Abstract
Myofascial pain syndrome is a disease of muscle that produces local and referred pain. It is characterized by a motor abnormality (a taut or hard band within the muscle) and by sensory abnormalities (tenderness and referred pain). It is classified as a musculoskeletal pain syndrome that can be acute or chronic, regional or generalized. It can be a primary disorder causing local or regional pain syndromes, or a secondary disorder that occurs as a consequence of some other condition. When it becomes chronic, it tends to generalize, but it does not change to fibromyalgia. It is a treatable condition that can respond well to manual and injection techniques, but requires attention to postural, ergonomic, and structural factors, and toxic or metabolic factors that impair muscle function.
Similar content being viewed by others
References and Recommended Reading
Simons DG, Travell JG, Simons LS: Myofascial Pain and Dysfunction: The Trigger Point Manual, vol 1, edn 2. Baltimore: Lippincott Williams & Wilkins; 1999. This is the major text in the field of myofascial pain. It details the principles of diagnosis and treatment, as well as outlines what is currently known about the nature of TrPs.
Carlsson CA, Nachemson A: Neurophysiology of Back Pain: Current Knowledge in Neck and Back Pain: The Scientific Evidence of Causes, Diagnosis, and Treatment. Edited by Nachemson A, Jonsson E. Philadelphia: Lippincott Williams & Wilkins; 2000:149–163.
Merskey H, Bogduk N: Classification of Chronic Pain, edn 2. Seattle: IASP Press; 1994.
Simons DG: Do endplate noise and spikes arise from normal motor endplates? Am J Phys Med Rehabil 2001, 80:134–140.
Hubbard DR, Berkoff GM: Myofascial trigger points show spontaneous needle EMG activity. Spine 1993, 18:1803–1807.
Hong C-Z, Torigoe Y, Yu J: The localized twitch responses in responsive taut bands of rabbit skeletal muscle are related to the reflexes at spinal cord level. J Musculoskeletal Pain 1995, 3:15–33.
Mense S, Simons DG: Muscle Pain. Baltimore: Lippincott Williams & Wilkins; 2001. Currently the most up-to-date exposition of pain of muscle origin, written by the researcher who has done much of the work on the central and peripheral responses to muscle pain, and by the person who developed or guided the major advances in myofascial pain studies.
Wolfe F, Smythe HA, Yunus MB, et al.: The American College of Rheumatology criteria for the classification of Fibromyalgia. Arthritis Rheum 1990, 33:160–172. Presents the basis for the diagnosis of fibromyalgia, and is widely used. Intended to standardize research criteria for the diagnosis, it has been widely adopted for clinical use.
Rau C-L, Russell IJ: Regional versus generalized muscle pain syndromes. Curr Rev Pain 1999, 3:85–95.
Russell IJ: Fibromyalgia syndrome. In Muscle Pain. Edited by Mense S, Simons DG. Baltimore: Lippincott Williams & Wilkins; 2001:289–337.
Saggini R, Giamberardino MA, Gatteschi L, Vecchiet L: Myofascial pain syndrome of the peroneus longus: biomechanical approach. Clin J Pain 1996, 12:30–37.
Delacerada FG: A comparative study of three methods of treatment for shoulder girdle myofascial syndrome. J Orthop Sports Phys Ther 1982, 4:51–54.
Zohn DA: The quadratus lumborum: an unrecognized source of back pain, clinical and thermographic aspects. Orthop Rev 1985, 14:163–168.
Fricton J: Myofascial pain. In Fibromyalgia and Myofascial Pain Syndromes. Edited by Masi AT. London: Bailliere Tindall; 1994:857–880.
Gerwin RD: Myofascial pain and fibromyalgia: diagnosis and treatment. J Back Musculoskeletal Rehabil 1998, 11:175–181.
Gerwin RD: Differential diagnosis of myofascial pain syndrome and fibromyalgia. J Musculoskeletal Pain 1999, 7:209–215.
Henriksson KG, Mense S: Pain and nociception in fibromyalgia: clinical and neurobiological considerations on aetiology and pathogenesis. Pain Rev 1994, 1:245–260.
Mense S: Descending antinociception and fibromyalgia. Z Rheumatol 1998, 57(suppl 2):23–26.
McDermid AJ, Rollman GB, McCain GA: Generalized hypervigilance in fibromyalgia: evidence of perceptual amplification. Pain 1996, 66:133–144.
Russell IJ, Orr MD, Littman B, et al.: Elevated cerebrospinal fluid levels of substance P in patients with the fibromyalgia syndrome. Arthritis Rheum 1994, 37:1593–1601.
