Skip to main content
Log in

ADHD and Exposure to Maltreatment in Children and Youth: a Systematic Review of the Past 10 Years

  • Attention-Deficit Disorder (A Anthony Rostain, Section Editor)
  • Published:
Current Psychiatry Reports Aims and scope Submit manuscript

Abstract

Purpose of the Review

The purpose of the current paper was to review and summarize the literature on ADHD and maltreatment over the past 10 years.

Recent Findings

The majority of research on ADHD and exposure to maltreatment focuses on the high rates of comorbidity, including international studies from Asia, South America, North America, and Europe. Longitudinal studies showed that early exposure to maltreatment is a risk factor for ADHD symptoms later in development; however, this finding was not consistent. There were some preliminary studies on the neurological and genetic mechanisms underlying the link between ADHD and exposure to maltreatment. Finally, ADHD and exposure to maltreatment were found to have an additive effect on clinically salient outcomes (e.g., aggression, suicide attempts).

Summary

Results from the review have direct clinical and future implications, including the need to understand the effect of comorbid ADHD and exposure to maltreatment in treatment studies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Pliszka S, Issues AWGoQ. Practice parameter for the assessment and treatment of children and adolescents with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2007;46(7):894–921. https://doi.org/10.1097/chi.0b013e318054e724.

  2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: 2013.

  3. Roberts RE, Fisher PW, Turner JB, Tang M. Estimating the burden of psychiatric disorders in adolescence: the impact of subthreshold disorders. Soc Psychiatry Psychiatr Epidemiol. 2015;50(3):397–406. https://doi.org/10.1007/s00127-014-0972-3.

    Article  PubMed  Google Scholar 

  4. U. S. Preventive Services Task Force, Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, et al. Interventions to prevent child maltreatment: US Preventive Services Task Force recommendation statement. JAMA. 2018;320(20):2122–8. https://doi.org/10.1001/jama.2018.17772.

    Article  Google Scholar 

  5. Cicchetti D. Socioemotional, personality, and biological development: illustrations from a multilevel developmental psychopathology perspective on child maltreatment. Annu Rev Psychol. 2016;67:187–211. https://doi.org/10.1146/annurev-psych-122414-033259.

    Article  PubMed  Google Scholar 

  6. Van der Kolk BA. The drug treatment of post-traumatic stress disorder. J Affect Disord. 1987;13(2):203–13. https://doi.org/10.1016/0165-0327(87)90024-3.

    Article  PubMed  Google Scholar 

  7. Szymanski K, Sapanski L, Conway F. Trauma and ADHD–association or diagnostic confusion? A clinical perspective. J Infant, Child, Adolesc Psychother. 2011;10(1):51–9. https://doi.org/10.1080/15289168.2011.575704.

    Article  Google Scholar 

  8. Cohen JA, Bukstein O, Walter H, Benson SR, Chrisman A, Farchione TR, et al. Practice parameter for the assessment and treatment of children and adolescents with posttraumatic stress disorder. J Am Acad Child Adolesc Psychiatry. 2010;49(4):414–30. https://doi.org/10.1016/j.jaac.2009.12.020.

    Article  PubMed  Google Scholar 

  9. Minnis H, Green J, O’Connor TG, Liew A, Glaser D, Taylor E, et al. An exploratory study of the association between reactive attachment disorder and attachment narratives in early school-age children. J Child Psychol Psychiatry. 2009;50(8):931–42. https://doi.org/10.1111/j.1469-7610.2009.02075.x.

    Article  PubMed  Google Scholar 

  10. Dahmen B, Pütz V, Herpertz-Dahlmann B, Konrad K. Early pathogenic care and the development of ADHD-like symptoms. J Neural Transm (Vienna). 2012;119(9):1023–36. https://doi.org/10.1007/s00702-012-0809-8.

    Article  Google Scholar 

  11. Weiss MD, McBride NM, Brandt T, Esmaeilpour D, Jensen P. Symptom profiles specific to trauma in a child inpatient unit. J Am Acad Child Adolesc Psychiatry. 2019;58(8):818–20 e1. https://doi.org/10.1016/j.jaac.2019.03.024.

