Skip to main content

Advertisement

Log in

Why HURT? A Review of Clinical Instruments for Headache Management

  • Migraine Headache (F Taylor, Section Editor)
  • Published:
Current Pain and Headache Reports Aims and scope Submit manuscript

Abstract

The Global Campaign against Headache, directed by the non-governmental organization Lifting The Burden (LTB) in official relations with the World Health Organization (WHO), aspires to reduce the global burden of headache. Ultimately this calls for improvements in headache management, largely in primary care, where most people with headache receive medical care. In support, LTB is developing a range of headache management aids for primary care. Presently, no single instrument covers the range of assessment and decision-making necessary for successful headache management, and few make the important link between assessment and clinical advice. Expressly to fill this gap, LTB has developed a new instrument: the Headache Under-Response to Treatment (HURT) Questionnaire, an eight-item, self-administered questionnaire addressing headache frequency, disability, medication use and effect, perceptions of headache “control” and knowledge of diagnosis. This instrument is intended not only to evaluate current headache outcomes and assess the need for and response to treatment, but also to provide guidance on appropriate actions towards treatment optimization. The first draft of the HURT was created by an expert consensus group, meeting at WHO headquarters in Geneva, Switzerland. The final version came about through multiple refinements following psychometric testing. Assessment of clinical utility is ongoing in multiple countries.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: •Of importance ••Of major importance

  1. Stovner LJ, Hagen K, Jensen R, et al. The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia. 2007;27:193–210.

    Article  PubMed  Google Scholar 

  2. •• World Health Organization and Lifting The Burden: Atlas of headache disorders and resources in the world. Geneva, WHO; 2011. The Atlas of Headache Disorders presents data on prevalence, burden, treatment, costs, education, and unmet needs in headache worldwide acquired through in a questionnaire survey of neurologists, general practitioners and patients’ representatives from 101 countries, performed from October 2006 until March 2009. Additional relevant data from epidemiological studies were compiled through a systematic review and supplemented by data gathered in population-based studies undertaken within the global campaign.

  3. Silberstein SD, Olesen J, Bousser M-G, et al. The international classification of headache disorders: 2nd Edition. Cephalalgia. 2004;24 suppl 1:1–160.

    Google Scholar 

  4. Lifting The Burden: The Global Campaign against Headache. HURT (Headache Under-Response to Treatment) Index (v 2.2). Available at http://www.l-t-b.org./assets/96/AB9C64EE-D800-01AB-1FAC446E25B0DF88_document/HURT_NY_revision.pdf. Accessed March 2012.

  5. Steiner TJ. World Headache Alliance: lifting the burden: the global campaign against headache. Lancet Neurol. 2004;3:204–5.

    Article  PubMed  CAS  Google Scholar 

  6. Steiner TJ. Lifting The Burden: the global campaign to reduce the burden of headache worldwide. J Headache Pain. 2005;6:373–7.

    Article  PubMed  Google Scholar 

  7. • Steiner TJ, Birbeck GL, Jensen R, et al. Lifting the Burden: the first 7 years. J Headache Pain. 2010;11:451–5. This article describes the history, conception, guiding principles, goals, and accomplishments of the Lifting the Burden Campaign from 2003 to 2010 as well as works in progress and future plans..

    Article  PubMed  Google Scholar 

  8. Lipton RB, Bigal ME, Amatniek JC, Stewart WF. Tools for diagnosing migraine and measuring its severity. Headache. 2004;44:387–98.

    Article  PubMed  Google Scholar 

  9. Steiner TJ. National and international action plans for improving headache diagnosis. In: Olesen J, editor. Classification and diagnosis of headache disorders. Oxford: Oxford University Press; 2004. p. 265–71.

    Google Scholar 

  10. Frishberg BM, Rosenberg JH, Matchar DB, et al., for the U.S. Headache Consortium. Evidence-based guidelines in the primary care setting: neuroimaging in patients with nonacute headache. Available at http://www.aan.com/professionals/practice/guideline/index.cfm. Accessed February 2012.

  11. Matchar DB, Young WB, Rosenberg JH et al. Multispecialty consensus on diagnosis and treatment of headache: pharmacological management of acute attacks. Available at http://www.aan.com/professionals/practice/guideline/index.cfm. Accessed February 2012.

