Skip to main content

Advertisement

Log in

Complications and Surveillance After Bariatric Surgery

  • Neurologic Manifestations of Systemic Disease (A Pruitt, Section Editor)
  • Published:
Current Treatment Options in Neurology Aims and scope Submit manuscript

Opinion statement

Bariatric surgery represents a durable and safe treatment modality for morbid obesity. Bariatric surgery results in weight loss by one of two—and possibly both—primary mechanisms, reducing the amount of tolerable intake (restrictive) and reducing the amount of nutrients absorbed by bypassing absorptive intestine (malabsorptive). These procedures have consistently demonstrated superior resolution of obesity and many associated co-morbid conditions as compared to medical management. Beyond the periprocedural complications of surgery, there are longitudinal risks such as weight regain, anatomic complications, and micronutrient deficiencies. Complications related to the anatomic alteration after bariatric surgery include internal herniation, marginal ulcers, dumping syndrome, and gastric band-related complications. Physicians who take care of bariatric patients at any point in their post-operative care must be vigilant for these complications, as they may necessitate urgent intervention or re-operation. Micronutrient deficiencies, which commonly occur after malabsorptive procedures, may present with a wide range of symptoms—including neuropathies, anemia, poor wound healing, and hair loss, among others. Deficiencies of vitamins and minerals frequently result in the need for long-term supplementation and may necessitate intravenous repletion when severe. Bariatric surgery may also alter the absorption of commonly prescribed medications, including anti-psychotic medications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among us adults, 1999–2010. JAMA. 2012;307(5):491–7.

    Article  PubMed  Google Scholar 

  2. Consensus Development Conference Panel. Gastrointestinal surgery for severe obesity. Ann Intern Med. 1991;115(12):956–61.

  3. Sjöström L, Narbro K, Sjöström CD, Karason K, Larsson B, Wedel H, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007;357(8):741–52.

    Article  PubMed  Google Scholar 

  4. Ikramuddin S, Korner J, Lee W, et al. Roux-en-y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the diabetes surgery study randomized clinical trial. JAMA. 2013;309(21):2240–9.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  5. Courcoulas AP, Belle SH, Neiberg RH, et al. Three-year outcomes of bariatric surgery vs lifestyle intervention for type 2 diabetes mellitus treatment: A randomized clinical trial. JAMA Surg. 2015;150(10):931–40.

  6. Ryan DH, Johnson WD, Myers VH, Prather TL, McGlone MM, Rood J, et al. Nonsurgical weight loss for extreme obesity in primary care settings: results of the Louisiana Obese Subjects Study. Arch Intern Med. 2010;170(2):146–54.

    Article  CAS  PubMed  Google Scholar 

  7. Reames BN, Finks JF, Bacal D, Carlin AM, Dimick JB. Changes in bariatric surgery procedure use in Michigan, 2006–2013. JAMA. 2014;312(9):959–61.

    Article  PubMed Central  PubMed  Google Scholar 

  8. Campos GM, Rabl C, Roll GR, et al. Better weight loss, resolution of diabetes, and quality of life for laparoscopic gastric bypass vs banding: results of a 2-cohort pair-matched study. Arch Surg. 2011;146(2):149–55.

    Article  PubMed  Google Scholar 

  9. DeMaria EJ. Bariatric surgery for morbid obesity. N Engl J Med. 2007;356(21):2176–83.

    Article  CAS  PubMed  Google Scholar 

  10. Iannelli A, Dainese R, Piche T, Facchiano E, Gugenheim J. Laparoscopic sleeve gastrectomy for morbid obesity. World J Gastroenterol : WJG. 2008;14(6):821–7.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Moy J, Pomp A, Dakin G, Parikh M, Gagner M. Laparoscopic sleeve gastrectomy for morbid obesity. Am J Surg. 2008;196(5):e56–9.

    Article  PubMed  Google Scholar 

  12. Bohdjalian A, Langer F, Shakeri-Leidenmühler S, Gfrerer L, Ludvik B, Zacherl J, et al. Sleeve gastrectomy as sole and definitive bariatric procedure: 5-year results for weight loss and Ghrelin. Obes Surg. 2010;20(5):535–40. English. This is an important paper describing the outcomes after the VSG.

    Article  PubMed  Google Scholar 

  13. Ryan KK, Tremaroli V, Clemmensen C, Kovatcheva-Datchary P, Myronovych A, Karns R, et al. FXR is a molecular target for the effects of vertical sleeve gastrectomy. Nature. 2014;509(7499):183–8.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  14. O’Brien PE, MacDonald L, Anderson M, Brennan L, Brown WA. Long-term outcomes after bariatric surgery: fifteen-year follow-up of adjustable gastric banding and a systematic review of the bariatric surgical literature. Ann Surg. 2013;257(1):87–94. This is an important outcome focused paper on the long term co-morbidity resolution resulting from bariatric surgery.

