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Endoscopic Resection of Sinonasal Malignancies

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Abstract

Malignant tumors of the sinonasal tract are rare, accounting for only 1% of all malignancies. Although they are associated with substantial histological heterogeneity, surgery plays a key role in their management. This review addresses the evolution of current treatments in view of the introduction of endoscopic resection techniques. The absence of facial incisions and osteotomies, decreased hospitalization time, better control of bleeding, improved visualization of tumor borders, and reduced morbidity and mortality rate are the major advantages of endoscopic techniques in comparison to traditional external approaches. The major criticisms focus on oncologic results in view of the short/intermediate follow-up of large series, which have commonly grouped together several histologies that may be associated with different prognoses. Since prospective studies contrasting the results of endoscopic and craniofacial resections are difficult to carry out given the rarity of the disease together with ethical issues, the creation of a large database would favor the analysis of several variables related to the patient, tumor, and treatment on survival performed on a large number of patients.

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References

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  1. Le QT, Fu KK, Kaplan M, et al: Treatment of Maxillary sinus carcinoma: a comparison of the 1997 and 1977 American Joint Committee on cancer staging systems. Cancer 1999, 86:1700–1711.

    Article  PubMed  CAS  Google Scholar 

  2. Tiwari R, Hardillo JA, Mehta D, et al: Squamous cell carcinoma of maxillary sinus. Head & Neck 2000, 22:164–169.

    Article  CAS  Google Scholar 

  3. Ketcham AS, Wilkins RH, Vanburen JM, Smith RR: A combined intracranial facial approach to the paranasal sinuses. Am J Surg 1963, 106:698–703.

    Article  PubMed  CAS  Google Scholar 

  4. Yuen AP, Fung CF, Hung KN: Endoscopic cranionasal resection of anterior skull base tumor. Am J Otolaryngol 1997, 18:431–433.

    Article  PubMed  CAS  Google Scholar 

  5. Thaler ER, Kotapka M, Lanza DC, et al: Endoscopically assisted anterior cranial skull base resection of sinonasal tumors. Am J Rhinol 1999, 13:303–310.

    Article  PubMed  CAS  Google Scholar 

  6. Stammberger H, Anderhuber W, Walch C, et al: Possibilities and limitations of endoscopic management of nasal and paranasal sinus malignancies. Acta Otorhinolaryngol Belg 1999, 53:199–205.

    PubMed  CAS  Google Scholar 

  7. Goffart Y, Jorissen M, Daele J, et al: Minimally invasive endoscopic management of malignant sinonasal tumours. Acta Otorhinolaryngol Belg 2000, 54:221–232.

    PubMed  CAS  Google Scholar 

  8. Casiano RR, Numa WA, Falquez AM. Endoscopic resection of esthesioneuroblastoma. Am J Rhinol 2001, 15:271–279.

    PubMed  CAS  Google Scholar 

  9. Kühn UM, Mann WJ, Amedeo RG. Endonasal approach for nasal and paranasal sinus tumor removal. ORL Otorhinolaryngol Relat Spec 2001, 63:366–371.

    Google Scholar 

  10. Devaiah AK, Larsen C, Tawfik O, et al: Esthesioneuroblastoma: endoscopic nasal and anterior craniotomy resection. Laryngoscope 2003, 113:2086–2090.

    Article  PubMed  Google Scholar 

  11. Roh HJ, Batra PS, Citardi MJ, et al: Endoscopic resection of sinonasal malignancies: a preliminary report. Am J Rhinol 2004, 18:239–246.

    PubMed  Google Scholar 

  12. Bockmuhl U, Minovi A, Kratzsch B, et al: Endonasal micro-endoscopic tumor surgery: state of the art. Laryngorhinootologie 2005, 84:884–891.

    Article  PubMed  CAS  Google Scholar 

  13. Poetker DM, Toohill RJ, Loehrl Ta, et al: Endoscopic management of sinonasal tumors: a preliminary report. Am J Rhinol 2005, 19:307–315.

    PubMed  Google Scholar 

  14. Yuen AP, Fan YW, Fung CF, et al: Endoscopic-assisted cranionasal resection of olfactory neuroblastoma. Head Neck 2005, 27:488–493.

