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Neuroinflammation and Schizophrenia

  • Schizophrenia and Other Psychotic Disorders (AK Pandurangi, Section Editor)
  • Published:
Current Psychiatry Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

There are longstanding, intriguing findings of immune dysfunction in schizophrenia. These findings span peripheral immune markers, especially cytokine abnormalities.

Recent Findings

This review describes recent genetic and immune marker studies and emergent treatment studies.

Summary

Collectively, this provides a synthesis and current appraisal of the neuroimmune hypothesis of schizophrenia.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Virginia Commonwealth University School of Medicine, 1201 East Marshall St., 4th floor, Richmond, VA, 23298, USA

    Peter F. Buckley

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  1. Peter F. Buckley
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Correspondence to Peter F. Buckley.

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Conflict of Interest

Peter F. Buckley is a co-investigator on research grants supporting the study of immunologic drugs for schizophrenia for the Stanley Foundation and the Brain & Behavior Research Foundation.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Schizophrenia and Other Psychotic Disorders

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Buckley, P.F. Neuroinflammation and Schizophrenia. Curr Psychiatry Rep 21, 72 (2019). https://doi.org/10.1007/s11920-019-1050-z

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