.

    Article  CAS  PubMed  Google Scholar 

  11. Cascio BM, Wilckens JH, Ain MC, Toulson C, Frassica FJ. Documentation of acute compartment syndrome at an academic health-care center. J Bone Joint Surg Am. 2005;87:346–350.

    Article  PubMed  Google Scholar 

  12. Cooper GG. A Method of Single-Incision, 4 Compartment Fasciotomy of the Leg. Eur J Vasc Surg. 1992;6:659–661.

    Article  CAS  PubMed  Google Scholar 

  13. Court-Brown CM. Reamed intramedullary tibial nailing: an overview and analysis of 1106 cases. J Orthop Trauma. 2004;18:96–101.

    Article  CAS  PubMed  Google Scholar 

  14. Day LJ, Bovill EG, Trafton PG. Orthopedics. In: Way LW. Current Surgical Diagnosis and Treatment, 9th ed. East Norwalk, CT: Appleton and Lange; 1991:1038.

  15. Dayton P, Goldman FD, Barton E. Compartment pressure in the foot. Analysis of normal values and measurement technique. J Am Podiatr Med Assoc. 1990;80:521–525.

    CAS  PubMed  Google Scholar 

  16. de Fijter WM, Scheltinga MR, Luiting MG. Minimally invasive fasciotomy in chronic exertional compartment syndrome and fascial hernias of the anterior lower leg: short- and long-term results. Mil Med. 2006;171:399–403.

    PubMed  Google Scholar 

  17. DeLee JC, Stiehl JB. Open tibia fracture with compartment syndrome. Clin Orthop Relat Res. 1981;175–184.

  18. Due J, Nordstrand K. A simple technique for subcutaneous fasciotomy. Acta Chirurgica Scandinavica. 1987;153:521–522.

    PubMed  Google Scholar 

  19. Echtermeyer V. Compartment syndrome. Principles of therapy [in German]. Unfallchirurg. 1991;94:225–230.

    CAS  PubMed  Google Scholar 

  20. Echtermeyer V, Muhr G, Oestern HJ, Tscherne H. Surgical treatment of compartmental syndromes (author’s transl) [in German]. Unfallheilkunde. 1982;85:144–152.

    CAS  PubMed  Google Scholar 

  21. Finkelstein JA, Hunter GA, Hu RW. Lower limb compartment syndrome: course after delayed fasciotomy. J Trauma. 1996;40:342–344.

    Article  CAS  PubMed  Google Scholar 

  22. Fitzgerald AM, Gaston P, Wilson Y, Quaba A, McQueen MM. Long-term sequelae of fasciotomy wounds. Br J Plast Surg. 2000;53:690–693.

    Article  CAS  PubMed  Google Scholar 

  23. Friedrich JB, Shin AY. Management of forearm compartment syndrome. Hand Clin. 2007;23:245–54, vii.

    Article  PubMed  Google Scholar 

  24. Frink M, Geerling J, Hildebrand F, Knobloch K, Zech S, Droste P, Krettek C, Richter M. Etiology, treatment and long-term results of isolated midfoot fractures. Foot Ankle Surg. 2006;12:121–125.

    Article  Google Scholar 

  25. Frink M, Klaus AK, Kuther G, Probst C, Gosling T, Kobbe P, Hildebrand F, Richter M, Giannoudis PV, Krettek C, Pape HC. Long term results of compartment syndrome of the lower limb in polytraumatised patients. Injury. 2007;38:607–613.

    Article  PubMed  Google Scholar 

  26. Fuhrman FA, Crismon JM. Early changes in distribution of sodium, potassium and water in rabbit muscles following release of tourniquets. Am J Physiol. 1951;166:424–432.

    CAS  PubMed  Google Scholar 

  27. Fulkerson E, Razi A, Tejwani N. Review: acute compartment syndrome of the foot. Foot Ankle Int. 2003;24:180–187.

    PubMed  Google Scholar 

  28. Gerngross H, Rosenheimer M, Becker HP. Invasive measurement of compartment pressure based on piezo-resistance principles [in German]. Chirurg. 1991;62:832–833.