    Article  PubMed  Google Scholar 

  12. Weinstein D, Staffelbach D, Biaggio M. Attention-deficit hyperactivity disorder and posttraumatic stress disorder: differential diagnosis in childhood sexual abuse. Clin Psychol Rev. 2000;20(3):359–78. https://doi.org/10.1016/s0272-7358(98)00107-x.

    Article  CAS  PubMed  Google Scholar 

  13. Ford JD. Traumatic victimization in childhood and persistent problems with oppositional-defiance. J Aggress Maltreat Trauma. 2002;6(1):25–58. https://doi.org/10.1300/J146v06n01_03.

    Article  Google Scholar 

  14. Theule J, Wiener J, Rogers MA, Marton I. Predicting parenting stress in families of children with ADHD: parent and contextual factors. J Child Fam Stud. 2011;20(5):640–7. https://doi.org/10.1007/s10826-010-9439-7.

    Article  Google Scholar 

  15. Efron D, Furley K, Gulenc A, Sciberras E. Maternal ADHD symptoms, child ADHD symptoms and broader child outcomes. Arch Dis Child. 2018;103(9):841–6. https://doi.org/10.1136/archdischild-2017-313936.

    Article  PubMed  Google Scholar 

  16. Grimm O, Kranz TM, Reif A. Genetics of ADHD: what should the clinician know? Curr Psychiatry Rep. 2020;22(4):18. https://doi.org/10.1007/s11920-020-1141-x.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Chronis AM, Lahey BB, Pelham WE Jr, Kipp HL, Baumann BL, Lee SS. Psychopathology and substance abuse in parents of young children with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2003;42(12):1424–32. https://doi.org/10.1097/00004583-200312000-00009.

    Article  PubMed  Google Scholar 

  18. Williamson D, Johnston C, Noyes A, Stewart K, Weiss MD. Attention-deficit/hyperactivity disorder symptoms in mothers and fathers: family level interactions in relation to parenting. J Abnorm Child Psychol. 2017;45(3):485–500. https://doi.org/10.1007/s10802-016-0235-8.

    Article  PubMed  Google Scholar 

  19. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6(7):e1000100. https://doi.org/10.1371/journal.pmed.1000100.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Mavergames C Covidence (systematic review software). 2013.

  21. Achenbach TM. The Achenbach system of empirically based Assessemnt (ASEBA): development, findings, theory, and applications. Burlington: University of Vermont Research Center for Children, Youth, & Families; 2009.

    Google Scholar 

  22. Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME. NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J Am Acad Child Adolesc Psychiatry. 2000;39(1):28–38. https://doi.org/10.1097/00004583-200001000-00014.

    Article  CAS  PubMed  Google Scholar 

  23. Conners CK, Staff M, Connelly V, Campbell S, MacLean M, Barnes J. Conners’ continuous performance test II (CPT II v. 5). Multi-Health Syst Inc. 2000;29:175–96.

    Google Scholar 

  24. Puig-Antich J, Ryan N. Kiddie schedule for affective disorders and schizophrenia. Pittsburgh: Western Psychiatric Institute; 1986.

    Google Scholar 

  25. Bernstein DP, Stein JA, Newcomb MD, Walker E, Pogge D, Ahluvalia T, et al. Development and validation of a brief screening version of the childhood trauma questionnaire. Child Abuse Negl. 2003;27(2):169–90. https://doi.org/10.1016/s0145-2134(02)00541-0.

    Article  PubMed  Google Scholar 

  26. Bücker J, Kapczinski F, Post R, Ceresér KM, Szobot C, Yatham LN, et al. Cognitive impairment in school-aged children with early trauma. Compr Psychiatry. 2012;53(6):758–64. https://doi.org/10.1016/j.comppsych.2011.12.006.

    Article  PubMed  Google Scholar 

  27. Dinkler L, Lundström S, Gajwani R, Lichtenstein P, Gillberg C, Minnis H. Maltreatment-associated neurodevelopmental disorders: a co-twin control analysis. J Child Psychol Psychiatry. 2017;58(6):691–701. https://doi.org/10.1111/jcpp.12682.

    Article  PubMed  Google Scholar 

  28. Salum GA, DeSousa DA, Manfro GG, Pan PM, Gadelha A, Brietzke E, et al. Measuring child maltreatment using multi-informant survey data: a higher-order confirmatory factor analysis. Trends Psychiatry Psychother. 2016;38(1):23–32. https://doi.org/10.1590/2237-6089-2015-0036.

