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Chronic Pain Following Concussion

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References

  1. Kraus JF, McArthur DL. Epidemiologic aspects of brain injury. Neurol Clin. 1996;14(2):435.

    Article  CAS  PubMed  Google Scholar 

  2. Practice parameter: the management of concussion in sports (summary statement). Report of the Quality Standards Subcommittee. Neurology. 1997;48(3):581–5.

  3. McCrory P, Meeuwisse WH, Aubry M, Cantu B, Dvorák J, Echemendia RJ, et al. Consensus statement on concussion in sport: the 4th International Conference on Concussion in Sport held in Zurich, November 2012. Br J Sports Med. 2013;47(5):250–8.

  4. Shultz SR, McDonald SJ, Haar CV, Meconi A, Vink R, van Donkelaar P, et al. The potential for animal models to provide insight into mild traumatic brain injury: translational challenges and strategies. Neurosci Biobehav Rev. 2016. doi:10.1016/j.neubiorev.2016.09.014.

    Google Scholar 

  5. Lucas S. Posttraumatic headache: clinical characterization andmanagement. Curr Pain Headache Rep. 2015;19(10):48.

    Article  PubMed  Google Scholar 

  6. Nampiaparampil DE. Prevalence of chronic pain after traumatic brain injury: a systematic review. JAMA. 2008;300(6):711–9. doi:10.1001/jama.300.6.711.

    Article  CAS  PubMed  Google Scholar 

  7. Wilk JE, Thomas JL, McGurk DM, Riviere LA, Castro CA, Hoge CW. Mild traumatic brain injury (concussion) during combat: lack of association of blast mechanism with persistent postconcussive symptoms. J Head Trauma Rehabil. 2010;25(1):9–14. doi:10.1097/HTR.0b013e3181bd090f.

    Article  PubMed  Google Scholar 

  8. Gironda RJ, Clark ME, Ruff RL, Chait S, Craine M, Walker R, et al. Traumatic brain injury, polytrauma, and pain: challenges and treatment strategies for the polytrauma rehabilitation. Rehabil Psychol. 2009;54(3):247–58. doi:10.1037/a0016906.

    Article  PubMed  Google Scholar 

  9. Lew HL, Otis JD, Tun C, Kerns RD, Clark ME, Cifu DX. Prevalence of chronic pain, posttraumatic stress disorder, and persistent postconcussive symptoms in OIF/OEF veterans: polytrauma clinical triad. J Rehabil Res Dev. 2009;46(6):697–702.

    Article  PubMed  Google Scholar 

  10. Ofek H, Defrin R. The characteristics of chronic central pain after traumatic brain injury. Pain. 2007;131(3):330–40.

    Article  PubMed  Google Scholar 

  11. Conidi FX. Interventional treatment for post-traumatic headache. Curr Pain Headache Rep. 2016;20(6):40. doi:10.1007/s11916-016-0570-z.

    Article  PubMed  Google Scholar 

  12. Ruff RL, Blake K. Pathophysiological links between traumatic brain injury and post-traumatic headaches. 2016;5. doi:10.12688/f1000research.9017.1.

  13. MacDonald CL, Johnson AM, Nelson EC, Werner NJ, Fang R, Flaherty SF, et al. Functional status after blast-plus impact complex concussive traumatic brain injury in evacuated United States military personnel. J Neurotrauma. 2014;31(10):889–98.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Baandrup L, Jensen R. Chronic post-traumatic headache—a clinical analysis in relation to the International Headache Classification 2nd Edition. Cephalalgia. 2005;25(2):132.

    Article  CAS  PubMed  Google Scholar 

  15. Haas DC. Chronic post-traumatic headaches classified and compared with natural headaches. Cephalalgia. 1996;16(7):486.

    Article  CAS  PubMed  Google Scholar 

  16. Couch JR, Bearss C. Chronic daily headache in the posttrauma syndrome: relation to extent of head injury. Headache. 2001;41(6):559.

    Article  CAS  PubMed  Google Scholar 

  17. The International Classification of Headache Disorders, 3rd edition (beta version).Headache Classification Committee of the International Headache Society (IHS): Cephalalgia. 2013;33(9):629–808.

  18. Vargas BB. Posttraumatic headache in combat soldiers and civilians: what factors influence the expression of tension-type versus migraine headache? Curr Pain Headache Rep. 2009;13(6):470.

    Article  PubMed  Google Scholar 

  19. Riechers 2nd RG, Walker MF, Ruff RL. Post-traumatic headaches. Handb Clin Neurol. 2015;128:567–78. doi:10.1016/B978-0-444-63521-1.00036-4.

    Article  PubMed  Google Scholar 

  20. Kapur N, Kamel IR, Herlich A. Oral and craniofacial pain: diagnosis, pathophysiology, and treatment. Int Anesthesiol Clin. 2003;41(3):115–50.

    Article  PubMed  Google Scholar 

  21. Facial pain and the neuralgias. In: Handbook of headache management: A practical guide to diagnosis and treatment of head, neck, and facial pain. Saper, JR, Silberstein, S, Gordon, CD, et al. (Eds), Lippincott Williams and Wilkins, Baltimore, Maryland 1999. p.249.