    CAS  PubMed  Google Scholar 

  29. Giannoudis PV, Nicolopoulos C, Dinopoulos H, Ng A, Adedapo S, Kind P. The impact of lower leg compartment syndrome on health related quality of life. Injury. 2002;33:117–121.

    Article  CAS  PubMed  Google Scholar 

  30. Goldman FD, Dayton PD, Hanson CJ. Compartment syndrome of the foot. J Foot Surg. 1990;29:37–43.

    CAS  PubMed  Google Scholar 

  31. Griffiths DL. The management of acute circulatory failure in an injured limb. J Bone Joint Surg Br. 1948;30:280–298.

    Google Scholar 

  32. Grodinsky M. A study of the fascial spaces of the foot and their bearing of infection. Surg Gynecol Obstet. 1929;49:737–751.

    Google Scholar 

  33. Guyton GP, Shearman CM, Saltzman CL. The compartments of the foot revisited. Rethinking the validity of cadaver infusion experiments. J Bone Joint Surg Br. 2001;83:245–249.

    Article  CAS  PubMed  Google Scholar 

  34. Harris IA, Kadir A, Donald G. Continuous compartment pressure monitoring for tibia fractures: does it influence outcome? J Trauma. 2006;60:1330–1335.

    Article  PubMed  Google Scholar 

  35. Heemskerk J, Kitslaar P. Acute compartment syndrome of the lower leg: Retrospective study on prevalence, technique, and outcome of fasciotomies. World J Surg. 2003;27:744–747.

    Article  PubMed  Google Scholar 

  36. Heppenstall RB, Scott R, Sapega A, Park YS, Chance B. A comparative study of the tolerance of skeletal muscle to ischemia. Tourniquet application compared with acute compartment syndrome. J Bone Joint Surg Am. 1986;68:820–828.

    CAS  PubMed  Google Scholar 

  37. Hildebrand O. Die Lehre von den ischämischen Muskellähmungen und Kontrakturen. Samml Klin Vorträge. 1906;122:437.

    Google Scholar 

  38. Ho GH, van Laarhoven CJ, Ottow RT. Compartment syndrome in both lower legs after prolonged surgery in the lithotomy position [in Dutch]. Ned Tijdschr Geneeskd. 1998;142:1210–1212.

    CAS  PubMed  Google Scholar 

  39. Jeffers RF, Tan HB, Nicolopoulos C, Kamath R, Giannoudis PV. Prevalence and patterns of foot injuries following motorcycle trauma. J Orthop Trauma. 2004;18:87–91.

    Article  CAS  PubMed  Google Scholar 

  40. Johnson SB, Weaver FA, Yellin AE, Kelly R, Bauer M. Clinical results of decompressive dermotomy-fasciotomy. Am J Surg. 1992;164:286–290.

    Article  CAS  PubMed  Google Scholar 

  41. Jowett A, Birks C, Blackney M. Chronic exertional compartment syndrome in the medial compartment of the foot. Foot Ankle Int. 2008;29:838–841.

    Article  PubMed  Google Scholar 

  42. Kamel R, Sakla FB. Anatomical compartments of the sole of the human foot. Anat Rec. 1961;140:57–60.

    Article  Google Scholar 

  43. Kunkel MG, Lynn RB. The anterior tibial compartment syndrome. Can J Surg. 1958;1:212–217.

    CAS  PubMed  Google Scholar 

  44. Ling ZX, Kumar VP. The myofascial compartments of the foot: a cadaver study. J Bone Joint Surg Br. 2008;90:1114–1118.

    Article  CAS  PubMed  Google Scholar 

  45. Lokiec F, Siev-Ner I, Pritsch M. Chronic compartment syndrome of both feet. J Bone Joint Surg Br. 1991;73:178–179.

    CAS  PubMed  Google Scholar 

  46. Manoli A, Weber TG. Fasciotomy of the foot: an anatomical study with special reference to release of the calcaneal compartment. Foot Ankle. 1990;10:267–275.