  12. Steiner TJ, Paemeleire K, Jensen R, et al. European principles of management of common headache disorders in primary care. J Headache Pain. 2007;8:S3–47.

    Article  PubMed  Google Scholar 

  13. Dodick DW. Clinical clues and clinical rules: primary versus secondary headache. Adv Stud Med. 2003;3:S550–5.

    Google Scholar 

  14. Maizels M, Houle T. Results of screening with the brief headache screen compared with a modified ID Migraine. Headache. 2008;48:385–94.

    Article  PubMed  Google Scholar 

  15. Lipton RB, Dodick D, Sadovsky R, et al. A self-administered screener for migraine in primary care: the ID Migraine validation study. Neurology. 2003;61:375–82.

    PubMed  CAS  Google Scholar 

  16. Maizels M, Wolfe WJ. An expert system for headache diagnosis: the Computerized Headache Assessment tool (CHAT). Headache. 2008;48:72–8.

    Article  PubMed  Google Scholar 

  17. • Jensen R, Tassorelli C, Rossi P, et al. A basic diagnostic headache diary (BDHD) is well accepted and useful in the diagnosis of headache: a multicentre European and Latin American study. Cephalalgia. 2011;31:1549–60. Researchers investigated the BDHD at headache centers throughout Europe and Latin America. When used in conjunction with clinical interview, the BDHD provides health care professionals with information complete for diagnosis significantly more frequently than interview alone..

    Article  PubMed  CAS  Google Scholar 

  18. Lipton RB, Bigal ME, Ashina S, et al. Cutaneous allodynia in the migraine population. Ann Neurol. 2008;63:148–58.

    Article  PubMed  Google Scholar 

  19. Andrasik F. Migraine and quality of life: psychological considerations. J Headache Pain. 2001;2:S1–9.

    Article  Google Scholar 

  20. Andrasik F. Psychophysiological disorders: headache as a case in point. In: Andrasik F, editor. Comprehensive handbook of personality and psychopathology, volume two: adult psychopathology. Hoboken: Wiley; 2006. p. 409–22.

    Google Scholar 

  21. • Buse DC, Rupnow MF, Lipton RB. Assessing and managing all aspects of migraine: migraine attacks, migraine-related functional impairment, common comorbidities, and quality of life. Mayo Clin Proc. 2009;84:422–35. This article reviews multiple domains of assessment necessary for comprehensive headache care. It introduces and describes the development and psychometric data for the MPQ-5 and MIBS-4 and reviews empirical and guidelines supported pharmacologic and nonpharmacologic approaches to migraine management. Also, several strategies are recommended to improve office visit communication with the intention of improving migraine impact assessment and treatment planning..

    PubMed  Google Scholar 

  22. Leonardi M, Steiner TJ, Scher AT, Lipton RB. The global burden of migraine: measuring disability in headache disorders with WHO’s Classification of Functioning, Disability, and Health (ICF). J Headache Pain. 2005;6:429–40.

    Article  PubMed  Google Scholar 

  23. Bussone G, Usai S, Grazzi L, et al. Disability and quality of life in different primary headaches: results from Italian studies. Neurol Sci. 2004;25:S105–7.

    Article  PubMed  Google Scholar 

  24. Solomon GD, Skobieranda FG, Gragg LA. Quality of life and well-being of headache patients: measurement by the medical outcomes study instrument. Headache. 1993;33:351–8.

    Article  PubMed  CAS  Google Scholar 

  25. Bigal ME, Rapoport AM, Lipton RB, et al. Assessment of migraine disability using the Migraine Disability Assessment (MIDAS) questionnaire: a comparison of chronic migraine with episodic migraine. Headache. 2003;43:336–42.

    Article  PubMed  Google Scholar 

  26. Bigal ME, Serrano D, Reed M, Lipton RB. Chronic migraine in the population: burden, diagnosis, and satisfaction with treatment. Neurology. 2008;71:559–66.

    Article  PubMed  Google Scholar 

  27. Buse DC, Manack A, Serrano D, et al. Sociodemographic and comorbidity profiles of chronic migraine and episodic migraine sufferers. J Neurol Neurosurg Psychiatry. 2010;81:428–32.

    Article  PubMed  CAS  Google Scholar 

  28. Lipton RB, Liberman JN, Kolodner KB, et al. Migraine headache disability and health-related quality-of-life: a population-based case–control study from England. Cephalalgia. 2003;23:441–50.