  22. Deda G, Caksen H, Ocal A. Headache etiology in children: a retrospective study of 125 cases. Pediatr Int. 2000;42(6):668–73.

    Article  CAS  PubMed  Google Scholar 

  23. Silberstein SD, Marcelis J. Headache associated with changes in intracranial pressure. Headache. 1992;32(2):84.

    Article  CAS  PubMed  Google Scholar 

  24. Evans RW. Posttraumatic headaches in civilians, soldiers, and athletes. Neurol Clin. 2014;32(2):283–303. doi:10.1016/j.ncl.2013.11.010.

    Article  PubMed  Google Scholar 

  25. Gorelick PB, Hier DB, Caplan LR, Langenberg P. Headache in acute cerebrovascular disease. Neurology. 1986;36(11):1445.

    Article  CAS  PubMed  Google Scholar 

  26. Stanbro M, Gray BH, Kellicut DC. Carotidynia: revisiting an unfamiliar entity. Ann Vasc Surg. 2011;25(8):1144–53.

    Article  PubMed  Google Scholar 

  27. Finkel AG. Epidemiology of cluster headache. Curr Pain Headache Rep. 2003;7(2):144.

    Article  PubMed  Google Scholar 

  28. Lay CL, Newman LC. Posttraumatic hemicrania continua. Headache. 1999;39(4):275.

    Article  CAS  PubMed  Google Scholar 

  29. Putzki N, Nirkko A, Diener HC. Trigeminal autonomic cephalalgias: a case of post-traumatic SUNCT syndrome? Cephalalgia. 2005;25(5):395.

    Article  CAS  PubMed  Google Scholar 

  30. Kim JH, Ahn SH, Cho YW, Kim SH, Jang SH. The relation between injury of the spinothalamocortical tract and central pain in chronic patients with mild traumatic brain injury. J Head Trauma Rehab 30(6):E40–E46. doi: 10.1097/HTR.0000000000000121.

  31. Feliciano DP, Sahbaie P, Shi X, Klukinov M, Clark JD, Yeomans DC. Nociceptive sensitization and BDNF up-regulation in a rat model of traumatic brain injury. Neurosci Lett. 2014;583:55–9. doi:10.1016/j.neulet.2014.09.030.

    Article  CAS  PubMed  Google Scholar 

  32. Belanger HG, Curtiss G, Demery JA, Lebowitz BK, Vanderploeg RD. Factors moderating neuropsychological outcomes following mild traumatic brain injury: a meta-analysis. J Int Neuropsychol Soc. 2005;11(3):215.

    Article  PubMed  Google Scholar 

  33. Schretlen DJ, Shapiro AM. A quantitative review of the effects of traumatic brain injury on cognitive functioning. Int Rev Psychiatry. 2003;15(4):341.

    Article  PubMed  Google Scholar 

  34. Hesselink JR, Dowd CF, Healy ME, Hajek P, Baker LL, Luerssen TG. MR imaging of brain contusions: a comparative study with CT. AJR Am J Roentgenol. 1988;150(5):1133.

    Article  CAS  PubMed  Google Scholar 

  35. Patterson ZR, Holahan MR. Understanding the neuroinflammatory response following concussion to develop treatment strategies. Front Cell Neurosci. 2012;6:58. doi:10.3389/fncel.2012.00058. eCollection 2012.

  36. Mayer CL, Huber BR, Peskind E. Traumatic brain injury, neuroinflammation, and post-traumatic headaches. Headache. 2013;53(9):1523–30. doi:10.1111/head.12173.

    PubMed  PubMed Central  Google Scholar 

  37. Yi JH, Hazell AS. Excitotoxic mechanisms and the role of astrocytic glutamate transporters in traumatic brain injury. Neurochem Int. 2006;48(5):394–403.

    Article  CAS  PubMed  Google Scholar 

  38. Leung A, Shukla S, Yang E, Canlas B, Kadokana M, Heald J, Davani A, Song D, Lin L, Polston G, Tsai A, Lee R. Diminished supraspinal pain modulation in patients with mild traumatic brain injury. Mol Pain. 2016;12. doi: 10.1177/1744806916662661. Print 2016.

  39. Defrin R, Gruener H, Schreiber S, Pick CG. Quantitative somatosensory testing of subjects with chronic post-traumatic headache: implication on its mechanisms. Eur J Pain. 2010;14:924–31.

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Authors and Affiliations

  1. Translational Pain Research, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA

    Christine N. Sang & Lalitha Sundararaman

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  1. Christine N. Sang
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  2. Lalitha Sundararaman
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Correspondence to Christine N. Sang.

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Christine N. Sang and Lalitha Sundararaman declare that they have no conflicts of interest relevant to this paper.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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Sang, C.N., Sundararaman, L. Chronic Pain Following Concussion. Curr Pain Headache Rep 21, 1 (2017). https://doi.org/10.1007/s11916-016-0601-9

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