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Cardiac Complications of Chemotherapy: Role of Imaging

  • Cardio-oncology (S Francis, Section Editor)
  • Published:
Current Treatment Options in Cardiovascular Medicine Aims and scope Submit manuscript

Opinion Statement

New advances in cancer diagnosis and treatment have increased survival rates in patients with cancer. In parallel with this increase in the number of cancer survivors is an increasing prevalence of cardiac complications from cancer treatment. Chemotherapy-induced cardiac dysfunction is a major contributor to adverse morbidity and mortality rates in cancer patients. Evidence suggests that both clinical symptoms and the traditional left ventricular ejection fraction (LVEF) may lack sensitivity as measures of cardiotoxicity. The early identification of subclinical LV dysfunction is becoming increasingly important, as this may allow cancer patients and their physicians to make informed decisions about therapeutic options. The features of echocardiography make it a useful tool in the diagnosis and monitoring of cardiotoxicity. This review will examine the role of cardiac imaging in detecting cardiotoxicity, focusing primarily on the conventional and more recent echocardiographic approaches for assessing subclinical cardiotoxicity.

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Conflict of Interest

Dr. Timothy C. Tan is supported by an American Society of Echocardiography Career Development Award and the Robert and Elizabeth Albert Study Grant (Royal Australasian College of Physicians).

Dr. Marielle Scherrer-Crosbie is supported by an investigator-initiated grant from Susan G. Komen for the Cure Foundation, the Claflin Distinguished Scholar Award, and a Clinical Innovation Award from MGH.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Cardiac Ultrasound Laboratory, Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA

    Timothy C. Tan MD, PhD & Marielle Scherrer-Crosbie MD, PhD

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  1. Timothy C. Tan MD, PhD
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  2. Marielle Scherrer-Crosbie MD, PhD
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Correspondence to Marielle Scherrer-Crosbie MD, PhD.

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This article is part of the Topical Collection on Cardio-oncology

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Tan, T.C., Scherrer-Crosbie, M. Cardiac Complications of Chemotherapy: Role of Imaging. Curr Treat Options Cardio Med 16, 296 (2014). https://doi.org/10.1007/s11936-014-0296-3

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  • DOI: https://doi.org/10.1007/s11936-014-0296-3

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