    Article  PubMed  Google Scholar 

  15. Chen MK. Minimally invasive endoscopic resection of sinonasal malignancies and skull base surgery. Acta Otolaryngol 2006, 126:981–986.

    Article  PubMed  Google Scholar 

  16. Dave SP, Bared A, Casiano RR. Surgical outcomes and safety of transnasal endoscopic resection for anterior skull tumors. Otolaryngol Head Neck Surg 2007, 136:920–927.

    Article  PubMed  Google Scholar 

  17. Lund V, Howard DJ, Wei WI. Endoscopic resection of malignant tumors of the nose and sinuses. Am J Rhinol 2007, 21:89–94.

    Article  PubMed  Google Scholar 

  18. Podboj J, Smid L. Endoscopic surgery with curative intent for malignant tumors of the nose and paranasal sinuses. Eur J Surg Oncol 2007, 33:1081–1086.

    PubMed  CAS  Google Scholar 

  19. •• Ong YK, Solares CA, Carrau RL, Snyderman CH. New developments in transnasal endoscopic surgery for malignancies of the sinonasal tract and adjacent skull base. Curr Opin Otolaryngol Head Neck Surg 2010, 18:107–113. This is a recent review of the latest technological advances and refinements in surgical techniques that allowed an expansion of the indications of transnasal endoscopic surgery.

    Article  PubMed  Google Scholar 

  20. Nicolai P, Castelnuovo P, Lombardi D, et al: Role of endoscopic surgery in the management of selected malignant epithelial neoplasms of the naso-ethmoidal complex. Head Neck 2007, 29:1075–1082.

    Article  PubMed  Google Scholar 

  21. Carrau RL, Kassam AB, Snyderman CH, et al: Endoscopic transnasal anterior skull base resection for the treatment of sinonasal malignancies. Op Tech Otolaryngol 2006, 17:102–110.

    Article  Google Scholar 

  22. • Nicolai P, Battaglia P, Bignami M, et al: Endoscopic surgery for malignant tumors of the sinonasl tract and adjacent skull base: A 10-year experience. Am J Rhinol 2008, 22:308–316. This article summarizes the experience of two tertiary care centers with 184 patients undergoing endoscopic surgery (alone or in combination with frontal craniotomy) for sinonasal malignancies. The results suggest that endoscopic surgery, when properly planned and in expert hands, is a valid alternative to standard surgical procedures.

    Article  PubMed  Google Scholar 

  23. Bhatki AM, Carrau RL, Snyderman CH, Prevedello DM, Gardner PA, Kassam AB. Endonasal surgery of the ventral skull base—endoscopic transcranial surgery. Oral Maxillofac Surg Clin North Am 2010, 22:157–168.

    Article  PubMed  Google Scholar 

  24. Hadad G, Bassagasteguy L, Carrau RL, et al: A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap. Laryngoscope 2006, 116:1882–1886.

    Article  PubMed  Google Scholar 

  25. Kassam AB, Thomas A, Carrau RL, et al: Endoscopic reconstruction of the cranial base using a pedicled nasoseptal flap. Neurosurgery 2008, 63 (1 Suppl. 1):ONS44-53.

    Google Scholar 

  26. Zanation AM, Snyderman CH, Carrau RL, et al: Minimally invasive endoscopic pericranial flap: a new method for endonasal skull base reconstruction. Laryngoscope 2009, 119:13–18.

    Article  PubMed  Google Scholar 

  27. Fortes FS, Carrau RL, Snyderman CH, et al: Transpterygoid transposition of a temporoparietal fascia flap: a new method for skull base reconstruction after endoscopic expanded endonasal approaches. Laryngoscope 2007, 117:970–976.

    Article  PubMed  Google Scholar 

  28. Fortes F, Carrau R, Snyderman C, et al: The posterior pedicle inferior turbinate flap: a new vascularized flap for skull base reconstruction. Laryngoscope 2007, 117:1329–1332.

    Article  PubMed  Google Scholar 

  29. Prevedello DM, Barges-Coll J, Fernandez-Miranda JC, et al: Middle turbinate flap for skull base reconstruction: cadaveric feasibility study. Laryngosocpe 2009, 119:2094–2098.

    Article  Google Scholar 

  30. Oliver CL, Hackman TG, Carrau RL, et al: Palatal flap modifications allow pedicled reconstruction of the skull base. Laryngoscope 2008, 118:2102–2106.

