Opinion statement
The treatment of hypertension in coarctation of the aorta (CoA) is ideally managed by early surgical or transcatheter repair to reduce the risk of irreversible aortopathy and refractory hypertension, in addition to other associated sequelae including premature coronary artery disease; stroke; aortic aneurysm, dissection, and rupture; infective endocarditis; and heart failure. The choice of surgical or transcatheter repair is dependent on individual patient considerations. Medical therapy for hypertension due to CoA parallels treatment of essential hypertension with beta blockers, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers as first-line agents.
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Dr. Stefanescu Schmidt was supported in the manuscript preparation by the National Institutes of Health T32HL007604 training grant in Cardiovascular research. The manuscript contents are solely the responsibility of the authors and do not necessarily represent the official views of NIH.
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This article is part of the Topical Collection on Adult Congenital Heart Disease
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Nakamura, K., Stefanescu Schmidt, A. Treatment of Hypertension in Coarctation of the Aorta. Curr Treat Options Cardio Med 18, 40 (2016). https://doi.org/10.1007/s11936-016-0462-x
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DOI: https://doi.org/10.1007/s11936-016-0462-x