    Article  PubMed  Google Scholar 

  29. He AS, Traube DE, Brimhall KC, Lim C, Lecklitner G, Olson A. Service receipt and mental disorders in child welfare and mental health systems in Los Angeles County. Psychiatr Serv. 2017;68(8):776–82. https://doi.org/10.1176/appi.ps.201600266.

    Article  PubMed  Google Scholar 

  30. Heneghan A, Stein RE, Hurlburt MS, Zhang J, Rolls-Reutz J, Fisher E, et al. Mental health problems in teens investigated by U.S. child welfare agencies. J Adolesc Health. 2013;52(5):634–40. https://doi.org/10.1016/j.jadohealth.2012.10.269.

    Article  PubMed  Google Scholar 

  31. Kočovská E, Puckering C, Follan M, Smillie M, Gorski C, Barnes J, et al. Neurodevelopmental problems in maltreated children referred with indiscriminate friendliness. Res Dev Disabil. 2012;33(5):1560–5. https://doi.org/10.1016/j.ridd.2012.02.016.

    Article  PubMed  Google Scholar 

  32. Linares LO, Li M, Shrout PE, Ramirez-Gaite M, Hope S, Albert A, et al. The course of inattention and hyperactivity/impulsivity symptoms after foster placement. Pediatrics. 2010;125(3):e489–e98. https://doi.org/10.1542/peds.2009-1285.

    Article  PubMed  Google Scholar 

  33. Linares LO, Martinez-Martin N, Castellanos FX. Stimulant and atypical antipsychotic medications for children placed in foster homes. PLoS One. 2013;8(1):e54152-e. https://doi.org/10.1371/journal.pone.0054152.

    Article  CAS  Google Scholar 

  34. Mukherjee RAS, Cook PA, Norgate SH, Price AD. Neurodevelopmental outcomes in individuals with fetal alcohol spectrum disorder (fasd) with and without exposure to neglect: clinical cohort data from a national fasd diagnostic clinic. Alcohol. 2019;76:23–8. https://doi.org/10.1016/j.alcohol.2018.06.002.

    Article  PubMed  Google Scholar 

  35. Kambeitz C, Klug MG, Greenmyer J, Popova S, Burd L. Association of adverse childhood experiences and neurodevelopmental disorders in people with fetal alcohol spectrum disorders (FASD) and non-FASD controls. BMC Pediatr. 2019;19(1):498. https://doi.org/10.1186/s12887-019-1878-8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Ghanizadeh A, Yazdanshenas P, Nasab MM, Firoozabadi A, Farrashbandi H. Parental abuse towards their children with ADHD in Iran. J Fam Violence. 2014;29(3):269–76. https://doi.org/10.1007/s10896-014-9585-6.

    Article  Google Scholar 

  37. Hadianfard H. Child abuse in group of children with attention deficit-hyperactivity disorder in comparison with normal children. Int J Commun Based Nurs Midwifery. 2014;2(2):77–84.

    Google Scholar 

  38. Sari Gokten E, Saday Duman N, Soylu N, Uzun ME. Effects of attention-deficit/hyperactivity disorder on child abuse and neglect. Child Abuse Negl. 2016;62:1–9. https://doi.org/10.1016/j.chiabu.2016.10.007.

    Article  PubMed  Google Scholar 

  39. van Der Kolk B, Ford JD, Spinazzola J. Comorbidity of developmental trauma disorder (DTD) and post-traumatic stress disorder: findings from the DTD field trial. Eur J Psychotraumatol. 2019;10(1):1562841. https://doi.org/10.1080/20008198.2018.1562841.

    Article  Google Scholar 

  40. du Prel CX, Yi H, Liang Y, Pang K, Leeper-Woodford S, Riccardi P, et al. Family-environmental factors associated with attention deficit hyperactivity disorder in Chinese children: a case-control study. PLoS One. 2012;7(11):e50543-e. https://doi.org/10.1371/journal.pone.0050543.

    Article  CAS  Google Scholar 

  41. de la Barra FE, Vicente B, Saldivia S, Melipillan R. Epidemiology of ADHD in Chilean children and adolescents. Atten Defic Hyperact Disord. 2013;5(1):1–8. https://doi.org/10.1007/s12402-012-0090-6.