Travell JG, Simons DG: Myofascial Pain and Dysfunction: The Trigger Point Manual, vol 2, edn 2. Baltimore: Williams & Wilkins; 1992.
Barnsley L, Lord S, Bogduk N: Whiplash injury. Pain 1993, 58:283–307.
Lord SM, Barnsley L, Wallis BJ, Bogduk N: Chronic cervical zygapophysial joint pain after whiplash. A placebocontrolled prevalence study. Spine 1996, 21:1737–1744.
Vecchiet L, Giamberardino MA, eds: Referred muscle pain and hyperalgesia from viscera. In Muscle Pain, Myofascial Pain, and Fibromyalgia: Recent Advances. New York, NY: Haworth Medical Press; 1999:61–69.
Wolfe F, Ross K, Anderson J, et al.: The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum 1995, 38:19–28.
Sola AE, Rodenberger ML, Getys BB: Incidence of hypersensitive areas in posterior shoulder muscles. Am J Phys Med Rehabil 1955, 34:585–590.
Macfarlane GJ: Fibromyalgia and chronic widespread pain. In Epidemiology of Pain. Edited by Crombie IK et al. Seattle: IASP Press; 1999:113–123.
Fillingim RB, ed: Sex, Gender, and Pain. Progress in Pain Research and Management, vol 17. Seattle: IASP Press; 2000.
LeResche L: Epidemiological perspectives on sex differences in pain. In Sex, Gender, and Pain. Edited by Fillingim RB. Seattle: IASP Press; 2000:233–249.
Jensen R, Rasmussen BK, Pedersen B, Olesen J: Muscle tenderness and pressure pain thresholds in headache. A population study. Pain 1993, 52:193–199.
Goulet J-P, Lavigne GJ, Lund JP: Jaw pain prevalence among French-speaking Canadians in Quebec and related symptoms of temporomandibular disorders. J Dent Res 1995, 74:1738–1744.
Drangsholt M, LeResche L: Temporomandibular disorder pain. In Epidemiology of Pain. Edited by Crombie IK et al. Seattle: IASP Press; 1999:203–233.
Rollman GB, Lautenbacher S: Sex differences in musculoskeletal pain. Clin J Pain 2001, 17:20–24.
Ryan EL: Pectoral girdle myalgia in women: a 5-year study in a clinical setting. Clin J Pain 2000, 16:298–303.
Skootsky SA, Jaeger B, Oye RK: Prevalence of myofascial pain in general internal medicine practice. West J Med 1989, 151:157–160.
Fishbain DA, Goldberg M, Meagher BR, et al.: Male and female chronic pain patients categorized by DSM-III psychiatric diagnostic criteria. Pain 1986, 26:181–197.
Magni G: The epidemiology of musculoskeletal pain. In Progress in Fibromyalgia and Myofascial Pain. Edited by Voeroy H, Merskey H. Amsterdam: Elsevier; 1993:3–21.
Linton S: The socioeconomic impact of chronic back pain: is anyone benefiting? Pain 1998, 75:163–168. This editorial is a very complete accounting of the economic problems produced by chronic back pain. It serves well as a model for understanding the impact chronic pain has on society as well as on the individual.
Taylor H, Curran NM: The Nuprin Pain Report. New York: Louis Harris and Associates; 1985.
Skovron ML, Szpalski M, Nordin M, et al.: Sociocultural factors and back pain: a population-based study in Belgian adults. Spine 1994, 19:129–137.
Hillman M, Wright A, Rajaratnam G, et al.: Prevalence of low back pain in the community: implications for service provision in Bradford, UK. J Epidemiol Community Health 1996, 50:347–352.
Gerwin RD: Management of persons with chronic pain. In Management of Persons with Chronic Neurologic Illness. Edited by Ozer MN. Boston, MA: Butterworth-Heinemann; 2000:265–290.
Lin TY, Teixeria MJ, Fischer AA, et al.: Work-related musculoskeletal disorders. In Myofascial Pain: Update in Diagnosis and Treatment. Edited by Fischer AA. Philadelphia: W.B. Saunders Company; 1997:113–118.
Simons DG, Hong C-Z, Simons L: Prevalence of spontaneous electrical activity at trigger spots and control sites in rabbit muscle. J Musculoskel Pain 1995, 3:35–48.
Gerwin R: A study of 96 subjects examined both for fibromyalgia and myofascial pain [abstract]. J Musculoskel Pain 1995, 3(suppl 1):121.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gerwin, R.D. Classification, epidemiology, and natural history of myofascial pain syndrome. Current Science Inc 5, 412–420 (2001). https://doi.org/10.1007/s11916-001-0052-8
Issue Date:
DOI: https://doi.org/10.1007/s11916-001-0052-8