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Chronic pelvic pain syndrome and the overactive bladder: The inflammatory link

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Abstract

Although the causes of chronic prostatitis/chronic pelvic pain syndrome, painful bladder syndrome/interstitial cystitis, and overactive bladder remain unclear, inflammation may explain some of the causative and propagating features. Cytokines may play a role by recruiting inflammatory cells and ultimately in inducing symptoms. This paper reviews the role of cytokines in the pathophysiology of chronic prostatitis/chronic pelvic pain syndrome, overactive bladder, and painful bladder syndrome/interstitial cystitis.

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Correspondence to Rajiv Saini.

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Saini, R., Gonzalez, R.R. & Te, A.E. Chronic pelvic pain syndrome and the overactive bladder: The inflammatory link. Curr Urol Rep 9, 314–319 (2008). https://doi.org/10.1007/s11934-008-0054-8

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