    Article  PubMed  Google Scholar 

  42. Jimenez ME, Wade R Jr, Schwartz-Soicher O, Lin Y, Reichman NE. Adverse childhood experiences and ADHD diagnosis at age 9 years in a national urban sample. Acad Pediatr. 2017;17(4):356–61. https://doi.org/10.1016/j.acap.2016.12.009.

    Article  PubMed  Google Scholar 

  43. Teixeira MC, Marino RL, Carreiro LR. Associations between inadequate parenting practices and behavioral problems in children and adolescents with attention deficit hyperactivity disorder. Sci World J. 2015;2015:683062–6. https://doi.org/10.1155/2015/683062.

    Article  Google Scholar 

  44. Mhalla A, Guedria A, Brahem T, Amamou B, Sboui W, Gaddour N, et al. ADHD in Tunisian adolescents: prevalence and associated factors. J Atten Disord. 2018;22(2):154–62. https://doi.org/10.1177/1087054717702217.

    Article  PubMed  Google Scholar 

  45. Nomura K, Okada K, Noujima Y, Kojima S, Mori Y, Amano M, et al. A clinical study of attention-deficit/hyperactivity disorder in preschool children--prevalence and differential diagnoses. Brain Dev. 2014;36(9):778–85. https://doi.org/10.1016/j.braindev.2013.11.004.

    Article  PubMed  Google Scholar 

  46. • Park S, Lee J-M, Kim J-W, Kwon H, Cho S-C, Han DH, et al. Increased white matter connectivity in traumatized children with attention deficit hyperactivity disorder. Psychiatry Res Neuroimaging. 2016;247:57–63. https://doi.org/10.1016/j.pscychresns.2015.09.012One of the only studies to look at the underlying biological mechanisms of ADHD and exposure to abuse.

  47. Kiive E, Kurrikoff T, Mäestu J, Harro J. Effect of α2a-adrenoceptor C-1291G genotype and maltreatment on hyperactivity and inattention in adolescents. Prog Neuro-Psychopharmacol Biol Psychiatry. 2010;34(1):219–24. https://doi.org/10.1016/j.pnpbp.2009.11.011.

  48. Li JJ, Lee SS. Interaction of dopamine transporter (DAT1) genotype and maltreatment for ADHD: a latent class analysis. J Child Psychol Psychiatry. 2012;53(9):997–1005. https://doi.org/10.1111/j.1469-7610.2012.02563.x.

  49. Thompson R, Tabone JK. The impact of early alleged maltreatment on behavioral trajectories. Child Abuse Negl. 2010;34(12):907–16. https://doi.org/10.1016/j.chiabu.2010.06.006.

  50. •• Cromer KD, Villodas MT. Post-traumatic stress as a pathway to psychopathology among adolescents at high-risk for victimization. Child Abuse Negl. 2017;67:182–92. https://doi.org/10.1016/j.chiabu.2017.02.025Provided evidence of the role of PTSD in mediating the effect of maltreatment on ADHD symptoms. This is critical in differential diagnosis.

  51. •• González RA, Vélez-Pastrana MC, McCrory E, Kallis C, Aguila J, Canino G, et al. Evidence of concurrent and prospective associations between early maltreatment and ADHD through childhood and adolescence. Soc Psychiatry Psychiatr Epidemiol. 2019;54(6):671–82. https://doi.org/10.1007/s00127-019-01659-0One of the few studies to look at prospective longitudinal evidence that exposure to maltreatment increased risk for later ADHD symptoms.

  52. Stern A, Agnew-Blais J, Danese A, Fisher HL, Jaffee SR, Matthews T, et al. Associations between abuse/neglect and ADHD from childhood to young adulthood: a prospective nationally-representative twin study. Child Abuse Negl. 2018;81:274–85. https://doi.org/10.1016/j.chiabu.2018.04.025.

  53. Calhoun BH, Ridenour TA, Fishbein DH. Associations between child maltreatment, harsh parenting, and sleep with adolescent mental health. J Child Fam Stud. 2019;28(1):116–30. https://doi.org/10.1007/s10826-018-1261-7.