    PubMed  Google Scholar 

  47. Matsen FA, III. Compartmental syndrome. An unified concept. Clin Orthop Relat Res. 1975;8–14.

  48. Matsen FA, III, Winquist RA, Krugmire RB, Jr. Diagnosis and management of compartmental syndromes. J Bone Joint Surg Am. 1980;62:286–291.

    PubMed  Google Scholar 

  49. Matsuoka T, Yoshioka T, Tanaka H, Ninomiya N, Oda J, Sugimoto H, Yokota J. Long-term physical outcome of patients who suffered crush syndrome after the 1995 Hanshin-Awaji earthquake: prognostic indicators in retrospect. J Trauma. 2002;52:33–39.

    Article  PubMed  Google Scholar 

  50. Maurel B, Brilhault J, Martinez R, Lermusiaux P. Compartment syndrome with foot ischemia after inversion injury of the ankle. J Vasc Surg. 2007;46:369–371.

    Article  PubMed  Google Scholar 

  51. McQueen MM, Christie J, Court-Brown CM. Compartment pressures after intramedullary nailing of the tibia. J Bone Joint Surg Br. 1990;72:395–397.

    CAS  PubMed  Google Scholar 

  52. McQueen MM, Christie J, Court-Brown CM. Acute compartment syndrome in tibial diaphyseal fractures. J Bone Joint Surg Br. 1996;78:95–98.

    CAS  PubMed  Google Scholar 

  53. McQueen MM, Court-Brown CM. Compartment monitoring in tibial fractures. The pressure threshold for decompression. J Bone Joint Surg Br. 1996;78:99–104.

    CAS  PubMed  Google Scholar 

  54. McQueen MM, Gaston P, Court-Brown. Acute compartment syndrome - Who is at risk? J Bone Joint Surg Br. 2000;82:200–203.

    Article  CAS  PubMed  Google Scholar 

  55. McQuillan WM, Nolan B. Ischaemia complicating injury. A report of thirty-seven cases. J Bone Joint Surg Br. 1968;50:482–492.

    CAS  PubMed  Google Scholar 

  56. Middleton DK, Johnson JE, Davies JF. Exertional compartment syndrome of bilateral feet: a case report. Foot Ankle Int. 1995;16:95–96.

    CAS  PubMed  Google Scholar 

  57. Mithofer K, Lhowe DW, Vrahas MS, Altman DT, Altman GT. Clinical spectrum of acute compartment syndrome of the thigh and its relation to associated injuries. Clin Orthop Relat Res. 2004;223–229.

  58. Miyabe M, Sato S. The effect of head-down tilt position on arterial blood pressure after spinal anesthesia for cesarean delivery. Reg Anesth. 1997;22:239–242.

    Article  CAS  PubMed  Google Scholar 

  59. Mollica MB. Chronic exertional compartment syndrome of the foot. A case report. J Am Podiatr Med Assoc. 1998;88:21–24.

    CAS  PubMed  Google Scholar 

  60. Moses TA, Kreder KJ, Thrasher JB. Compartment syndrome: an unusual complication of the lithotomy position. Urology. 1994;43:746–747.

    Article  CAS  PubMed  Google Scholar 

  61. Mouhsine E, Garofalo R, Moretti B, Gremion G, Akiki A. Two minimal incision fasciotomy for chronic exertional compartment syndrome of the lower leg. Knee Surg Sports Traumatol Arthrosc. 2006;14:193–197.

    Article  CAS  PubMed  Google Scholar 

  62. Mubarak S, Owen CA. Compartmental syndrome and its relation to the crush syndrome: A spectrum of disease. A review of 11 cases of prolonged limb compression. Clin Orthop Relat Res. 1975;81–89.

  63. Muller GP, Masquelet AC. Chronic compartment syndrome of the foot. A case report [in French]. Rev Chir Orthop Reparatrice Appar Mot. 1995;81:549–552.

    CAS  PubMed  Google Scholar 

  64. Mustard WT, Simmons EH. Experimental arterial spasm in the lower extremities produced by traction. J Bone Joint Surg Br. 1953;35:437–441.