    Article  PubMed  CAS  Google Scholar 

  29. Ware Jr JE, Kosinski M, Keller SD. A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34:220–33.

    Article  PubMed  Google Scholar 

  30. Ware Jr JE, Sherbourne CD. The MOS 36-item short-form survey (SF-36): I. Conceptual framework and item selection. Med Care. 1996;30:473–83.

    Article  Google Scholar 

  31. Solomon GD. Evolution of the measurement of quality of life in migraine. Neurology. 1997;48:S10–5.

    PubMed  CAS  Google Scholar 

  32. Martin BC, Pathak DS, Sharfman MI, et al. Validity and reliability of the migraine-specific quality of life questionnaire (MSQ Version 2.1). Headache. 2000;40:204–15.

    Article  PubMed  CAS  Google Scholar 

  33. Wagner TH, Patrick DL, Galer BS, Berzon RA. A new instrument to assess the long term quality of life effects from migraine: development and psychometric testing of the MSQOL. Headache. 1996;36:484–92.

    Article  PubMed  CAS  Google Scholar 

  34. El Hasnaoui A, Vray M, Richard A, MIGSEV Group, et al. Assessing the severity of migraine: development of the MIGSEV scale. Headache. 2003;43:628–35.

    Article  PubMed  Google Scholar 

  35. Stewart WF, Lipton RB, Simon D, et al. Reliability of an illness severity measure for headache in a population sample of migraine sufferers. Cephalalgia. 1998;18:44–51.

    Article  PubMed  CAS  Google Scholar 

  36. Blumenfeld AM, Varon SF, Wilcox TK, et al. Disability, HRQoL and resource use among chronic and episodic migraineurs: results from the International Burden of Migraine Study (IBMS). Cephalalgia. 2011;31:301–15.

    Article  PubMed  CAS  Google Scholar 

  37. Stewart WF, Lipton RB, Kolodner KB, et al. Validity of the Migraine Disability Assessment (MIDAS) score in comparison to a diary-based measure in a population sample of migraine sufferers. Pain. 2000;88:41–52.

    Article  PubMed  CAS  Google Scholar 

  38. Hershey AD, Powers SW, Vockell ALB, et al. Development of a questionnaire to assess disability of migraines in children. Neurology. 2001;57:2034–9.

    PubMed  CAS  Google Scholar 

  39. Steiner TJ. The HALT and HART indices. J Headache Pain. 2007;8:S22–5.

    Google Scholar 

  40. Kosinski M, Bayliss MS, Bjorner JB, et al. A six-item short-form survey for measuring headache impact: the HIT-6. Qual Life Res. 2003;12:963–74.

    Article  PubMed  CAS  Google Scholar 

  41. Pathak DS, Chisolm DJ, Weis KA. Functional Assessment in Migraine (FAIM) questionnaire: development of an instrument based upon the WHO’s International Classification of Functioning, Disability, and Health. Value Health. 2005;8:591–600.

    Article  PubMed  Google Scholar 

  42. Cramer JA, Silberstein SD, Winner P. Development and validation of the Headache Needs Assessment (HANA) survey. Headache. 2001;41:402–9.

    Article  PubMed  CAS  Google Scholar 

  43. Dahlof CGH, Dimenäs E. Migraine patients experience poorer subjective well-being/quality of life even between attacks. Cephalalgia. 1995;15:31–6.

    Article  PubMed  CAS  Google Scholar 

  44. Jacobson GP, Ramadan NM, Aggarwal SK, Newman CK. The Henry ford Hospital Disability Inventory (HDI). Neurology. 1994;44:837–42.

    PubMed  CAS  Google Scholar 

  45. Jacobson GP, Ramadan NM, Norris L, Newman CW. Headache disability inventory (HDI): short-term test-retest reliability and spouse perceptions. Headache. 1995;35:534–9.

    Article  PubMed  CAS  Google Scholar 

  46. Buse DC, Bigal ME, Rupnow MFT, et al. The Migraine Interictal Burden Scale (MIBS): results of a population-based validation study. Headache. 2007;47:778.

