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New Daily Persistent Headache: An Update

  • Uncommon Headache Syndromes (J Ailani, Section Editor)
  • Published:
Current Pain and Headache Reports Aims and scope Submit manuscript

Abstract

New daily persistent headache is a primary headache disorder marked by a unique temporal profile which is daily from onset. For many sufferers this is their first ever headache. Very little is known about the pathogenesis of this condition. It might be a disorder of abnormal glial activation with persistent central nervous system inflammation and it may be a syndrome that occurs in individuals who have a history of cervical hypermobility. At present there is no known specific treatment and many patients go for years to decades without any improvement in their condition despite aggressive therapy. This article will present an up-to-date overview of new daily persistent headache on the topics of clinical presentation, treatment, diagnostic criteria, and presumed pathogenesis. It will also provide some of the authors own treatment suggestions based on recognized triggering events and some suggestions for future clinical trials.

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References

Papers of particular interest, published recently, have been highlighted as:•• Of major importance

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Conflict of Interest

Todd Rozen declares that he has no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Department of Neurology, Geisinger Health System- Geisinger Wyoming Valley, MC 37-31, 1000 E. Mountain Drive, Wilkes-Barre, PA, 18711, USA

    Todd D. Rozen

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  1. Todd D. Rozen
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Correspondence to Todd D. Rozen.

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This article is part of the Topical Collection on Uncommon Headache Syndromes

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Rozen, T.D. New Daily Persistent Headache: An Update. Curr Pain Headache Rep 18, 431 (2014). https://doi.org/10.1007/s11916-014-0431-6

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  • DOI: https://doi.org/10.1007/s11916-014-0431-6

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