    Article  PubMed  Google Scholar 

  15. Tevis S, Garren M, Gould J. Revisional surgery for failed vertical-banded gastroplasty. Obes Surg. 2011;21(8):1220–4. English.

    Article  PubMed  Google Scholar 

  16. Prachand VN, DaVee RT, Alverdy JC. Duodenal switch provides superior weight loss in the super-obese (BMI ≥50kg/m(2)) compared with gastric bypass. Ann Surg. 2006;244(4):611–9.

    PubMed Central  PubMed  Google Scholar 

  17. Booth H, Khan O, Prevost T, Reddy M, Dregan A, Charlton J, et al. Incidence of type 2 diabetes after bariatric surgery: population-based matched cohort study. Lancet Diabetes Endocrinol. 2014;2(12):963–8.

    Article  PubMed  Google Scholar 

  18. Dorman R, Abraham A, Al-Refaie W, Parsons H, Ikramuddin S, Habermann E. Bariatric surgery outcomes in the elderly: an ACS NSQIP study. J Gastrointest Surg. 2012;16(1):35–44. English.

    Article  PubMed  Google Scholar 

  19. Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292(14):1724–37.

    Article  CAS  PubMed  Google Scholar 

  20. Sjöström L, Lindroos A-K, Peltonen M, Torgerson J, Bouchard C, Carlsson B, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683–93.

    Article  PubMed  Google Scholar 

  21. Sjöström L, Peltonen M, Jacobson P, et al. Bariatric surgery and long-term cardiovascular events. JAMA. 2012;307(1):56–65.

    Article  PubMed  Google Scholar 

  22. Arterburn DE, Olsen MK, Smith VA, et al. Association between bariatric surgery and long-term survival. JAMA. 2015;313(1):62–70.

    Article  CAS  PubMed  Google Scholar 

  23. Sugerman HJ, Felton 3rd WL, Salvant Jr JB, Sismanis A, Kellum JM. Effects of surgically induced weight loss on idiopathic intracranial hypertension in morbid obesity. Neurology. 1995;45(9):1655–9.

    Article  CAS  PubMed  Google Scholar 

  24. Sugerman HJ, Felton WL, Sismanis A, Kellum JM, DeMaria EJ, Sugerman EL. Gastric surgery for pseudotumor cerebri associated with severe obesity. Ann Surg. 1999;229(5):634.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  25. Aurora A, Khaitan L, Saber A. Sleeve gastrectomy and the risk of leak: a systematic analysis of 4,888 patients. Surg Endosc. 2012;26(6):1509–15. English.

    Article  PubMed  Google Scholar 

  26. Smith MD, Adeniji A, Wahed AS, Patterson E, Chapman W, Courcoulas AP, et al. Technical factors associated with anastomotic leak after Roux–en–Y gastric bypass. Surg Obes Relat Dis. 2015;11(2):313–20.

    Article  PubMed  Google Scholar 

  27. Moon RC, Teixeira AF, Goldbach M, Jawad MA. Management and treatment outcomes of marginal ulcers after Roux-en-Y gastric bypass at a single high volume bariatric center. Surg Obes Relat Dis. 2014;10(2):229–34.

    Article  PubMed  Google Scholar 

  28. Rasmussen JJ, Fuller W, Ali MR. Marginal ulceration after laparoscopic gastric bypass: an analysis of predisposing factors in 260 patients. Surg Endosc. 2007;21(7):1090–4. English.

    Article  CAS  PubMed  Google Scholar 

  29. Ukleja A. Dumping syndrome: pathophysiology and treatment. Nutr Clin Pract. 2005;20(5):517–25.

    Article  PubMed  Google Scholar 

  30. Carrodeguas L, Szomstein S, Zundel N, Lo Menzo E, Rosenthal R. Gastrojejunal anastomotic strictures following laparoscopic Roux-en-Y gastric bypass surgery: analysis of 1291 patients. Surg Obes Relat Dis. 2006;2(2):92–7.

    Article  PubMed  Google Scholar 

  31. Takata MC, Ciovica R, Cello JP, Posselt AM, Rogers SJ, Campos GM. Predictors, treatment, and outcomes of gastrojejunostomy stricture after gastric bypass for morbid obesity. Obes Surg. 2007;17(7):878–84.

    Article  PubMed  Google Scholar 

  32. Higa K, Ho T, Boone K. Internal hernias after laparoscopic Roux-en-Y gastric bypass: incidence. Treatment and prevention. Obes Surg. 2003;13(3):350–4. English.

