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Case Report: Histologic Study of a Human Epiphyseal Transplant at 3 Years after Implantation

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Clinical Orthopaedics and Related Research®

Abstract

A 5-year-old boy underwent surgical excision of a Ewing’s sarcoma of the proximal femur. Reconstruction was performed using an ipsilateral vascularized epiphyseal transplant and a femoral allograft. Local recurrence of the tumor necessitated hip disarticulation 3 years after the initial procedure. We then performed a histologic analysis of the transplant. The growth plate was still normal in structure but had richly vascularized hyperplastic layers. We observed bridging between the articular cartilage and the growth plate.

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Authors and Affiliations

  1. Department of Pediatric Orthopaedic Surgery, Hôpital des Enfants, Toulouse, France

    J. Sales de Gauzy MD, F. Accadbled MD, PhD & A. Abid MD

  2. Department of Pathology, Toulouse Rangueil University Hospital, Toulouse, France

    A. Gomez Brouchet MD

  3. Service de Chirurgie Orthopédique et Traumatologique, Hôpital des Enfants, 330, avenue de Grande Bretagne, 31059, Toulouse Cedex 9, France

    F. Accadbled MD, PhD

Authors
  1. J. Sales de Gauzy MD
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  2. F. Accadbled MD, PhD
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  3. A. Gomez Brouchet MD
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  4. A. Abid MD
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Corresponding author

Correspondence to F. Accadbled MD, PhD.

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Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.

Each author certifies that his or her institution has approved the reporting of this case report, that all investigations were conducted in conformity with ethical principles of research, and that informed consent for participation in the study was obtained.

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Sales de Gauzy, J., Accadbled, F., Gomez Brouchet, A. et al. Case Report: Histologic Study of a Human Epiphyseal Transplant at 3 Years after Implantation. Clin Orthop Relat Res 467, 1915–1920 (2009). https://doi.org/10.1007/s11999-009-0723-z

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  • DOI: https://doi.org/10.1007/s11999-009-0723-z

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