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The Effect of Shift Work on Urogenital Disease: a Systematic Review

  • Andrology and Infertility (L Lipshultz, Section Editor)
  • Published:
Current Urology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Non-standard shift work schedules negatively impact the overall health of shift workers, and several studies have shown that shift work, specifically, is detrimental to urogenital health. The aims of this study are to systematically review the literature and determine the effect of shift work on the outcomes of hypogonadism, male infertility, lower urinary tract symptoms, and urogenital cancers.

Recent Findings

Recent evidence supports associations between non-standard shift work and an increase in the frequency of prostate cancer and the severity of erectile dysfunction, lower urinary tract symptoms, and hypogonadal symptoms, as well as worsening of semen parameters and fertility. These associations are strengthened by the presence of shift work sleep disorder (SWSD) which affects up to 20% of shift workers. No studies have assessed the impact of shift work on the frequency or severity of nephrolithiasis, interstitial cystitis, pelvic pain, prostatitis, or urinary tract infections.

Summary

Non-standard shift work has been associated with a variety of negative health outcomes and urologic complications, especially with concurrent shift work sleep disorder. Recognition of these elevated risks among shift workers can aid in more effective screening for urologic conditions.

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Authors and Affiliations

  1. Baylor College of Medicine, Houston, TX, USA

    Nanfu Deng & Taylor P. Kohn

  2. Tulane University School of Medicine, New Orleans, LA, USA

    Nora M. Haney

  3. Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA

    Alexander W. Pastuszak & Larry I. Lipshultz

  4. Scott Department of Urology, Baylor College of Medicine, 6624 Fannin Street Suite 1700, Houston, TX, 77030, USA

    Alexander W. Pastuszak & Larry I. Lipshultz

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  1. Nanfu Deng
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  4. Alexander W. Pastuszak
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  5. Larry I. Lipshultz
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Correspondence to Larry I. Lipshultz.

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Conflict of Interest

Nanfu Deng, Nora M Haney, and Larry I. Lipshultz each declare no potential conflicts of interest.

Taylor P. Kohn is funded by the AUA Urology Care Foundation Summer Medical Student Award.

Alexander W. Pastuszak is a National Institutes of Health K12 Scholar supported by a Male Reproductive Health Research Career Development Physician-Scientist Award (HD073917–01) from the Eunice Kennedy Shriver National Institute of Child Health and Human Development Program (to Dolores J. Lamb).

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This article is part of the Topical Collection on Andrology and Infertility

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Deng, N., Haney, N.M., Kohn, T.P. et al. The Effect of Shift Work on Urogenital Disease: a Systematic Review. Curr Urol Rep 19, 57 (2018). https://doi.org/10.1007/s11934-018-0815-y

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