Skip to main content

Advertisement

Log in

The genetics of antisocial behavior

  • Published:
Current Psychiatry Reports Aims and scope Submit manuscript

Abstract

Overall, the evidence from over 100 twin and adoption studies of antisocial behavior suggests that genetic factors account for about half of the variation in risk. However, behavioral genetic studies of antisocial behavior still tend to produce far-ranging estimates of heritability, suggesting that there may be important moderators of these genetic risk factors. In this review, the results of some recent behavioral genetic studies of antisocial behavior that focus on the following issues are examined: 1) developmental changes in the heritability of antisocial behaviors, 2) developmental subtypes of antisocial behavior disorders, 3) sex differences in the heritability of antisocial behavior, 4) cohort differences in the heritability of antisocial behavior, and 5) the genetics of antisocial behavior comorbidity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References and Recommended Reading

  1. Rhee SH, Waldman ID: Genetic and environmental influences on antisocial behavior: a meta-analysis of twin and adoption studies. Psychol Bull 2001, in press. The authors conduct a careful quantitative synthesis of 51 twin and adoption studies of antisocial behavior, and examine the effect of several moderator variables including sex, age, definition of antisocial behavior used, and study design.

  2. Kendler KS: Overview: a current perspective on twin studies of schizophrenia. Am J Psychiatry 1983, 140:1413–1425.

    PubMed  CAS  Google Scholar 

  3. Sullivan PF, Neale MC, Kendler, KS: The genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry 2000, 157:1552–1562.

    Article  PubMed  CAS  Google Scholar 

  4. Waldman ID, Slutske WS: Antisocial behavior and alcoholism: a behavioral genetic perspective on comorbidity. Clin Psychol Rev 2000, 20:255–287.

    Article  PubMed  CAS  Google Scholar 

  5. Thapar A, Holmes J, Poulton K, Harrington R: Genetic basis of attention deficit and hyperactivity. Br J Psychiatry 1999, 174:105–111.

    PubMed  CAS  Google Scholar 

  6. Cloninger CR, Gottesman II: Genetic and environmental factors in antisocial behavior disorders. In The Causes of Crime: New Biological Approaches. Edited by Mednick SA, Moffitt TE, Stack SA. Cambridge: Cambridge University Press; 1987:92–109.

    Google Scholar 

  7. Lyons MJ, True W, Eisen S, et al.: Differential heritability of adult and juvenile antisocial traits. Arch Gen Psychiatry 1995, 52:906–915.

    PubMed  CAS  Google Scholar 

  8. Jacobson KC, Prescott CA, Kendler KS: Sex differences in the genetic and environmental influences on the development of antisocial behavior. Dev Psychopathol 2001, in preparation.

  9. Lyons MJ: A twin study of self-reported criminal behavior. In Genetics of Criminal and Antisocial Behavior. Edited by Bock GR, Goode JA. Chichester: John Wiley & Sons; 1996:61–86.

    Google Scholar 

  10. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, edn 4: DSM-IV. Washington, DC: American Psychiatric Association; 1994.

    Google Scholar 

  11. Lahey BB, Loeber R, Quay HC, et al.: Oppositional defiant disorder and conduct disorder. In DSM-IV Sourcebook, vol 3. Edited by Widiger TA, Frances AJ, Pincus HA, et al.: Washington, DC: American Psychiatric Association; 1997:189–209.

    Google Scholar 

  12. Hinshaw SP: Conduct disorder in childhood: conceptualization, diagnosis, comorbidity, and risk status for antisocial functioning in adulthood. In Progress in Experimental Personality & Psychopathology Research. Edited by Fowles DC, Sutker P, Goodman SH. New York: Springer; 1994:3–44.

    Google Scholar 

  13. Moffitt TE, Caspi A, Dickson N, et al.: Childhood-onset versus adolescent-onset antisocial conduct problems in males: natural history from ages 3 to 18 years. Dev Psychopathol 1996, 8:399–424.

    Article  Google Scholar 

  14. Loeber R: Natural histories of conduct problems, delinquency, and associated substance use: evidence for developmental progressions. Adv Clin Child Psychol 1988, 11:73–124.

    Google Scholar 

  15. Moffitt TE: Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychol Rev 1993, 100:674–701.

    Article  PubMed  CAS  Google Scholar 

  16. DiLalla LF, Gottesman II: Heterogeneity of causes for delinquency and criminality: lifespan perspectives. Dev Psychopathol 1989, 1:339–349.

    Google Scholar 

  17. Slutske WS, Lyons MJ, True WR, et al.: Testing a developmental taxonomy of antisocial behavior. In Paper presented at the Behavior Genetics Association meeting. Toronto, Canada: July 10–13, 1997.

  18. Miles DR, Carey G: Genetic and environmental architecture of human aggression. J Personal Soc Psychol 1997, 72:207–217. A quantitative synthesis of 24 twin and adoption studies of aggression.

    Article  CAS  Google Scholar 

  19. Slutske WS, Heath AC, Dinwiddie SH, et al.: Modeling genetic and environmental influences in the etiology of conduct disorder: a study of 2682 adult twin pairs. J Abnorm Psychol 1997, 106:266–279.

    Article  PubMed  CAS  Google Scholar 

  20. Cloninger CR, Christiansen KO, Reich T, Gottesman II: Implications of sex differences in the prevalences of antisocial personality, alcoholism, and criminality for familial transmission. Arch Gen Psychiatry 1978, 35:941–951.

    PubMed  CAS  Google Scholar 

  21. Jacobson KC, Prescott CA, Neale MC, Kendler KS: Cohort differences in genetic and environmental influences on retrospective reports of conduct disorder among male adult twins. Psychol Med 2000, 30:775–787.

    Article  PubMed  CAS  Google Scholar 

  22. Silberg J, Rutter M, Meyer J, et al.: Genetic and environmental influences on the covariation between hyperactivity and conduct disturbance in juvenile twins. J Child Psychol Psychiatry 1996, 37:803–816.

    Article  PubMed  CAS  Google Scholar 

  23. Slutske WS, Heath AC, Dinwiddie SH, et al.: Common genetic risk factors for conduct disorder and alcohol dependence. J Abnorm Psychol 1998, 107:363–374.

    Article  PubMed  CAS  Google Scholar 

  24. Jang KL, Vernon PA, Livesley WJ: Personality disorder traits, family environment, and alcohol misuse: a multivariate behavioural genetic analysis. Addiction 2000, 95:873–888.

    Article  PubMed  CAS  Google Scholar 

  25. Slutske WS, Eisen SA, Xian H, et al.: A twin study of the association between pathological gambling and antisocial personality disorder. J Abnorm Psychol 2001, in press.

  26. Young SE, Stallings MC, Corley RP, et al.: Genetic and environmental influences on behavioral disinhibition. Am J Med Genet (Neuropsychiatr Genet) 2000, 96:684–695. Using multivariate behavioral genetic statistical techniques, the authors identify a highly heritable latent trait of behavioral disinhibition that may be useful as a phenotype in molecular genetic studies.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Slutske, W.S. The genetics of antisocial behavior. Curr Psychiatry Rep 3, 158–162 (2001). https://doi.org/10.1007/s11920-001-0014-1

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11920-001-0014-1

Keywords

Navigation