    Google Scholar 

  47. Scher AI, Bigal ME, Lipton RB. Comorbidity of migraine. Curr Opin Neurol. 2005;18:305–10.

    Article  PubMed  Google Scholar 

  48. Breslau N, Davis GC, Andreski P. Migraine, psychiatric disorders, and suicide attempts: an epidemiologic study of young adults. Psychiatry Res. 1991;37:11–23.

    Article  PubMed  CAS  Google Scholar 

  49. Blanchard EB, Andrasik F, Evans DD, et al. Behavioral treatment of 250 chronic headache patients: a clinical replication series. Behav Ther. 1985;16:308–27.

    Article  Google Scholar 

  50. Jacob RG, Turner SM, Szekely BC, Eidelman BH. Predicting outcome of relaxation therapy in headaches: the role of “depression.”. Behav Ther. 1983;14:457–65.

    Article  Google Scholar 

  51. Holroyd KA, Holm JE, Hursey KG, et al. Recurrent vascular headache: home-based behavioral treatment vs. abortive pharmacological treatment. J Consult Clin Psychol. 1988;56:218–23.

    Article  PubMed  CAS  Google Scholar 

  52. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: American Psychiatric Press; 2000.

    Google Scholar 

  53. Spitzer RL, Kroenke K, Williams JBW, and the Patient Health Questionnaire Primary Care Study Group. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. JAMA. 1999;282:1737–44.

    Article  PubMed  CAS  Google Scholar 

  54. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606–13.

    Article  PubMed  CAS  Google Scholar 

  55. Spitzer RL, Kroenke K, Williams JB, Lowe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166:1092–7.

    Article  PubMed  Google Scholar 

  56. Kroenke K, Spitzer RL, Williams JB, Löwe B. An ultra-brief screening scale for anxiety and depression: the PHQ-4. Psychosomatics. 2009;50:613–21.

    PubMed  Google Scholar 

  57. Beck AT, Steer RA, Garbing MG. Psychometric properties of the Beck Depression Inventory: twenty-five years of evaluation. Clin Psychol Rev. 1988;8:77–100.

    Article  Google Scholar 

  58. Beck AT, Steer RA. Manual for the beck depression inventory. San Antonio: Psychological Corporation; 1993.

    Google Scholar 

  59. Beck AT, Epstein N, Brown G, Steer R. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol. 1988;56:893–7.

    Article  PubMed  CAS  Google Scholar 

  60. Weathers FW, Litz BT, Herman DS, et al. The PTSD Checklist (PCL): reliability, validity, and diagnostic utility. Proceedings of the Annual Conference of the International Society for Traumatic Stress Studies. San Antonio, Texas; October 25, 1993.

  61. Blanchard EB, Jones-Alexander J, Buckley TC, Forneris CA. Psychometric properties of the PTSD Checklist (PCL). Behav Res Ther. 1996;34:669–73.

    Article  PubMed  CAS  Google Scholar 

  62. Prins A, Ouimette P, Kimerling R, et al. The primary care PTSD screen (PC–PTSD): development and operating characteristics. Primary Care Psychiatry. 2004;9:9–14.

    Article  Google Scholar 

  63. Weathers FW, Huska JA, Keane TM. PCL-C for DSM-IV. Boston: National Center for PTSD Behavioral Science Division; 1991.

    Google Scholar 

  64. Saper JR, Lake AE. Borderline personality disorder and the chronic headache patient: review and management recommendations. Headache. 2002;42:663–74.

    Article  PubMed  Google Scholar 

  65. Hathaway SR, McKinley JC. The Minnesota multiphasic personality inventory manual. New York: Psychological Corporation; 1983.

    Google Scholar 

  66. Werder DS, Sargent JD, Coyne L. MMPI profiles of headache patients using self regulation to control headache activity. Headache. 1981;21:164–9.

    Article  PubMed  CAS  Google Scholar 

  67. Nicholson RA, Houle TT, Rhudy JL, Norton PJ. Psychological risk factors in headache. Headache. 2007;47:413–26.

    PubMed  Google Scholar 

  68. Heath RL, Saliba M, Mahmassani O, et al. Locus of control moderates the relationship between headache pain and depression. J Headache Pain. 2008;9:301–8.

    Article  PubMed  Google Scholar 

  69. Martin NJ, Holroyd KA, Penzien DB. The headache-specific locus of control scale: adaptation to recurrent headaches. Headache. 1990;30:729–34.