  54. Guendelman MD, Owens EB, Galán C, Gard A, Hinshaw SP. Early-adult correlates of maltreatment in girls with attention-deficit/hyperactivity disorder: increased risk for internalizing symptoms and suicidality. Dev Psychopathol. 2016;28(1):1–14. https://doi.org/10.1017/S0954579414001485.

  55. Gul H, Gurkan CK. Child maltreatment and associated parental factors among children with ADHD: a comparative study. J Atten Disord. 2018;22(13):1278–88. https://doi.org/10.1177/1087054716658123.

    Article  PubMed  Google Scholar 

  56. Evinç ŞG, Gençöz T, Foto-Özdemir D, Akdemir D, Karadağ F, Ünal F. Child maltreatment and associated factors among children with ADHD: a comparative study. Turk J Pediatr. 2014;56(1):11–22.

    PubMed  Google Scholar 

  57. Ma JLC, Lai K, Wan ESF. Maltreatment in parent–child relationships of Chinese families with children suffering from attention deficit hyperactivity disorder in Hong Kong: a qualitative study. Br J Soc Work. 2016;46(7):2051–69. https://doi.org/10.1093/bjsw/bcv079.

    Article  Google Scholar 

  58. Zou S, Yu W, Liang S, Ma X, Li D, Bian Y, et al. The association between child abuse and emotional and behavioral problems in Chinese school-aged boys with attention deficit hyperactivity disorder. J Nerv Ment Dis. 2019;207(10):869–74. https://doi.org/10.1097/NMD.0000000000001041.

    Article  PubMed  Google Scholar 

  59. De Sanctis VA, Nomura Y, Newcorn JH, Halperin JM. Childhood maltreatment and conduct disorder: independent predictors of criminal outcomes in ADHD youth. Child Abuse Negl. 2012;36(11–12):782–9. https://doi.org/10.1016/j.chiabu.2012.08.003.

    Article  PubMed  PubMed Central  Google Scholar 

  60. Tidefors I, Strand J. Life history interviews with 11 boys diagnosed with attention-deficit/hyperactivity disorder who had sexually offended: a sad storyline. J Trauma Dissociation. 2012;13(4):421–34. https://doi.org/10.1080/15299732.2011.652344.

    Article  PubMed  Google Scholar 

  61. Conway F, Oster M, Szymanski K. ADHD and complex trauma: a descriptive study of hospitalized children in an urban psychiatric hospital. J Infant, Child, Adolesc Psychother. 2011;10(1):60–72. https://doi.org/10.1080/15289168.2011.575707.

    Article  Google Scholar 

  62. Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: the adverse childhood experiences (ACE) study. Am J Prev Med. 1998;14(4):245–58. https://doi.org/10.1016/s0749-3797(98)00017-8.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Stephanie G. Craig.

Ethics declarations

Conflict of Interest

Stephanie G. Craig, Bianca C. Bondi, Katherine A. O’Donnell, and Debra J. Pepler declare that they have no conflicts of interest. Dr. Margaret D. Weiss reports non-financial support from Purdue Pharma CA, personal fees and non-financial support from Takeda, personal fees from Tris, personal fees and non-financial support from Global Medical Education, personal fees from Huron Consulting, personal fees and non-financial support from Rhodes, personal fees and non-financial support from MHS, personal fees from Mundipharma, personal fees from Johns Hopkins University Press, personal fees and non-financial support from MHS, non-financial support from Eunethydis, non-financial support from World Federation of ADHD, non-financial support from Israeli Foundation for ADHD, non-financial support from Canadian Attention Deficit Resource Alliance, non-financial support from American Professional Association for ADHD, non-financial support from Purdue Pharma US, personal fees and non-financial support from Cingulate, non-financial support from Children and Adults with ADD, personal fees from Boston Children’s Hospital, personal fees from Tris, outside the submitted work.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical collection on Attention-Deficit Disorder

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Craig, S.G., Bondi, B.C., O’Donnell, K.A. et al. ADHD and Exposure to Maltreatment in Children and Youth: a Systematic Review of the Past 10 Years. Curr Psychiatry Rep 22, 79 (2020). https://doi.org/10.1007/s11920-020-01193-w

Download citation

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s11920-020-01193-w

Keywords

Navigation