    Article  PubMed  Google Scholar 

  33. Eid I, Birch DW, Sharma AM, Sherman V, Karmali S. Complications associated with adjustable gastric banding for morbid obesity: a surgeon’s guide. Can J Surg. 2011;54(1):61–6.

    Article  PubMed Central  PubMed  Google Scholar 

  34. Brown WA, Egberts KJ, Franke-Richard D, Thodiyil P, Anderson ML, O’Brien PE. Erosions after laparoscopic adjustable gastric banding: diagnosis and management. Ann Surg. 2013;257(6):1047–52.

    Article  PubMed  Google Scholar 

  35. MacLean LD, Rhode BM, Sampalis J, Forse RA. Results of the surgical treatment of obesity. Am J Surg. 1993;165(1):155–62.

    Article  CAS  PubMed  Google Scholar 

  36. Carter PR, LeBlanc KA, Hausmann MG, Kleinpeter KP, de Barros SN, Jones SM. Association between gastroesophageal reflux disease and laparoscopic sleeve gastrectomy. Surg Obes Relat Dis. 2011;7(5):569–72.

    Article  PubMed  Google Scholar 

  37. Patterson EJ, Davis DG, Khajanchee Y, Swanström LL. Comparison of objective outcomes following laparoscopic Nissen fundoplication versus laparoscopic gastric bypass in the morbidly obese with heartburn. Surg Endosc Other Interv Tech. 2003;17(10):1561–5. English.

    Article  CAS  Google Scholar 

  38. Berger JR. The neurological complications of bariatric surgery. Arch Neurol. 2004;61(8):1185–9.

    PubMed  Google Scholar 

  39. Bal BS, Finelli FC, Shope TR, Koch TR. Nutritional deficiencies after bariatric surgery. Nat Rev Endocrinol. 2012;8(9):544–56.

    Article  CAS  PubMed  Google Scholar 

  40. Shankar P, Boylan M, Sriram K. Micronutrient deficiencies after bariatric surgery. Nutrition. 2010;26(11–12):1031–7.

    Article  CAS  PubMed  Google Scholar 

  41. Tack J, Deloose E. Complications of bariatric surgery: dumping syndrome, reflux and vitamin deficiencies. Best Pract Res Clin Gastroenterol. 2014;28(4):741–9. This article reviews the many micronutrient deficiencies associated with Bariatric surgery.

    Article  CAS  PubMed  Google Scholar 

  42. Levinson R, Silverman JB, Catella JG, Rybak I, Jolin H, Isom K. Pharmacotherapy prevention and management of nutritional deficiencies post Roux-en-Y gastric bypass. Obes Surg. 2013;23(7):992–1000. Another excellent review of micronutrient deficiencies associated with bariatric surgery and their potential complications.

    Article  PubMed  Google Scholar 

  43. Kumar N. Copper deficiency myelopathy (human swayback). Mayo Clin Proc. 2006;81(10):1371–84.

    Article  CAS  PubMed  Google Scholar 

  44. Juhasz-Pocsine K, Rudnicki SA, Archer RL, Harik SI. Neurologic complications of gastric bypass surgery for morbid obesity. Neurology. 2007;68(21):1843–50.

    Article  PubMed  Google Scholar 

  45. Dahlquist NR, Perrault J, Callaway CW, Jones JD. d-lactic acidosis and encephalopathy after jejunoileostomy: response to overfeeding and to fasting in humans. Mayo Clin Proc. 1984;59(3):141–5.

    Article  CAS  PubMed  Google Scholar 

  46. Hamad GG, Helsel JC, Perel JM, Kozak GM, McShea MC, Hughes C, et al. The effect of gastric bypass on the pharmacokinetics of serotonin reuptake inhibitors. Am J Psychiatry. 2012;169(3):256–63.

    Article  PubMed Central  PubMed  Google Scholar 

  47. Seaman JS, Bowers SP, Dixon P, Schindler L. Dissolution of common psychiatric medications in a Roux-en-Y gastric bypass model. Psychosomatics. 2005;46(3):250–3.

    Article  PubMed  Google Scholar 

  48. Pournaras D, Footitt D, Mahon D, Welbourn R. Reduced phenytoin levels in an epileptic patient following Roux-en-Y gastric bypass for obesity. Obes Surg. 2011;21(5):684–5. English.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kristoffel R. Dumon MD.

Ethics declarations

Conflict of Interest

The authors declare that they have no competing interests.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

This article is part of the Topical Collection on Neurologic Manifestations of Systemic Disease

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Concors, S.J., Ecker, B.L., Maduka, R. et al. Complications and Surveillance After Bariatric Surgery. Curr Treat Options Neurol 18, 5 (2016). https://doi.org/10.1007/s11940-015-0383-0

Download citation

  • Published:

  • DOI: https://doi.org/10.1007/s11940-015-0383-0

Keywords

Navigation