    Article  PubMed  CAS  Google Scholar 

  70. VandeCreek L, O’ Donnell F. Psychometric characteristics of the Headache-Specific Locus of Control Scale. Headache. 1992;32:239–41.

    Article  PubMed  CAS  Google Scholar 

  71. Bandura A. Social foundations of thought and action. A social cognitive theory. Englewood Cliffs: Prentice Hall; 1986.

    Google Scholar 

  72. French DJ, Holroyd KA, Pinell C, et al. Perceived self efficacy and headache-related disability. Headache. 2000;40:647–56.

    Article  PubMed  CAS  Google Scholar 

  73. Marlowe N. Stressful events, appraisal, coping, and recurrent headache. J Clin Psychol. 1986;54:247–56.

    Article  Google Scholar 

  74. Nicholson RA, Hursey KG, Nash J. Moderators and mediators of behavioral treatment for headache. Headache. 2005;45:513–9.

    Article  PubMed  Google Scholar 

  75. Smith T, Nicholson R. Are changes in cognitive and emotional factors important in improving in headache impact and quality of life? Headache. 2006;46:878.

    Google Scholar 

  76. Bond D, Dirge K, Rubingh C, et al. Impact of a self-help intervention on performance of headache management behaviors: a self-efficacy approach. Internet J Allied Health Sci Pract. 2004;2:1–12.

    Google Scholar 

  77. Nicholson RA, Nash J, Andrasik F. A self-administered behavioral intervention using tailored messages for migraine. Headache. 2005;45:1124–39.

    Article  PubMed  Google Scholar 

  78. Ellis A. Reason and emotion in psychotherapy. New York: Lyle Stewart; 1962.

    Google Scholar 

  79. Holroyd KA, Drew JB, Cottrell CK, et al. Impaired functioning and quality of life in severe migraine: the role of catastrophizing and associated symptoms. Cephalalgia. 2007;27:1156–65.

    Article  PubMed  CAS  Google Scholar 

  80. Sullivan MJL, Bishop SR, Pivik J. The Pain Catastrophizing Scale: development and validation. Psychol Assess. 1995;7:524–32.

    Article  Google Scholar 

  81. • Buse DC, Andrasik F, Sollars CM. Headaches. In: Andrasik F, Goodie J, Peterson A, editors. Biopsychosocial assessment in clinical health psychology: a handbook. New York: Guilford Press; 2012. This chapter reviews the utility and psychometric properties of a range of instruments useful for headache clinical practice and research in multiple domains..

    Google Scholar 

  82. Silberstein SD. Practice parameter: evidence-based guidelines for migraine headache (an evidence-based review): report of the quality standards subcommittee of the American academy of neurology. Neurology. 2000;55:754–62.

    PubMed  CAS  Google Scholar 

  83. Matchar DB, Harpole L, Samsa GP, et al. The headache management trial: a randomized study of coordinated care. Headache. 2008;48:1294–310.

    Article  PubMed  Google Scholar 

  84. Andrasik F, Grazzi L, Usai S, et al. Non-pharmacological approaches to treating chronic migraine with medication overuse. Neurol Sci. 2009;30 Suppl 1:S89–93.

    Article  PubMed  Google Scholar 

  85. Grazzi L, Andrasik F, Usai S, Bussone G. Treatment of chronic migraine with medication overuse: is drug withdrawal crucial? Neurol Sci. 2009;30 Suppl 1:S85–8.

    Article  PubMed  Google Scholar 

  86. Silberstein SD. Chronic daily headache. J Am Osteopath Assoc. 2005;105 Suppl 2:S23–9.

    Google Scholar 

  87. Dowson AJ, Tepper SJ, Baos V, et al. Identifying patients who require a change in their current acute migraine treatment: the Migraine Assessment of Current Therapy (Migraine-ACT) questionnaire. Curr Med Res Opin. 2004;20:1125–35.

    Article  PubMed  CAS  Google Scholar 

  88. • Lipton RB, Kolodner K, Bigal ME, et al. Validity and reliability of the migraine-treatment optimization questionnaire. Cephalalgia. 2009;29:751–9. This article describes the development and psychometric evaluation of the MTOQ-5. It also reviews treatment optimization and related clinical concepts..