    PubMed  Google Scholar 

  65. Myerson M. Acute compartment syndromes of the foot. Bull Hosp Jt Dis Orthop Inst. 1987;47:251–261.

    CAS  PubMed  Google Scholar 

  66. Myerson M. Diagnosis and treatment of compartment syndrome of the foot. Orthopedics. 1990;13:711–717.

    CAS  PubMed  Google Scholar 

  67. Myerson M, Manoli A. Compartment syndromes of the foot after calcaneal fractures. Clin Orthop Relat Res. 1993;142–150.

  68. Myerson MS. Experimental decompression of the fascial compartments of the foot–the basis for fasciotomy in acute compartment syndromes. Foot Ankle. 1988;8:308–314.

    CAS  PubMed  Google Scholar 

  69. Myerson MS. Management of compartment syndromes of the foot. Clin Orthop Relat Res. 1991;239–248.

  70. Nassif JM, Gorczyca JT, Cole JK, Pugh KJ, Pienkowski D. Effect of acute reamed versus unreamed intramedullary nailing on compartment pressure when treating closed tibial shaft fractures: a randomized prospective study. J Orthop Trauma. 2000;14:554–558.

    Article  CAS  PubMed  Google Scholar 

  71. Ogunlusi JD, Oginni LM, Ikem IC. Normal leg compartment pressures in adult Nigerians using the Whitesides method. Iowa Orthop J. 2005;25:200–202.

    PubMed  Google Scholar 

  72. Olson SA, Glasgow RR. Acute compartment syndrome in lower extremity musculoskeletal trauma. J Am Acad Orthop Surg. 2005;13:436–444.

    PubMed  Google Scholar 

  73. Paaske WP, Bagl P, Lorentzen JE, Olgaard K. Plasma exchange after revascularization compartment syndrome with acute toxic nephropathy caused by rhabdomyolysis. J Vasc Surg. 1988;7:757–758.

    Article  CAS  PubMed  Google Scholar 

  74. Reach JS, Jr., Amrami KK, Felmlee JP, Stanley DW, Alcorn JM, Turner NS, Carmichael SW. Anatomic compartments of the foot: a 3-Tesla magnetic resonance imaging study. Clin Anat. 2007;20:201–208.

    Article  PubMed  Google Scholar 

  75. Richter J, Schulze W, Klaas A, Clasbrummel B, Muhr G. Compartment syndrome of the foot: an experimental approach to pressure measurement and release. Arch Orthop Trauma Surg. 2008;128:199–204.

    Article  PubMed  Google Scholar 

  76. Richter M, Wippermann B, Krettek C, Schratt HE, Hufner T, Therman H. Fractures and fracture dislocations of the midfoot: occurrence, causes and long-term results. Foot Ankle Int. 2001;22:392–398.

    CAS  PubMed  Google Scholar 

  77. Rorabeck CH. A practical approach to compartmental syndrome. Part III. Management. Instr Course Lect. 1983;32:102–113.

    CAS  PubMed  Google Scholar 

  78. Santi MD, Botte MJ. Volkmann’s ischemic contracture of the foot and ankle: evaluation and treatment of established deformity. Foot Ankle Int. 1995;16:368–377.

    CAS  PubMed  Google Scholar 

  79. Schachtrupp A, Jansen M, Bertram P, Kuhlen R, Schumpelick V. [Abdominal compartment syndrome: significance, diagnosis and treatment]. Anaesthesist. 2006;55:660–667.

    Article  CAS  PubMed  Google Scholar 

  80. Schepsis AA, Martini D, Corbett M. Surgical management of exertional compartment syndrome of the lower leg. Long-term followup. Am J Sports Med. 1993;21:811–817.

    Article  CAS  PubMed  Google Scholar 

  81. Schwartz JT, Jr., Brumback RJ, Lakatos R, Poka A, Bathon GH, Burgess AR. Acute compartment syndrome of the thigh. A spectrum of injury. J Bone Joint Surg Am. 1989;71:392–400.