    Article  PubMed  Google Scholar 

  31. Rivera-Serrano CM, Oliver CL, Sok J, Prevedello DM, Gardner P, Snyderman CH, Kassam AB, Carrau RL. Pedicled facial buccinator (FAB) flap: a new flap for reconstruction of skull base defects. Laryngoscope 2010, 120:1922–1930.

    Article  PubMed  Google Scholar 

  32. • Villaret AB, Yakirevitch A, Bizzoni A, et al: Endoscopic transnasal craniectomy in the management of selected sinonasal malignacies. Am J Rhinol Allergy 2010, 24:60–65. This article specifically addresses the problems of anterior skull base defect reconstruction after endoscopic surgery for malignancies of the sinonasal tract. The procedure was found to be associated with acceptable morbidity.

    Article  PubMed  Google Scholar 

  33. Lund VJ, Stammberger H, Nicolai P, et al: European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol Suppl 2010, 1:1–143.

    Google Scholar 

  34. Bogaerts S, Vander Poorten V, Nuyts S, et al: Results of endoscopic resection followed by radiotherapy for primarily diagnosed adenocarcinomas of the paranasal sinuses. Head & Neck 2008, 30:728–736.

    Article  Google Scholar 

  35. Jardeleza C, Seiberling K, Floreani S, Wormald PJ. Surgical outcomes of endoscopic management of adenocarcinoma of the sinonasal cavity. Rhinology 2009, 47:354–361.

    PubMed  Google Scholar 

  36. Unger F, Haselberger K, Walch C, et al: Combined endoscopic surgery and radiosurgery as treatment modality for olfactory neuroblastoma (esthesioneuroblastoma) Acta Neurochirurgica 2005, 147:595–602.

    Google Scholar 

  37. Germani RM, Vivero R, Herzallah IR, Casiano RR. Endoscopic reconstruction of large anterior skull base defects using acellular dermal allograft. Am J Rhinol 2007, 21:615–618.

    Article  PubMed  Google Scholar 

  38. Folbe A, Herzallah I, Duvurri U, et al: Endoscopic endonasal resection of esthesioneuroblastoma: a multicenter study. Am J Rhinol Allergy 2009, 23:91–94.

    Article  PubMed  Google Scholar 

  39. • Hanna E, DeMonte F, Ibrahim S, et al: Endoscopic resection of sinonasal cancers with and without craniotomy. Arch Otolaryngol Head Neck Surg 2009, 135:1219–1224. Based on a retrospective review of 120 patients treated at the M.D. Anderson Cancer Center for sinonasal cancer with endoscopic surgery (alone or combined with frontal craniotomy), the authors conclude that in well-selected patients and with appropriate use of adjuvant therapy, endoscopic resection results in acceptable oncologic outcomes.

    Article  PubMed  Google Scholar 

  40. Eloy JA, Vivero RJ, Hoang K, et al: Comparison of transnasal endoscopic and open craniofacial resection for malignant tumors of the anterior skull base. Laryngoscope 2009, 119:834–840.

    Article  PubMed  Google Scholar 

  41. Devaiah AK, Andreoli MT. Treatment of esthesioneuroblastoma: a 16-year meta-analysis of 361 patients. Laryngoscope 2009, 119:1412–1416.

    Article  PubMed  Google Scholar 

  42. Pant H, Bhatki AM, Snyderman CH, et al: Quality of life following endonasal skull base surgery. Skull Base 2010, 20:35–40.

    Article  PubMed  Google Scholar 

  43. de Almeida JR, Snyderman CH, Gardner PA, et al: Nasal morbidity following endoscopic skull base surgery: A prospective cohort study. Head Neck 2010, [Epub ahead of print].

  44. Gil Z, Abergel A, Spektor S, et al: Patient, caregiver, and surgeon perceptions of quality of life following anterior skull base surgery. Arch Otolaryngol Head Neck Surg 2004, 130:1276–1281.

    Article  PubMed  Google Scholar 

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Correspondence to Piero Nicolai.

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Nicolai, P., Castelnuovo, P. & Bolzoni Villaret, A. Endoscopic Resection of Sinonasal Malignancies. Curr Oncol Rep 13, 138–144 (2011). https://doi.org/10.1007/s11912-011-0151-6

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