    Article  PubMed  CAS  Google Scholar 

  89. Revicki DA, Kimel M, Beusterien K, et al. Validation of the revised patient perception of migraine questionnaire: measuring satisfaction with acute migraine treatment. Headache. 2006;46:240–52.

    Article  PubMed  Google Scholar 

  90. Chatterton ML, Lofland JH, Shechter A, et al. Reliability and validity of the migraine therapy assessment questionnaire. Headache. 2002;42:1006–15.

    Article  PubMed  Google Scholar 

  91. Lipton RB, Serrano D, Buse DC, et al. The Migraine Prevention Questionnaire (MPQ): development and validation. Headache. 2007;47:770–1.

    Article  Google Scholar 

  92. Buse DC, Pearlman SH, Reed ML, et al. Opioid use and dependence among persons with migraine: results of the AMPP study. Headache. 2012;52:18–36.

    Article  PubMed  Google Scholar 

  93. Radat F, Irachabal S, Lafittau M, et al. Construction of a medication dependence questionnaire in headache patients (MDQ-H) validation of the French version. Headache. 2006;46:233–9.

    Article  PubMed  Google Scholar 

  94. Akbik H, Butler SF, Budman SH, et al. Validation and clinical application of the Screener and Opioid Assessment for Patients with Pain (SOAPP). J Pain Symptom Manage. 2006;32:287–93.

    Article  PubMed  Google Scholar 

  95. Butler SF, Budman SH, Fernandez KC, et al. Development and validation of the current opioid misuse measure. Pain. 2007;130:144–56.

    Article  PubMed  Google Scholar 

  96. Buse DC, Steiner TJ, Serrano D, et al. Psychometric validity of the lifting the burden Headache Under-Response to Treatment (HURT) Index: a new instrument developed to improve management of headache. Headache. 2010;50:S42–3.

    Article  Google Scholar 

  97. Buse DC, Steiner TJ, Serrano D, et al. The Headache Under-Response to Treatment (HURT) index: an outcome measure to improve management of headache, especially in primary care. Neurology. 2010;74 Suppl 2:A323.

    Google Scholar 

  98. Al Jumah M, Al Khathaami A, Kojan S, et al. HURT Index in primary care: reliability and impact on headache management and patients’ satisfaction. J Neurol. 2010;257:S98.

    Article  Google Scholar 

Download references

Acknowledgements

The authors acknowledge the individuals who contributed to the development and testing of the HURT Questionnaire, including Dr. Manuela Fontebasso; Dott. Francesco S. Mennini; Susan W. Broner, MD; Ms. L. Ulla C. Schultz; and the members of the Lifting The Burden Outcome Measures Working Group. Additionally, we want to thank Daniel Serrano, PhD and Michael L. Reed, PhD for their work on the development and psychometric testing of the HURT Questionnaire, and Frank Andrasik, PhD for contributing psychometric information contained in this review.

Disclosures

Dr. Dawn C. Buse has received honoraria from Allergan Pharmaceuticals, Merck, Inc., MAP Pharmaceuticals, NuPathe, and Novartis. Dr. Timothy J. Steiner has received grants, honoraria, and/or research support from Actavis, AstraZeneca, Bayer Healthcare, and Merck and Co., and is a member of an advisory board to Bayer Healthcare. C. M. Sollars: none. Dr. Rigmor Højland Jensen is a member of the scientific advisory boards of Allergan Pharmaceuticals, ATI, Medotech, Neurocore, and Merck, Inc., and has received honoraria from Pfizer, Allergan, ATI, Medotech, Neurocore, and Merck, Sharpe, & Dohme. Dr. Mohammed A. Al Jumah has received research grants support or honoraria from Merck, Serono, Pfizer, Bayer, and Novartis. Dr. Richard B. Lipton has received grants and/or honoraria from Advanced Bionics, Allergan Pharmaceuticals, Endo Pharmaceuticals, GlaxoSmithKline, Minster, Merck, Inc., Neuralieve, Novartis, OrthoMcNeil, Pfizer, and ProEthics/KOWA.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dawn C. Buse.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Buse, D.C., Sollars, C.M., Steiner, T.J. et al. Why HURT? A Review of Clinical Instruments for Headache Management. Curr Pain Headache Rep 16, 237–254 (2012). https://doi.org/10.1007/s11916-012-0263-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11916-012-0263-1

Keywords

Navigation