    PubMed  Google Scholar 

  82. Seiler JG, III, Womack S, De L’Aune WR, Whitesides TE, Hutton WC. Intracompartmental pressure measurements in the normal forearm. J Orthop Trauma. 1993;7:414–416.

    Article  PubMed  Google Scholar 

  83. Seiler R, Guziec G. Chronic compartment syndrome of the feet. A case report. J Am Podiatr Med Assoc. 1994;84:91–94.

    CAS  PubMed  Google Scholar 

  84. Shah SN, Miller BS, Kuhn JE. Chronic exertional compartment syndrome. Am J Orthop. 2004;33:335–341.

    PubMed  Google Scholar 

  85. Sharma H, Rana B, Naik M. Bipedal compartment syndrome folowing bilateral intra-articular calcaneal fractures. Foot Ankle Surg. 2004;10:93–96.

    Article  Google Scholar 

  86. Silas SI, Herzenberg JE, Myerson MS, Sponseller PD. Compartment syndrome of the foot in children. J Bone Joint Surg Am. 1995;77:356–361.

    CAS  PubMed  Google Scholar 

  87. Starosta D, Sacchetti AD, Sharkey P. Calcaneal fracture with compartment syndrome of the foot. Ann Emerg Med. 1988;17:856–858.

    Article  CAS  PubMed  Google Scholar 

  88. Sterk J, Schierlinger M, Gerngross H, Willy C. Compartment pressure measurement of acute compartment syndrome - results of a survey in Germany to measurement technique and pressure [in German]. Unfallchirurg. 2001;104:119–126.

    Article  CAS  PubMed  Google Scholar 

  89. Tzortziou V, Maffulli N, Padhiar N. Diagnosis and management of chronic exertional compartment syndrome (CECS) in the United Kingdom. Clin J Sport Med. 2006;16:209–213.

    Article  PubMed  Google Scholar 

  90. Ulmer T. The clinical diagnosis of compartment syndrome of the lower leg: are clinical findings predictive of the disorder? J Orthop Trauma. 2002;16:572–577.

    Article  PubMed  Google Scholar 

  91. Vaillancourt C, Shrier I, Vandal A, Falk M, Rossignol M, Vernec A, Somogyi D. Acute compartment syndrome: How long before muscle necrosis occurs? CJEM. 2004;6:147–154.

    PubMed  Google Scholar 

  92. Verleisdonk EJ, Schmitz RF, van der Werken C. Long-term results of fasciotomy of the anterior compartment in patients with exercise-induced pain in the lower leg. Int J Sports Med. 2004;25:224–229.

    Article  CAS  PubMed  Google Scholar 

  93. Volkmann R. Die ischämischen Muskellähmungen und Kontracturen. Zentralbl Chir. 1881;8:801–803.

    Google Scholar 

  94. Whitesides TE, Jr., Haney TC, Harada H, Holmes HE, Morimoto K. A simple method for tissue pressure determination. Arch Surg. 1975;110:1311–1313.

    PubMed  Google Scholar 

  95. Willy C, Sterk J, Völker HU, Sommer C, Weber F, Trentz O, Gerngross H. Acute compartment syndrome. Results of a clinical investigation of pressure and time thresholds for emergency fasciotomy [in German]. Unfallchirurg. 2001;104:381–391.

    Article  CAS  PubMed  Google Scholar 

  96. Yamaguchi S, Viegas SF. Causes of upper extremity compartment syndrome. Hand Clin. 1998;14:365–370, viii.

    CAS  PubMed  Google Scholar 

  97. Zelle BA, Brown SR, Panzica M, Lohse R, Sittaro NA, Krettek C, Pape HC. The impact of injuries below the knee joint on the long-term functional outcome following polytrauma. Injury. 2005;36:169–177.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael Frink MD.

Additional information

Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.

This work was performed at Hannover Medical School, Hannover, Germany.

About this article

Cite this article

Frink, M., Hildebrand, F., Krettek, C. et al. Compartment Syndrome of the Lower Leg and Foot. Clin Orthop Relat Res 468, 940–950 (2010). https://doi.org/10.1007/s11999-009-0891-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11999-009-0891-x

Keywords

Navigation